Sentences with phrase «own immune system cells»

When you or your child comes in contact with egg proteins, immune system cells (antibodies) recognize them and signal the immune system to release histamine and other chemicals that cause allergic signs and symptoms.

Taking a closer look, the team found that the onset of sepsis disrupts the normal activity of specific interferons, signaling proteins used for communication between immune system cells.

The experiments point to an immune system cell that evades the toxic effects of cyclophosphamide and protects patients from a lethal form of GVHD.

In reaction to infection or inflammation, immune system cells known as effector T cells (Teffs) undergo rapid changes - arming themselves and diversifying into groups that target specific diseased cells.

A second type of immune system cell, called regulatory T cells (Tregs), are a model of constancy, remaining stable even as Teffs go into battle mode.

In a study published in the journal Science, an international collaboration of investigators from Dana - Farber, Harvard Medical School, Boston Children's Hospital, and the University of Strasbourg uncovered a mechanism that allows key immune system cells to keep a steady rein on their more belligerent brother cells, thereby protecting normal, healthy tissue from assault.

The protein has long been considered too complex to target with a drug as it also is crucial to proper function of many immune system cells, not just B cells gone bad.

Researchers injected both the naked virus and SEVI - treated HIV into the tails of rats that had been given human immune system cells.

The researchers found that HIV spiked into semen was more successful than the virus alone at infecting T cells and macrophages (immune system cells that are believed to be the infection's initial targets in the body).

Researchers are developing many different versions of CAR - T cell therapies, but the basic premise is the same: Doctors remove a patient's T cells (immune system cells that attack invaders) from a blood sample and genetically modify them to produce artificial proteins on their surfaces.

«Common cancers evade detection by silencing parts of immune system cells.»

In a related paper published online today in Nature Biotechnology, Konrad Hochedlinger of the Harvard Stem Cell Institute in Cambridge and his colleagues compared the gene expression patterns in mouse iPS cells derived from white blood cells, muscle precursor cells, immune system cells called B cells, and fibroblasts taken from tail tips.

The researchers used «humanized mice,» which have had their immune systems replaced with human immune system cells, thymus tissue and bone marrow.

«Hodgkin lymphoma is unusual among cancers in that it consists of a small number of tumor cells in a sea of inflammatory cells and immune system cells, including T cells that don't work very effectively.»

By combining multiple images, the researchers produced movies correlating the production of hydrogen peroxide to the activities of the immune system cells.

The study included 124 newly diagnosed patients at 25 clinical trial sites in the U.S. Two - thirds of the patients were treated with ICT - 107, an experimental vaccine based on immune system cells called dendritic cells that were exposed to six synthetic proteins, or antigens, known to be involved in GBM development.

«Immune system found to control eye tissue renewal in zebrafish: Discovery suggests that strategies to regulate immune system cell reactivity to injury and cell loss might one day unlock and boost human tissue and cellular regeneration.»

In 2010, it was discovered that enhancers directed expression of RNA on a broad scale in neurons and macrophages, a type of immune system cell.

Key immune system cells produced before birth may survive well into adulthood, according to new research published in PLOS Computational Biology.

GM - CSF helps improve the function of existing immune system cells and prompts the bone marrow to make new cells, which can help normalize the immune response.

Chronic low level inflammation, prompted by cholesterol build - up in immune system cells, may have a key role, the findings suggest.

Because the antigens were the only possible source of TB exposure, Dr. Srivastava says, antigen transfer from infected dendritic cells had to be the avenue for their absorption by other immune system cells in the lymph nodes.

HIV - 1 integrates its own genome into the genome of human immune system cells known as CD4 + T cells, hijacking their cellular machinery to make more copies of itself.

The trouble is that the virus targets not only the lymphocyte cells, which include T cells — a key component of the body's immune system helping to fight diseases — but also other immune system cells.

An international research team headed by the rheumatologist Dr Andreas Ramming at Friedrich - Alexander - Universität Erlangen - Nürnberg (FAU) has now managed to identify an immune system cell type that can be used in a targeted attempt to control the inflammatory response in arthritis patients.

Two types of vaccines were used for the study: one constructed with genetically engineered DNA molecules that teach immune system cells to recognize premalignant cells expressing HPV16 E7 proteins, and one that is a non-infectious, engineered virus that targets and kills precancerous cells marked by HPV16 and HPV18 E6 and E7 proteins.

For instance, a tumor influences the expression of genes in immune system cells that are involved in the body's response to cancer.

In both types of MS, immune system cells attack and strip away myelin, the fatty protective sheathing that insulates nerve cells.

It occurs when immune system cells from the donor proliferate and attack the host's tissues.

The cells produce chemicals, called cytokines, which then stimulate other immune system cells.

HIV - 1 infects and kills immune system cells, including T cells and macrophages that were used in the study.

The scientists at Leiden University Medical Center (LUMC) have shown that immune system cells, which react to gluten, produce chemicals called cytokines that can contribute to the development of a rare form of lymphoma (cancer of the white blood cells).

Researchers have found that pregnancy - related stress hormones shield the fetus by causing attacking immune system cells, or T cells, to self - destruct.

For example, he's designing nanoparticles that bait specific immune system cells by displaying certain features on their surface; inside, the nanoparticles contain an antigen of a particular microbe.

«The retraction states that Mignot and his colleagues were unable to replicate the results of the ELISpot assay, a widely used method for measuring how immune system cells such as T cells respond to fragments of foreign proteins, called antigens,» Underwood writes.

Celiac disease is an autoimmune disease where special immune system cells, called gluten - specific T cells, have an extraordinarily strong inflammatory reaction to gluten.

While immune system cells» purpose is to defend and protect the body, ironically the brain's «call to arms» may cause more harm than good when it instructs immune cells to enter into the brain.

The researchers used RNAi to block three genes: two found in the virus itself and one found in mouse T cells — the primary immune system cells infected by the virus.

Because of the work of several other collaborators, Haughey says, his team knew that some sort of inflammation - promoting molecule was released from brain and targeted to the liver after brain injury to send immune system cells to the damaged area, but the identity of this go - between had been elusive for years.

These memory cells then lead other immune system cells into battle against invaders.

A TROPICAL disease that can fatally damage the heart may take hold in the human body by causing important immune system cells to commit suicide, according to a Brazilian research team.

Think about all the different ways you can study a particular disease, such as Crohn's: Should we look at immune system cells in the gut?

Consistent with other studies, they found that as early as 13 weeks of development, the fetus was producing a range of immune system cells, including dendritic cells, which recognize invaders and signal other immune cells to attack.

All immune system cells are made from stem cells in the bone marrow.

Genome studies show that several such viruses, including one that infects mouse mammary cells and has been linked to cancer, have something in common — a sequence of DNA similar to that found in immune system cells.

A snippet of genetic code normally expressed in immune system cells can trigger the disease when its part of a virus's DNA.

The sequence, called an ITAM (immunoreceptor tyrosine - based activation motif), encodes a piece of protein that can by itself signal immune system cells to multiply and go to work.

And that, said Melton, suggests the need to enter as - yet little - explored terrain: developing ES cells into immune system cells.

Victora is researching the immune system cells that produce antibodies that protect us from infectious diseases.

At the same time, the drugs can spark a reduction in immune system cells known as T regulatory cells (Tregs), which usually tamp down the immune response to disease or infection.