Having reached 30, Koscielny is due one last long term contract of his professional career before age starts to take
over his effect on the game and so if he is to secure a big money move away to one of Europe's top clubs, then it may have to be sooner rather than later.
Even the National Toxicology Program says there is «some concern»
over its effects on infants and children.
There is worse news: Venezuela's crumbling political order could have a spill
over effect on regional stability and Colombia's fragile peace — as well as encourage the global expansion of transnational organized criminal and terrorist networks.
For example, the welfare loss due to sea level rise in the central Europe North region or to the agricultural losses in southern Europe would have a spill
over effect on the whole Europe due to economic interlinkages.
Controversy reigns
over the effects on the heart of passive smoking.
Agricultural use of lindane was banned in 2006 due to concerns
over its effects on the nervous system.
Both exercises have cross
over effects on the upper and lower chest.
This energy can have a spill -
over effect on older men as well, making them feel younger.
And something whose demand is shooting through the roof will perhaps have a spill -
over effect on its clones, which is why... [Read more...]
There are wide ranging worries
over their effects on health.
The positive effects on administrative efficiency, transparency and quality of services are likely to have positive spill -
over effects on the private sector's competitiveness, and thus also have a positive impact on employment.
According to an article published on Bloomberg, the increased frenzy over bitcoin in Japan is causing some spill -
over effects on some of the country's small - cap stock market companies.
Not exact matches
Important factors that could cause actual results to differ materially from those reflected in such forward - looking statements and that should be considered in evaluating our outlook include, but are not limited to, the following: 1) our ability to continue to grow our business and execute our growth strategy, including the timing, execution, and profitability of new and maturing programs; 2) our ability to perform our obligations under our new and maturing commercial, business aircraft, and military development programs, and the related recurring production; 3) our ability to accurately estimate and manage performance, cost, and revenue under our contracts, including our ability to achieve certain cost reductions with respect to the B787 program; 4) margin pressures and the potential for additional forward losses
on new and maturing programs; 5) our ability to accommodate, and the cost of accommodating, announced increases in the build rates of certain aircraft; 6) the
effect on aircraft demand and build rates of changing customer preferences for business aircraft, including the
effect of global economic conditions
on the business aircraft market and expanding conflicts or political unrest in the Middle East or Asia; 7) customer cancellations or deferrals as a result of global economic uncertainty or otherwise; 8) the
effect of economic conditions in the industries and markets in which we operate in the U.S. and globally and any changes therein, including fluctuations in foreign currency exchange rates; 9) the success and timely execution of key milestones such as the receipt of necessary regulatory approvals, including our ability to obtain in a timely fashion any required regulatory or other third party approvals for the consummation of our announced acquisition of Asco, and customer adherence to their announced schedules; 10) our ability to successfully negotiate, or re-negotiate, future pricing under our supply agreements with Boeing and our other customers; 11) our ability to enter into profitable supply arrangements with additional customers; 12) the ability of all parties to satisfy their performance requirements under existing supply contracts with our two major customers, Boeing and Airbus, and other customers, and the risk of nonpayment by such customers; 13) any adverse impact
on Boeing's and Airbus» production of aircraft resulting from cancellations, deferrals, or reduced orders by their customers or from labor disputes, domestic or international hostilities, or acts of terrorism; 14) any adverse impact
on the demand for air travel or our operations from the outbreak of diseases or epidemic or pandemic outbreaks; 15) our ability to avoid or recover from cyber-based or other security attacks, information technology failures, or other disruptions; 16) returns
on pension plan assets and the impact of future discount rate changes
on pension obligations; 17) our ability to borrow additional funds or refinance debt, including our ability to obtain the debt to finance the purchase price for our announced acquisition of Asco
on favorable terms or at all; 18) competition from commercial aerospace original equipment manufacturers and other aerostructures suppliers; 19) the
effect of governmental laws, such as U.S. export control laws and U.S. and foreign anti-bribery laws such as the Foreign Corrupt Practices Act and the United Kingdom Bribery Act, and environmental laws and agency regulations, both in the U.S. and abroad; 20) the
effect of changes in tax law, such as the
effect of The Tax Cuts and Jobs Act (the «TCJA») that was enacted
on December 22, 2017, and changes to the interpretations of or guidance related thereto, and the Company's ability to accurately calculate and estimate the
effect of such changes; 21) any reduction in our credit ratings; 22) our dependence
on our suppliers, as well as the cost and availability of raw materials and purchased components; 23) our ability to recruit and retain a critical mass of highly - skilled employees and our relationships with the unions representing many of our employees; 24) spending by the U.S. and other governments
on defense; 25) the possibility that our cash flows and our credit facility may not be adequate for our additional capital needs or for payment of interest
on, and principal of, our indebtedness; 26) our exposure under our revolving credit facility to higher interest payments should interest rates increase substantially; 27) the effectiveness of any interest rate hedging programs; 28) the effectiveness of our internal control
over financial reporting; 29) the outcome or impact of ongoing or future litigation, claims, and regulatory actions; 30) exposure to potential product liability and warranty claims; 31) our ability to effectively assess, manage and integrate acquisitions that we pursue, including our ability to successfully integrate the Asco business and generate synergies and other cost savings; 32) our ability to consummate our announced acquisition of Asco in a timely matter while avoiding any unexpected costs, charges, expenses, adverse changes to business relationships and other business disruptions for ourselves and Asco as a result of the acquisition; 33) our ability to continue selling certain receivables through our supplier financing program; 34) the risks of doing business internationally, including fluctuations in foreign current exchange rates, impositions of tariffs or embargoes, compliance with foreign laws, and domestic and foreign government policies; and 35) our ability to complete the proposed accelerated stock repurchase plan, among other things.
To create the right sound, he's layering that metal -
on - metal
effect over the sound of a didgeridoo and adding echo.
If you're still seething about the
effects Wall Street's collapse has had
on your business, the books in this list right here could give you some closure, or put you
over the edge.
China's crackdown has so far appeared to have little
effect on bitcoin's price, with investors from neighbouring South Korea and Japan taking
over in the trade where Chinese investors left off.
The American Meteorological Society published research in 2011 that found current temperature has a bigger
effect on our happiness than variables like wind speed and humidity, or even the average temperature
over the course of a day.
Even the «Deflategate» controversy
over the New England Patriots» inadequately inflated footballs and their
effect on play was settled by data science.
«Having spare time and perceiving control
over how to spend that time (i.e. discretionary time) has been shown to have a strong and consistent
effect on life satisfaction and happiness, even controlling for the actual amount of free time one has.»
One possible side
effect of the Academy's tendency to prefer smaller, more exquisite films
over splashy popcorn titles has been
on ratings for the Oscars broadcast.
Over time, as people became more and more aware of the
effects commonly used products can have
on the environment, plastic - happy clients who once cared mostly for cost and convenience morphed into savvy customers with real concerns about the impact polyethylene and other petroleum - based products have
on the ecosystem.
While the loss of the city has no immediate
effect on oil exports, now at
over three million barrels a day, it adds to concerns
over security and the country's plans to expand oil production.
The app produces a set of graphs so you can compare the
effect a factor had
on your symptoms
over time or compare the severity of two symptoms.
The latest report from the International Panel
on Climate Change, an intergovernmental group charged with researching the
effects of carbon emissions, said at the end of September that climate change is unequivocal and that going forward, sea levels will rise at a faster rate than they have
over the past 40 years.
As Sy explains, the President - elect's picks for various cabinet posts — apart from his selection of Rep. Tom Price to head the Department of Health and Human Services — could well have a significant
effect on Americans» health and well - being
over the next several years.
A recent study published in the American Sociological Review clearly showed that, in a white collar environment, allowing workers some control
over their own schedules, including being able to work from home, had a positive
effect on employees» work - family balance without sacrificing productivity.
But, this constant work mindset can have a negative
effect on your personal well - being
over time.
Tom Wynn, director of affluent research at Spectrem, provided several factors for the increased confidence: the steady improvement in job growth, the steady increase in the major stock market indices since the spring, and a decrease in political ambiguity with the election season
over, which has an
effect on at least some people's outlook.
In fact, men with all skin types will appreciate the products moisturizing properties that leave skin feeling supple and healthy and the lubricating
effects that help a razor slide smoothly
over the face and neck without getting caught
on hairs.
The Joint Committee
on Taxation, the official government scorekeeper, projected in its analysis released Thursday that the bill would add 0.8 % to GDP
on average
over the first 10 years after the bill went into
effect.
And while early results have been promising, some skeptics have held out
on the hype due to concerns
over side
effects and whether results will persist in later - stage trials.
And
over time this has an insidious
effect on the free media because people start to check themselves, understanding that critiquing the president can actually hurt their bosses, or their media conglomerates bottom line.
«Their courage can have a buoying
effect on everyone else — but they too will become risk averse
over time as they encounter failure,» she explains.
The series of studies tested the
effects of power hierarchies
on team productivity by creating teams with either a mixed propensity towards leadership — in one case some participants were primed to feel powerful by thinking of a time they wielded power
over others while others subjects were asked to envision a time they were bossed around before joining the group — or teams made up entirely of hard charging leadership types or participants primed for a meeker, go along, get along approach.
Economic research is making increasingly clear that increased trade with China
over the last 25 years had significant, negative
effects on workers in certain parts of the country, like the industrial town in Ohio where Vance grew up, though perhaps not as negative as widely believed in those regions.
Sprout's controversial pink libido pill was approved
on Tuesday by the U.S. Food and Drug Administration for pre-menopausal women, after being rejected twice
over concerns about its effectiveness and side -
effects.
After a successful preliminary health care vote
on Tuesday, Senate GOP leaders may have a new plan to get their health legislation
over the finish line: pass what, in
effect, could amount to a blank legislative check.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required
on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the
effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products
over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact
on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
However,
on Wednesday the Senate Public Utilities Committee canceled plans to send Senate Bill 58 to the floor for a full chamber vote at least until next year
over concerns about the
effects of the bill's proposed changes.
This assertion had three components: (1) The commenter estimated the cost
over 60 days to be $ 250 million based
on the
on - going cost from the final 2016 RIA of $ 1.5 billion per year, (2) that cost savings
over a 10 - year period were not provided to allow comparison to the negative
effects on investors that would occur
over the ten year period, (3) that industry cost savings were not projected out
over 10 years using returns
on capital in a similar manner to investors» lost earnings.
Including just the
effects of economic feedback from deficit reduction would reduce the cumulative deficit
over the next 10 years by roughly $ 160 billion — or about 0.1 percent of GDP,
on average — compared with CBO and JCT's conventional estimate of the President's proposals.
While the hype around artificial intelligence is in the short term is overblown,
over the long run it will have a massive
effect on the asset management business.
At the meeting, a lunch event put
on by the Economic Club of Canada, Pilla emphasized
over and
over again the
effect the plan would have
on patients.
CAP assumes annual wage growth matches the mean
effect of experience and nonexperience
on real wages measured in the NLSY data assuming full - time, full - year employment, and reports the cumulative difference between the no - leave earnings profile and the leave earnings profile
over time.
Shares fell last week after Axios reported last Wednesday that Trump was considering changes to the retailer's tax treatment, in part because of anger
over how Amazon has hurt the commercial real estate industry because of its negative
effect on brick - and - mortar retailers.
«The previously reported challenges in Western Canada that have had a negative
effect on our results
over the past three quarters deepened through the fourth quarter...,» said Poulin said in the earnings release.
The
effect of stagnating incomes continues to spill
over into the larger economy, weighing
on the housing recovery and consumer spending.
But none of globalization's
effects on inflation, not even the potential reduction in inflationary bias, diminish the importance of the principal objective of central banks: setting policy to achieve low and stable rates of inflation
over time.
However, if one focuses
on the resulting growth of credit
over the recent period or the movements in long - term interest rates, the
effects are less concerning.
Much of the debate
over Trump's trade policy seems to miss the point that the economic
effects of any trade measure depend
on how it affects capital.