Sentences with phrase «overactive genes»

The team uncovered different kinds of dependencies that cancer cells exploit, such as underactive or overactive genes.

Baliga and his team edited the genome of M. tuberculosis, disabling the regulatory machinery responsible for some of the overactive genes.

Not exact matches

The critter's secret weapon is an overactive version of the gene for a protein — Wnt10b — that regulates the formation of flab.

The drug turns off some of the regulators for the overactive tuberculosis gene network that was fighting off the bedaquiline.

Researchers found two genes that were overactive in tuberculosis bacteria tolerant to the drug bedaquiline.

The HER2 gene is overactive in more than one - fifth of all breast cancers and operates in a host of other tumors that may prove vulnerable to oleic acid.

In 2006, researchers discovered the genetic defect behind FOP: A mutated version of the gene ACVR1, which in patients produces an overactive form of a cell surface protein called a transmembrane receptor.

The group took the first step toward their goal of a novel engineering strategy for yeast by creating what is known as a cDNA library: a collection of over 90 % of the genes from the genome of baker's yeast (Saccharomyces cerevisiae), arranged within a custom segment of DNA so that each gene will be, in one version, overactive within a yeast cell, and in a second version, reduced in activity.

The researchers found that in B cell tumors, mutated overactive versions of the Notch protein directly drive the expression of the Myc gene and many other genes that participate in B cell signaling pathways.

Combining iPSC lines, and bone cancer driven by p53 mutations in LFS patients, the research team revealed for the first time that the LFS bone cancer results from an overactive p53 gene.

The researchers suggested that men and women who are thought to be at higher risk of developing schizophrenia might be diagnosed through the use of a genetic test for this overactive form of the dopamine receptor gene.

Drug developers, meanwhile, are exploring compounds that may be capable of thwarting epigenetic modifications that cause key genes to become under - or overactive, thereby promoting cancer and other diseases.

An overactive immune system due to dysfunctional PINK1 and Parkin genes could explain why dopaminergic neurons die in Parkinson's patients.

When the gene is overactive (as it seems to be in some people with OCD), too much serotonin is taken out between cells, leaving too little for the brain to use.