An unfortunate characteristic of the inherited form of copper toxicosis is that irreversible adverse changes occur in the liver tissue a considerable time before
any overt signs of the disease occur in the dog.
Not exact matches
Unfortunately, this does not necessarily result in the development
of overt, clinically observable symptoms - Thornburg and his colleagues (1985) reported that
overt clinical
signs of liver
disease do not generally occur until the dog is several years old.
Dogs may show clinical
signs at any stage
of development
of the
disease, although many dogs with hip dysplasia do not show
overt clinical
signs.
Some early
signs of heart
disease may be detectable during a clinical examination by your vet, prior to the onset
of any
overt signs.
For this reason, routine annual visits (or every 6 months for geriatric pets 8 years or older) to your vet are recommended as they may identify subtle changes long before
overt signs of heart
disease develop.