Sentences with phrase «own oligomerization»

RIPK2 works in conjunction with NOD1 and NOD2 (nucleotide - binding oligomerization domain) proteins in controlling responses by the immune system that lead to this inflammation process.

They are assembled by oligomerization of triple - helical protomers and are covalently crosslinked, a key reinforcement that stabilizes networks.

Mutations that abolished CED - 4 oligomerization inactivated its ability to activate CED - 3.

Oligomerization is different from other self - catalyzed reactions of the intervening sequence RNA in that it involves intermolecular rather than intramolecular recombination, producing RNA molecules that are substantially larger than the original.

This oligomerization induced CED - 3 proximity and competed with CED - 4: CED - 9 interaction.

The observation that RNA molecules can catalyze their own oligomerization has possible implications for the evolution of chromosomes and for the replicative cycle of plant viroids and virus - associated RNA's.

Sometimes, proteins must be in an «oligomeric» state to be functional, although «oligomerization» of certain proteins can also lead to diseases.

The balance of expression of mutant and wild - type ACVR1 protein is likely to affect ligand binding dynamics, receptor oligomerization, internalization, and / or activation of downstream signaling pathways, as well as receptor response to environmental triggers that are clinical features of the natural history of FOP.

The nucleotide - binding oligomerization domain - containing protein 1 (NOD1) polymorphism S7N does not affect receptor function.

Kampf, C. J., F. Liu, K. Reinmuth - Selzle, T. Berkemeier, H. Meusel, M. Shiraiwa and U. Pöschl: Protein Cross-Linking and Oligomerization through Dityrosine Formation upon Exposure to Ozone, Environmental Science & Technology 49, 10859 — 10866, 2015.

We discovered that levuglandins can greatly accelerate the oligomerization of amyloid beta and that the oligomers so formed are neurotoxic.

Systematic comparison of the effects of alpha - synuclein mutations on its oligomerization and aggregation.

Nonvisual arrestin oligomerization and cellular localization are regulated by inositol hexakisphosphate binding.

Mislocalization of Oligomerization - Incompetent RDS is Associated with Mislocalization of Cone Opsins and Cone Transducin.

A major lab project involves the study of prohormone convertase enzymology and potential dominant negative effects (effects of oligomerization, the role of the inhibitory tail domain, and cellular targeting).

Disruption of oligomerization induces nucleocytoplasmic shuttling of leukemia - associated rho Guanine - nucleotide exchange factor.

Retinoic Acid - induced Gene - I (RIG - I) Associates with Nucleotide - binding Oligomerization Domain - 2 (NOD2) to Negatively Regulate Inflammatory Signaling.

Paladino, Simona, et al. «Protein oligomerization modulates raft partitioning and apical sorting of GPI - anchored proteins.»

JAIN, R., et al. «Oligomerization of green fluorescent protein in the secretory pathway of endocrine cells.»

This makes sense as oligomerization is required to marshal the cellular forces needed to deal with these ER problems.

So certain mutations and membrane situations can affect the oligomerization state.

These structures prevent end - to - end interactions that lower the solubility of RiAFP and lead to oligomerization and aggregation.

In this case, Tao found that the protein has a distinctive loop that is essential for self - oligomerization and encapsidation of the viral genome into a double - helical hairpin structure.

Not only does their work demonstrate that scientists have a basic understanding of what determines oligomerization, it also shows that they can design proteins with tunable shape, size, and symmetry for a variety of biological applications.

Structural determinants of human proton - coupled folate transporter oligomerization: role of GXXXG motifs and identification of oligomeric interfaces at transmembrane domains 3 and 6

In these fusions, ultraviolet light exposure caused oligomerization of the Dronpa domains thereby occluding the enzyme active site and shutting off the enzyme.

Later exposure to cyan light stopped Dronpa oligomerization and turned the enzymes back on.