Sentences with phrase «overall outcome of treatment»

Not exact matches

The primary outcome with the largest difference in this sensitivity analysis was preterm birth, where an analysis restricted to trials with lower risk of bias suggested a larger treatment effect: RR 0.64, (95 % CI 0.51 to 0.81) compared with RR 0.77, (95 % CI 0.62 to 0.94) in the overall analysis.

As we are now able to focus our efforts on improving the overall patient experience and reducing the risk of relapse, the leading cause of death after transplant, we have greatly improved long - term survival outcomes for patients who before might not have had another treatment option.»

ADAPT - DES is the largest study ever to explore the overall treatment implications of platelet reactivity on patient outcomes after successful coronary drug - eluting stent implantation.

However, it is well known that these treatments are not effective for all patients and that overall outcomes have not improved palpably in recent decades, potentially due to the lack of new interventions or better matching of patients to available treatments.

The practice - based network will be a key resource to examine outcomes of spatial neglect assessment, and prism adaptation treatment, to assess whether these care processes enhance functional recovery and overall quality of life.

Acute myeloid leukemia (AML) is the leading cause of leukemia mortality in the United States.1 Curative treatment involves intensive induction chemotherapy, before proceeding to either consolidation chemotherapy or allogeneic stem cell transplantation based on the patient's risk for relapse.2 This approach has been employed for > 4 decades and, although most individuals achieve complete remissions with front - line therapy, 3 the majority of patients ultimately relapse with drug - resistant disease, and overall survival rates remain disappointingly poor.4 The limited ability of many patients to tolerate the intense chemotherapy - based treatments, in particular hematological toxicity, further contributes to the poor outcomes noted in this disease.

Both DOCC and EUC showed improved outcomes, 13 but DOCC showed significantly greater reductions in the severity of behavior problems, hyperactivity, and internalizing problems, greater remission of behavior and internalizing problems, and a higher proportion of overall treatment responders.

The program of prenatal and infancy home visiting by nurses, tested with a primarily white sample, produced a 48 percent treatment - control difference in the overall rates of substantiated rates of child abuse and neglect (irrespective of risk) and an 80 percent difference for families in which the mothers were low - income and unmarried at registration.21 Corresponding rates of child maltreatment were too low to serve as a viable outcome in a subsequent trial of the program in a large sample of urban African - Americans, 20 but program effects on children's health - care encounters for serious injuries and ingestions at child age 2 and reductions in childhood mortality from preventable causes at child age 9 were consistent with the prevention of abuse and neglect.20, 22

There are well - documented associations between posttraumatic stress disorder (PTSD) and intimate relationship problems, including relationship distress and aggression, 1 and studies demonstrate that the presence of PTSD symptoms in one partner is associated with caregiver burden and psychological distress in the other partner.2 Although currently available individual psychotherapies for PTSD produce overall improvements in psychosocial functioning, these improvements are not specifically found in intimate relationship functioning.3 Moreover, it has been shown that even when patients receive state - of - the - art individual psychotherapy for the disorder, negative interpersonal relations predict worse treatment outcomes.4, 5

The pattern of results for predictors and moderators needs to be examined in the context of the overall study findings, which showed no overall difference between the minimal intervention bibliotherapy group and the therapist - led treatments, no differences in outcomes overall between the two types of therapists, nurses, and psychologists, and dose effects when parents attended a sufficient number of sessions, a number that exceeds the number of sessions that families often attend in clinic settings.

Summary: (To include comparison groups, outcomes, measures, notable limitations) Participants were randomized, by pairs, into the Individual Family Psychoeducation (IFP, otherwise known as Individual Family - Psychoeducational Psychotherapy (PEP)-RRB- plus treatment as usual (IFP + TAU, n = 10) condition, or into a waitlist - control condition plus TAU (WLC + TAU, n = 10) Measures included the Children's Interview for Psychiatric Syndromes — Child and Parent Forms; the Children's Depression Rating Scale — Revised (CDRS - R) and Mania Rating Scale (MRS) in order to assess severity of mood impairment; and Mood Severity Index (MSI), which measured overall mood severity.

The main difference between mediated moderation and moderated mediation is that for the former there is initial (overall) moderation and this effect is mediated and for the latter there is no moderation but the effect of either the treatment on the mediator (path A) is moderated or the effect of the mediator on the outcome (path B) is moderated.

This Brief summarizes findings from the impact evaluation of the Ghana Livelihood Empowerment Against Poverty (LEAP) programme on schooling outcomes overall and for various subgroups: by sex, age group and cognitive ability.The findings underscore the importance of going beyond average treatment effects to analyse impacts by subgroup in order to unpack the programme effect