Sentences with phrase «own opiate receptors»

Opiates, of course, are natural or synthetic substances that bind to opiate receptors in the brain, and are chemically similar to alkaloid compounds derived from Papaver somniferum, or the opium poppy.

Uhl and his colleagues, Ichiro Sora and Zaijie Wang, of Johns Hopkins University and the National Institute on Drug Abuse (NIDA) zeroed in on the gene encoding the mu opiate receptor — sections of which they first identified a decade ago.

Uhl and crew then produced mice that had half the normal number of opiate receptors and as a result, experienced greater discomfort when exposed to a standard mildly painful stimulus.

PET scans have demonstrated that some individuals have twice as many mu opiate receptors in certain brain regions as others.

Knockout mice, which completely lacked the gene and so manufactured no mu opiate receptors, were all the more sensitive.

«Among the many people who contributed to this area, my own special thanks go to Candace Pert who, as a graduate student, identified the opiate receptors in my laboratory.»

«I am honored that the Lasker Foundation has chosen this year to recognize the field of opiate receptor and opiate - like peptide research,» he said.

But it was Pert's supervisor, Solomon Snyder, who in 1978 shared the prestigious Albert Lasker Basic Medical Research Award with two scientists working in Scotland, Hans Kosterlitz and John Hughes, the first to isolate the enkephalins, natural chemicals that bind to the opiate receptors.

Given via injection or nasal spray, naloxone binds powerfully with opiate receptors in the brain, repelling the drugs the user has taken and sending him or her into an instant and painful withdrawal.

Looking at previous work on other addictions, such as alcoholism, we anticipated that pathological gamblers would have increased opiate receptors which we did not find, but we did find the expected blunted change in endogenous opioids from an amphetamine challenge.

Serendipitously, that was the moment, in 1973, that scientists discovered the opiate receptor — the first neurochemical receptor in the brain.

«Could the opiate receptor become a therapeutic target?

These findings, together with data reported several years ago on the treats» ability to turn on opiate receptors in the brain (SN: 10/12/96, p. 235), threaten to transform the image of chocolate from dietary vice to herbal medicine.

He pioneered the labeling of receptors by reversible ligand binding in the identification of opiate receptors and extended this technique to all the major neurotransmitter receptors in the brain.

Snyder is a recipient of the 1978 Albert Lasker Basic Medical Research Award for identifying the relation of opiate receptors to naturally - ocurring enkephalins.

Opiate receptor research has paid off both in fundamental understanding of brain function and in the development of novel therapeutic agents.

Independent of the brain effects already discussed, gliadin peptides may travel through the blood stream and can stimulate opiate receptors in the brain, resulting in their being termed gliadorphins, accounting for temporary withdrawal symptoms!

Dr. Candace Pert has confirmed as much through her discovery of the bodily opiate receptor and research on neuropeptides demonstrating that that emotions are literally encoded throughout organs and tissues.

Independent of the brain effects already discussed, gliadin peptides may travel through the blood stream can stimulate opiate receptors in the brain resulting in their being termed gliadorphins.

My naturopath told me last year that milk is addictive to our brains because milk has something in it that binds to the opiate receptors in our brains, as does gluten.

«milk is addictive to our brains because milk has something in it that binds to the opiate receptors in our brains, as does gluten.

Dr. Justin Marchegiani: But the CBD, it's still hitting the Opiate receptor though, a little bit, isn't it?

Uhm — But, it's also blocking the Opiate receptors in our Immune System, in our Pituitary gland, and all [stutters] the Gluteal cells in our brain.

... Opiate receptor site, and then, there's some compounds that are produced to help modulate the Immune System help that, the T - regulatory cells, to kind of balance out that...

Uhm — «Cause — «Cause eventually, the body starts to downregulate the Opiate receptors.

Opiate Receptors are almost everywhere in your body.

His theory goes that the wheat we eat today was hybridized 50 years ago, and now contains gliadin, one of two proteins that make up gluten and which binds to opiate receptors in our brains and stimulates our appetite.

These morphine like compounds fit into the opiate receptor in your brain causing a similar response like heroin or vicodine.

De Meirleir explained that LDN is an opiate receptor blocker and is used in very small doses (0.5 - 5.5 mg / day) relative to its normal dosing (5 grams, which is 5000 mg).

So, essentially what you're doing when you block opiate receptors is you cause the body to make more endorphins.

But it blocks opiate receptors.

Laughing releases endorphins, the brain's «feel good» hormones that activate the body's opiate receptors, reducing pain while increasing pleasure.

Not exact matches

«The reason why opiates are so deadly is because, what happens is those opiates sit on the receptors in your brain,» said Sen. David Carlucci.

There, he continued his opiate - receptor research, but a particular opiatelike receptor, named «sigma,» began to monopolize his attention.

Located in the central nervous system and peripheral tissues, sigma receptors bind opiates and various antipsychotic drugs.

At Cornell, Bowen wrote a research proposal to examine the mechanism of action between opiates and their receptors, a mechanism that was largely unknown at the time.

Following chronic opiate exposure, however, opiate reward memory formation becomes independent of D1R, and rather depends on a second dopamine receptor, called D2r, and a protein called CaMKII.

Ledent et al. «Unresponsiveness to Cannabinoids and Reduced Addicitive Effects of Opiates in CB1 Receptor Knockout Mice», Science, 283 (5400): 401 - 404, 1999.

These chemicals cross the blood - brain barrier, enter the brain and bind to the same receptors that bind opiates like morphine and heroin, triggering a mild euphoria.

This medication blocks a particular type of opioid receptor and has been used for many years as treatment for a narcotic overdose and to reduce the incidence of relapse in alcoholism and opiate addiction.

Yet another pain - relieving drug is THC, the active component in marijuana, which controls pain by stimulating certain receptors in the brain, similar to those that opiates act upon.

Opiates or opioids bind to receptors in the brain, the nervous system and the digestive tract.

Opiates / opioids bind to receptors all over the body, they are especially concentrated in areas of the brain that control breathing, pain and emotions.

It turns out that the partial blockage of the opioid receptors tricks the brain into producing more of its own opiates, thus reducing pain and improving sleep (but not generally reducing fatigue).

These additional dog pain relievers may include opioid type drugs, opiate - like drugs or drugs that work on the nerve - pain receptor (31).

The most popular «narcotic» drug for dogs, Tramadol, is a synthetic that has «opiate - like» mu - receptor properties and activity [8].

Buprenorphine, an opiate, is a mu receptor.