An unusual lawsuit filed last month sheds light on a scientific misconduct investigation into a prominent cardiac
stem cell lab.
In science news around the world, the U.S. Food and Drug Administration (FDA) cracks down on
stem cell labs, Brazil opens one of its largest national reserves to gold and iron mining, and the International Atomic Energy Agency launches a global bank for low - enriched uranium.
«Postdocs and students who are currently working in
stem cell labs are finding themselves very highly marketable, but they should also think about how the field will transform in five or 10 years, about the bigger picture, and how to ask questions and develop expertise that will be relevant over the long term,» says Watt.
4 Epidermal
Stem Cell Lab, Department of Bioscience Technology, Chung Yuan Christian University, Chung - Li, Taiwan
In 2015, he turned research into realty when he built a state - of - the - art
stem cell lab.
Because he has set up his own
stem cell lab and has purchased the required radiology equipment, he is able to inject stem cells into the blown discs.
Not exact matches
The only problem I have is creating fetuses in a
lab to extract more
stem cells.
In 2010, researchers from the University of Michigan Comprehensive Cancer Center published a study in the journal Clinical Cancer Research showing that sulforaphane had the ability to kill breast cancer
stem cells in mice and in
lab cultures, and it also prevented the growth of new tumor
cells.
Lab - grown tissues derived from patients»
stem cells may also allow researchers to screen drugs and test their effectiveness on diseases like cancer.
But the next big question was whether these
cells could home in on tumors in
lab dishes, and in animals, like neural
stem cells.
Culturing
stem cells by day, and audiences in dingy stand - up clubs by night, it wasn't until Helen Pilcher left the
lab that she started basing her comedy on science.
The Muotri
lab uses induced pluripotent
stem cells from patients with autism and schizophrenia to look for biomarkers of these conditions.
Research on
lab animals has shown that the number of hypothalamus
stem cells diminishes with age.
Lab - grown
stem cells can make the hormone EPO, which has notoriously been used in sports doping.
He ruled that work on existing embryonic
stem cell lines derived outside federally funded
labs did not violate a ban on the destruction of embryos.
TWO types of human ear
cell have been grown in the
lab from fetal
stem cells.
Beginning in the 1970s, physicians learned how to harvest skin
stem cells from a patient with extensive burn wounds, grow them in the laboratory, then apply the
lab - grown tissue to close and protect a patient's wounds.
In
lab dishes, the blast
cells formed tissues that resembled blood - forming
stem cells as well as blood vessels, the group found.
«I'm working with Professor Richard Oreffo and Dr Rahul Tare from the University's Centre for Human Development,
Stem Cells and Regeneration who are trying to create and grow cartilage in the lab using a patients» own (autologous) stem cells to then be implanted back into the patient if they have a cartilage defect,» she expla
Stem Cells and Regeneration who are trying to create and grow cartilage in the lab using a patients» own (autologous) stem cells to then be implanted back into the patient if they have a cartilage defect,» she expl
Cells and Regeneration who are trying to create and grow cartilage in the
lab using a patients» own (autologous)
stem cells to then be implanted back into the patient if they have a cartilage defect,» she expla
stem cells to then be implanted back into the patient if they have a cartilage defect,» she expl
cells to then be implanted back into the patient if they have a cartilage defect,» she explains.
Setton says the multistep process her
lab used to derive NP - type
cells from the hiPSCs provides the necessary quality control as scientists seek additional uses for
stem cell therapies.
For example, animal studies have shown that neurons derived in the
lab from human embryonic
stem cells improve Parkinson's symptoms; however, any residual
stem cells associated with those neurons could form masses of unwanted
cells.
Starting in 2007, in the same French Institute of Health and Medical Research (INSERM)
lab where he did his Ph.D., Catelain worked to harness the potential of embryonic
stem cells for treating cardiac diseases.
The two - part approach netted a set of mutations seen only at relapse that enabled the team to sift and sort leukemic and normal
stem cells using tools developed in the Dick
lab a few years ago to zero in on specific
cell types fated to relapse.
Shane Mayack was a postdoc in the
lab of Amy Wagers at Harvard University's Joslin Diabetes Center, studying blood
stem cells.
Buer Sen, MD, first author of the
Stem Cells paper and research associate in Rubin's
lab, used cytochalasin D to break up the actin cytoskeleton.
A former postdoctoral researcher who worked in the
lab of a promising
stem cell biologist engaged in scientific misconduct, faking images and other data in two papers that were later retracted, according to U.S. government investigators.
I couldn't resist composing this after the mention of the charmingly misspelled word «hematopoetic» in your story on blood grown in the
lab from
stem cells (12 November, p 8):
Thanks to crucial contributions from three young
lab members, he said, his team succeeded in converting mature skin
cells into pluripotent
stem cells.
«My sense is that there are different groups out there doing this kind of work, but they haven't opened up their
labs» to reporters, says
stem cell biologist Paul Knoepfler at the
Stem cell researchers at UConn Health have reversed Prader - Willi syndrome in brain
cells growing in the
lab, findings they recently published in the Human Molecular Genetics.
The problem follows close on the heels of Hwang's admission that, despite his previous denials, two members of his
lab had donated oocytes for his group's
stem cell experiments and other donors had been paid for their donations (Science, 2 December, p. 1402).
The new epidermis, grown from human pluripotent
stem cells, offers a cost - effective alternative
lab model for testing drugs and cosmetics, and could also help to develop new therapies for rare and common skin disorders.
Zheng, together with Leah Boyer, then a researcher in Gage's
lab and now director of Salk's
Stem Cell Core, generated diseased neurons by taking skin cells from patients with Leigh syndrome, reprogramming them into stem cells in culture and then coaxing them to develop into brain cells in a d
Stem Cell Core, generated diseased neurons by taking skin
cells from patients with Leigh syndrome, reprogramming them into
stem cells in culture and then coaxing them to develop into brain cells in a d
stem cells in culture and then coaxing them to develop into brain
cells in a dish.
«Our paper is a blueprint of how the cartilage - producing
cell, called a chondrocyte, is made and maintained by Sox9,» said He, a postdoctoral research associate in the lab of Andy McMahon, director of the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at
cell, called a chondrocyte, is made and maintained by Sox9,» said He, a postdoctoral research associate in the
lab of Andy McMahon, director of the Eli and Edythe Broad Center for Regenerative Medicine and
Stem Cell Research at
Cell Research at USC.
At a press conference, Harvard officials also announced the establishment of a new iPS «core»
lab at the Harvard
Stem Cell Institute to speed the development of the new cell types and their dissemination to researchers around the wo
Cell Institute to speed the development of the new
cell types and their dissemination to researchers around the wo
cell types and their dissemination to researchers around the world.
The plaintiffs... claim [ed] that the inquiry into their
lab at BWH wrongfully damaged their professional reputations, derailed the sale of their
stem cell company, and cost them lucrative job offers.»
In a boon to
stem cell research and regenerative medicine, scientists at Boston Children's Hospital, the Wyss Institute for Biologically Inspired Engineering at Harvard University and Boston University have created a computer algorithm called CellNet as a «roadmap» for
cell and tissue engineering, to ensure that
cells engineered in the
lab have the same favorable properties as
cells in our own bodies.
The UK also offers a favorable funding and regulatory climate, says Minger, whose
lab works on the therapeutic and clinical applications of
stem cell research.
In collaboration with Ding, the
lab of Olivier Voinnet at the Swiss Federal Institute of Technology in Zurich also reported in an accompanying paper the detection of viral siRNAs in cultured mouse embryonic
stem cells infected by the Encephalomyocarditis virus.
The disease model, described in a new study by a UC San Francisco - led team, involves taking skin
cells from patients with the bone disease, reprogramming them in a
lab dish to their embryonic state, and deriving
stem cells from them.
Transplants grown from
stem cells in the
lab can help replenish the blood and have been used to cure anaemia in mice.
Those hoping for quick clinical success should remember it takes time for revolutionary treatments to go from
lab bench to bedside, says Andras Nagy, a
stem cell researcher at Mount Sinai Hospital's Lunenfeld — Tanenbaum Research Institute in Toronto, who has not been directly involved in Yamanaka's work.
Using next - generation sequencing technologies that were previously unavailable, Michael Gardner, a graduate research assistant, and Jianying Wang, a senior research associate in Mitchum's
lab, made a remarkable new discovery — nematodes possess the ability to produce a second type of peptide that can effectively «take over» plant
stem cells that are used to create vital pathways for the delivery of nutrients throughout the plant.
Around 2000, then - postdoc Wagers and other researchers in Irving Weissman's and Thomas Rando's
labs at Stanford revived the method, known as parabiosis, to study the fate of blood
stem cells and muscle
cells.
Glioblastomas in
lab dishes and mouse brains are fakes, little Potemkin villages that everyone thought were faithful replicas of human glioblastomas but which, lacking tumor
stem cells, were nothing of the kind.
O'Shea, a professor in the Department of
Cell & Developmental Biology and director of the U-M Pluripotent
Stem Cell Research
Lab, and McInnis, the Upjohn Woodworth Professor of Bipolar Disorder and Depression in the Department of Psychiatry, are co-senior authors of the new paper.
More cautious researchers would have realized they were on the wrong track, says Rudolf Jaenisch, a
stem cell researcher at the Massachusetts Institute of Technology in Cambridge whose
lab spent 2 months trying to make STAP
cells and contributed data to the new paper.
Egg and sperm - like
cells have recently been derived from animal
stem cells, and this year the first mice were born from
lab - grown sperm.
For the purpose of additional experiments, the researchers generated myocardial
cells from embryonic
stem cells and human skin
cells, in collaboration with the
lab headed by Prof Dr Jürgen Hescheler at the University of Cologne.
Novitch's UCLA
lab group has likewise used its brain organoids to pinpoint additional receptors by which the virus may gain entry into neural
stem cells, and identified a few other drug leads for blocking infection.