Sentences with phrase «overall survival»

Despite advances in surgery and chemotherapy over the past 20 years, only modest progress has been made in improving overall survival in patients with ovarian cancer.

Overall survival rate in dogs with heat stroke is approximately 50 %.

There have been several recent advances and overall survival of our patients with these cancers is improving.

In one study, patients treated with surgery, radiation therapy and chemotherapy had median overall survival times of 32 months.

However, the therapy did not improve overall survival and it did not work if the cancer had spread to other parts of the body, the agency noted.

The researchers found that the two - year overall survival for patients who were treated with either surgery or RT increased from 61 % in 2000 to 70 % in 2009.

The 3 - year overall survival for the study population was 94 % and the event - free survival was 91 %.

However, the trials did not show any improvement in overall survival with intermittent therapy (26, 27).

He concluded that the improvement in progression - free survival and potential for overall survival benefit should lead to a phase III trial of this therapy option in small - cell lung cancer.

The researchers examined 63 indications for approval and found that only 30 percent of them were approved based on overall survival.

There was no difference in overall survival between the two groups.

The investigators also measured overall survival from the beginning of induction therapy, and found the same result.

In the most recent results of the trial, treatment increased median overall survival by two months in patients treated according to protocol.

The study follows emerging research in pediatric oncology finding that low - income status predicts poor adherence to oral chemotherapy and decreased overall survival.

Next steps for this research include a larger, randomized phase III trial to test progression - free survival, as well as overall survival.

They note that it's the strongest independent variable predicting overall survival.

Finally, all of this data can be combined to predict patient outcomes including overall survival.

Without tracking an organism over its life span and in a complicated and changing environment, it's hard to say whether observed changes will translate into overall survival.

These data may guide surgical counseling beyond expected overall survival to include quality of life.

The app, which alerts patients to complete a symptom chart on a weekly basis, boosts overall survival by seven months compared to when patients receive standard follow - up care alone.

While younger patients have a better prognosis, overall survival rates are very poor and new treatments are needed.

There was no statistically significant difference in median overall survival.

Whereas these risks become notable early on, improved overall survival is only recognized in the long term.

Overall survival for babies born at 22 weeks remained the same throughout the study, at just 4 percent.

Researchers found significant differences in overall survival between those on the drug and those on the placebo in the older age group.

In pSTAT3 - negative tumors, napabucasin monotherapy resulted in significantly worse overall survival compared with placebo.

This was comparable to those without HIV, whose overall survival at one year was 87.7 percent.

Among those patients who underwent early transplant, those with elevated CRP had significantly worse overall survival compared with normal CRP levels (91 months vs not reached; P =.011).

In a second, late - breaking presentation, Dr Andrea Necchi, attending physician in the Department of Medical Oncology at the Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy, said results from the phase III KEYNOTE - 045 trial showed that treatment with pembrolizumab resulted in longer overall survival with fewer side - effects for patients with previously treated advanced bladder (urothelial) cancer compared with patients given chemotherapy.

Napabucasin did not increase overall survival compared with placebo in the overall population of patients with advanced colorectal cancer in the study, but did significantly improve survival among patients with phosphorylated STAT3 (pSTAT3)- positive tumors.

Furthermore, antiviral treatment significantly prolonged overall survival compared to the control group (HR = 0.059, 95 % CI = 0.008 - 0.415; p = 0.005).

Study in partnership with the Alliance for Clinical Trials in Oncology is the first large controlled trial to show overall survival benefit in FLT3 - mutated AMLAML is the most common acute leukemia in...

Patients who were taking antacids had significantly better overall survival than those who did not take them.

Depression has been associated with increased likelihood of not getting the best treatment, as well as lower overall survival in other cancers, including breast and liver cancers.

Extending platinum - free interval with pegylated liposomal doxorubicin, topotecan, or gemcitabine does not improve overall survival among patients with recurrent ovarian cancer.

In this video Dr. Odunsi discusses a new study that found that higher T - cell diversity in ovarian cancer is associated with poor overall survival.

Overall survival did not correlate with the combined outcomes of CR and VGPR.

The 3 - month overall survival rate was 65 % for nivolumab monotherapy and 64 % for the combination.

One promising solution to increase long - term overall survival has been in the area of allogeneic hematopoietic stem cell transplantation (HCST).

They also analyzed PSA expression in 556 human tumors and found low PSA expression associated with shorter overall survival.

At five - years post-treatment, patients in the HFX arm had the highest overall survival rates at 37.1 percent (HR 0.81, 95 percent CI), compared to 33.7 percent for the AFX - C arm, 29.3 percent for the SFX arm, 29.0 percent for the AFX - S arm.

Subgroup analyses showed trends or significant overall survival improvements for all subgroups measured, including by disease stage, ECOG score, age, and other factors.

Immunotherapy doubles overall survival and improves quality of life, with fewer side effects, in a treatment - resistant and rapidly progressing form of head and neck carcinoma, reports a large, randomized international trial co-led by investigators at the University of Pittsburgh Cancer Institute (UPCI).

Why the drug combination did not prolong the time before the disease progress — as might be expected, because it did extend overall survival — is not clear, the researchers said.