Sentences with phrase «own cohorts of patients»

The company is partnering up with a group of clinicians at Stanford, as well as telemedicine vendor American Well, to test whether Apple Watch's heart rate sensor can detect abnormal heart rhythms in a cohort of patients, according to two people familiar.

Use our advance computer vision, deep learning and artificial intelligence technologies to analyze your own cohorts of patients to gain genomic insights and discoveries

Khachaturian says a proper test of Roses» findings — using Roses» methods in a larger cohort of patients — has not yet been done.

The UC research team looked at 3,679 individuals with Type 2 diabetes from a de-identified cohort of patients at the Cincinnati Veterans Affairs Medical Center and who were followed for a 10 - year period, explains Charuhas Thakar, MD, professor and director of the UC Division of Nephrology, Kidney CARE Program.

«Our new study indicates that a differential therapeutic approach can be beneficial for older patients in melanoma and suggests that age should be taken into account to design better treatments for certain cohorts of patients.»

A phase II basket study is ongoing to determine whether these early results can be confirmed in a much larger cohort of patients.

Adams points out that Cohort A is the first phase II study of an immunotherapy for triple negative breast cancer to be reported and represents the largest cohort of patients with mTNBC treated with immunotherapy to date.

The trial investigated the drug in two separate cohorts of patients: Cohort A, which included 170 patients with heavily pretreated metastatic triple negative breast cancer (mTNBC) regardless of PD - L1 expression, and Cohort B, which included 52 patients with PD - L1 - positive tumors who received it as first - line therapy.

And for researchers studying the organ, new questions are emerging about how the environment, lifestyle or genetics of this small cohort of patients might predispose them to appendicitis even as it becomes less common.

In the cohort of patients who received transplants from mismatched unrelated donors, all 43 patients received four doses of abatacept with a calcineurin inhibitor and methotrexate.

We got permission to continue following the patients in this study and we also recruited a second cohort of patients to try to run a series of placebo controlled studies.

«The findings need to be confirmed using targeted RNA sequencing, or internal validation, and then tested in a new cohort of patients, or external validation.

The team then validated these findings in a cohort of patients with type 2 diabetes.

This led to the collection of bone marrow samples from larger cohorts of patients with the Ottawa Hospital Research Institute, as well as those from Western University and Hamilton Health Sciences, for the next steps of investigation.

The earlier discovery of mutations in UBQLN2 gene, which causes ALS and ALS / dementia in children and adults, in the Siddique lab led to the screening of the UBQLN family of genes in a large cohort of patients with familial ALS, resulting in the identification of the UBQLN4 mutation.

The results were confirmed in a genome - wide association study and replicated in 1,745 patients in four independent cohorts of patients with IBS and control subjects.

Dr. Anne, together with first author Harriet Eldredge - Hindy, M.D., showed that this same cohort of patients will likely have a reduced risk of ischemic heart disease after 10 years.

«The study represents the largest cohort of patients with OACICH to date and reports 2 clinically valuable associations.

Conducting a cross-sectional study of a large cohort of patients with different levels of cognitive impairment and different disease stages, the researchers found that the amounts of a TREM2 fragment in the cerebrospinal fluid were highest during early stages characterized by mild cognitive impairment symptoms.

A cohort of patients treated with the immune checkpoint inhibitor ipilimumab (207 patients) showed similar results.

They analyzed the association between body mass index (weight divided by height) and progression - free survival (PFS) and overall survival (OS) in six independent cohorts of patients treated with targeted therapy, immunotherapy or chemotherapy in pivotal trials that led to FDA approval of these drugs.

They evaluated four independent cohorts of patients with metastatic GEA.

For the study, the researchers studied 769 patients enrolled in the TBI Model Systems database, an ongoing multi-center cohort of patients funded by the National Institute on Disability and Rehabilitation Research.

Additional potential novel biomarkers will also be evaluated and reported in this cohort of patients.

Conclusions and Relevance The study results, derived from a large cohort of patients with long follow - up time, suggest that the rate of revision septorhinoplasty is low, but certain patient characteristics are associated with higher revision rates.

You found it by looking for rare germline variants in a cohort of patients with a specific form of cancer.

The study results, derived from a large cohort of patients with long follow - up time, suggest that the rate of revision septorhinoplasty is low, but certain patient characteristics are associated with higher revision rates.

«In this study we were able to demonstrate the clinical utility of Prosigna in a real world setting by testing a comprehensive population - based cohort of patients,» stated Dr. Bent Ejlertsen of the Danish Breast Cancer Cooperative Group.

This study demonstrates the importance of a well - characterized cohort of patients and controls along with detailed clinical information about their experience of illness.

Rather we are exploring a third solution where we modify the cells to create universal cell lines that can be transplanted into large cohorts of patients.

Among a smaller cohort of patients for whom serum sRAGE levels were available, there were lower levels seen in those taking short - acting CCBs compared with any other type of antihypertensive medication (P =.032).

Ms. Leach won Best Poster entitled, «Prevalence of mono - allelic MUTYH carrier status in patients of varied ancestries» and was also selected for a podium presentation of another abstract, «Identification of APC I1307K Among a Cohort of Patients Undergoing a Pan-Cancer Gene Panel: Analysis of Ancestry - Based Cancer History».

«Completing enrollment and dosing of the first cohort of patients receiving 20 million AST - OPC1 cells marks another important milestone for our SCiStar study.

Using ddPCR, the team detected and quantified five strains of HPV cfDNA in blood samples from a small cohort of patients with recurrent metastatic HPV - positive OPSCC, who were undergoing either conventional treatment or immunotherapy.

She has been involved in the identification of early biomarkers of placental damage in cohorts of patients at high risk of pregnancy complications, with specific focus on the role of autoimmunity and of vascular inflammation.

Outlier - based identification of copy number variations using targeted resequencing in a small cohort of patients with tetralogy of fallot

Tanguy Seiwert, M.D., of The University of Chicago, presented results of a phase 1b trial of Merck's pembrolizumab in a cohort of patients with advanced head and neck cancer.

Our findings are potentially applicable to early disease detection, and future test development should focus on longitudinal sampling of the microbiota to monitor for changes in microbial diversity in a larger cohort of patients.

Here, we report the largest cohort of patients with HUWE1 variants, consisting of 14 females and 7 males, with 15 different missense variants and one splice site variant.

Conti V, Leone MC, Casato M, Nicoli M, Granata G, Carlesimo M. High prevalence of gluten sensitivity in a cohort of patients with undifferentiated connective tissue disease.

Prevalence of parietal cell antibodies in a large cohort of patients with autoimmune thyroiditis.

Thus antibiotic prophylaxis for this cohort of patients is not supported by current evidence.

This study reports on a different cohort of patients from Bologna who received an idiosyncratic and rather eclectic form of CBT which included advice on lifestyle changes and a form of «well being therapy.»

This Finnish nationwide cohort study examines the comparative effectiveness of pharmacologic treatments in the prevention of rehospitalization in a nationwide cohort of patients with bipolar disorder.

Not exact matches

Indeed a paper published earlier this year in the Journal of Perinatology analyzed homebirths attended by a certified nurse midwife (CNM) and found that they had double the risk of neonatal death of CNM attended hospital births, even though the hospital birth cohort included high risk patients.

In the first study evaluating patient - reported cosmetic outcomes in a population - based cohort of older women with breast cancer, The University of Texas MD Anderson Cancer Center researchers found that less radiation was associated with improved cosmetic satisfaction long - term.

CDI's platform is especially helpful in constructing panels for biomarker discovery, because researchers can begin by using patient samples or banked samples to compare immune profiles of cohorts that show particular symptoms (or no symptoms in the case of control samples).

Seventeen patients had undergone treatment before Gelsinger, who was in the final cohort — the one receiving the highest dose of the therapy.

While further study of larger patient groups with longer follow - up times is needed for this cohort of prostate cancer patients, this study is pivotal in providing evidence for change in practice.»

Co-author Subrata Sen, Ph.D., also a professor of Molecular Translational Pathology, notes, «These findings are a significant advance considering that there's nothing else available now to detect early stage pancreatic cancer that has gone through blinded validations in multiple patient cohorts.»