Sentences with phrase «oxidative signaling pathways»

A fashionable contrary view has arisen: antioxidants not only don't help, they can do harm by interfering with oxidative signaling pathways.

Not exact matches

Analysis of signaling pathways that were affected pointed to changes in mitochondrial function and oxidative phosphorylation, consistent with a number of studies showing perturbations of these pathways in neurodegenerative disorders.

In Ames dwarrf, Snell Dwarf mice, Klotho mice, GHKO mice who have little IGF and GH; and live longer than wild - type; we see that indeed insulin and glucose / nutrient / energy pathways (which create oxidative stress through excessive nutrient via elevated glycation blood glucose creating high glycated albumin and hemoglobin), that aging is acted on by IGF through hormones, GFs, GHs, acting on insulin signals, which act on survival genes (DAF / SIRT / FOXO).

«They concluded that genetic differences and type of fat in the roundworm diet appears to be associated with longevity, and that the reason roundworms lived longer with MUFA might relate to less oxidative stress, or alteration in signalling pathways at cell level that improved their longevity.

Involvement of PI3K / PKG / ERK1 / 2 signaling pathways in cortical neurons to trigger protection by cotreatment of acetyl - L - carnitine and alpha - lipoic acid against HNE - mediated oxidative stress and neurotoxicity: implications for Alzheimer's disease.

Nrf2 / ARE Signaling Pathway: Key Mediator in Oxidative Stress and Potential Therapeutic Target in ALS.

The Nrf2 - ARE Signalling pathway: promising drug target to combat oxidative stress in neurodegenerative disorders.

Oxidative stress in tissue cells may trigger an inflammatory response by the NF - kappa B nuclear signaling pathway.

An Overview of the Primary Signaling Pathways Related to Exercise, Oxidative Stress and Antioxidant Intake Via Nutritional Habits and Supplementation