Sentences with phrase «oxidative stress play»

Mitochondrial dysfunction and oxidative stress play a huge role in declining egg quality, and these things can be slowed and improved with natural supplements.

also near misses like alberto salazar (heart attack) and grete waitz (not cardiac but died of cancer... did oxidative stress play a role?)

New evidence suggests that free radicals and oxidative stress play a role in the initiation of acne.

Current studies have demonstrated that the chronic endoplasmic reticulum stress and oxidative stress play an important role in development and progression of AP [4, 5].

Increased free radical induced oxidative stress plays a pivotal role in pathogenesis of many diseases including obesity, T2D and AP [7, 39 - 43] leading to macromolecular damage (DNA, protein and lipids), inflammation, ER stress and necrosis of acinar cells [44].

Oxidative stress plays significant roles in cancer, but also in Artherosclerosis, Arthritis and Cataract.

Sage is even hypothesized to confer protection against disease states where oxidative stress plays an etiological role, such as autoimmune disorders, neurodegenerative disease, and cancer (Garcia et al., 2016).

Oxidative stress plays a central role in the pathogenesis and progression of late microangiopathic complications (diabetic nephropathy) in diabetes mellitus.

It is postulated that the significant decrease in plasma thrombomodulin and failure of UAC to increase observed in the alpha - lipoic acid treated group is due to antioxidative effects of alpha - lipoic acid, and if so that oxidative stress plays a central role in the pathogenesis of diabetic nephropathy.

Oxidative Stress in Diabetes and Alzheimer's Disease J Alzheimers Dis 2009 (Apr); 16 (4): 763 — 774 Oxidative stress plays a major role in diabetes as well as in Alzheimer's disease and other related neurological diseases.

Effect of Alpha - lipoic Acid on the Progression of Endothelial Cell Damage and Albuminuria in Patients with Diabetes Mellitus: An Exploratory Study Diabetes Res Clin Pract 2001 (Jun); 52 (3): 175 — 183 Oxidative stress plays a central role in the pathogenesis and progression of late microangiopathic complications (diabetic nephropathy) in diabetes mellitus.

Not exact matches

Because oxidative stress is known to play a role in the development of some cancers, and pumpkin seeds are unique in their composition of antioxidant nutrients, it's not surprising to find some preliminary evidence of decreased cancer risk in association with pumpkin seed intake.

Decrease in oxidative stress has played a key role in many studies that show benefits of pumpkin seeds for diabetic animals.

The oxidative stress and resulting inflammation appear to play a role in the development of atherosclerosis (blocked arteries) and can make other health conditions worse, especially for people with existing cardiac or lung conditions including asthma.

«Another contribution of this study is that glia play an important protective role against oxidative stress in neurodegeneration,» Bellen said.

«Since mitochondria are the energy powerhouses of the cell, they're also the place where the most free radicals (which play a role in oxidative stress) are produced.

«Oxidative stress caused by exposure to air pollutants may therefore play a role in the development of insulin resistance.

Spaceflight exposes astronauts — and mice — to radiation, hypothermia, hypoxia and variations in gravity, all of which may play roles in tissue injury, and, in particular, oxidative stress.

In the summer of 2010, we posted an entry about a significant advance in basic mitochondrial biology that held within it a tantalizing promise: a potentially new approach to obviating the problem of age - related accumulation of mutations in mitochondrial DNA (mtDNA), which are widely suspected to play an important role in the age - related rise in oxidative stress, Parkinson's disease, and age - related muscle degeneration.

Certain particle compounds may directly generate ROS in vivo because of their surface chemistry (eg, metals, organic compounds, and semiquinones) or after bioactivation by cytochrome P450 systems (eg, polycyclic aromatic hydrocarbon conversion to quinones).6, 290 a, 290 b A particle surface or anions present on otherwise more inert particles may disrupt iron homeostasis in the lung and thereby also generate ROS via Fenton reactions.291 Other PM constituents may do so indirectly by the upregulation of endogenous cellular sources (eg, nicotinamide adenine dinucleotide phosphate [NADPH]-RRB- oxidase) 292,293 or by perturbing organelle function (eg, mitochondria) by taken - up PM components.261 Particle stimulation of irritant and afferent ANS fibers may also play a role in local and systemic oxidative stress formation.294 Given the rich antioxidant defenses in the lung fluid, secondarily generated oxidization products of endogenous molecules (eg, oxidized phospholipids, proteins) or a reduction in endogenous antioxidants per se may be responsible at least in part for the state of oxidative stress in the lungs (along with instigating the subsequent cellular responses) rather than ROS derived directly from PM and its constituents.

Raspberry phytonutrients have been shown to play an important role in lowering oxidative stress, reducing inflammation, and thereby altering the development or reproduction of cancer cells.

Aging of the retina is linked to increased oxidative damage levels, and oxidative stress is believed to play a crucial part in the development of age - related macular degeneration.

In addition to its role in the immune system, zinc also reduces oxidative stress, plays a structural role by stabilizing proteins, regulates the expression of many genes, and drives hundreds of chemical reactions in the body.

Oxidative stress and inflammation both play a role in diabetes complications, but milk thistle, and herbal drug, has been shown to have anti-inflammatory and antioxidant properties.

As an antioxidant, zinc plays a role in helping to prevent cell damage and inflammation caused by oxidative stress.

As the body's largest organ, skin plays a crucial role in protecting against oxidative stressors such as UV radiation, x-rays, cigarette smoke, air - borne allergens, mold and other toxins, industrial chemicals, pollution, emotional stress, and poor diet — all of which contribute to aging and disease and a lot of which we encounter everyday.

Oxidative stress on brain cells likely plays a role, too.

Probably glutathione's most important function is the role it plays in binding to, and neutralizing, dangerous free radicals — which otherwise can create the oxidative stress that destroys tissue and sets the stage for disease.

In case of oxidative stress in the body, the buildup of damaging free radicals have a known role to play in causing insulin resistance and exaggerating diabetes related complications.

These antioxidants play an important role in protecting the cells from oxidative stress and reducing the risk of heart diseases, thus preventing the development of serious illnesses.

These two conventional nutrients play a critical role in our body's regulation of oxygen metabolism, and they are widely known for their role in helping lower our risk of oxidative stress.

Oxidative stress is known to play a role in a long list of serious chronic conditions, including Alzheimer's, arthritis, cancer, diabetes, autoimmune diseases, Parkinson's, macular degeneration, and glaucoma.

In recent years, researchers have shifted their focus to oxidative stress, which plays a role in the pathogenesis of many chronic diseases, including heart disease.

Because oxidative stress is known to play a role in the development of some cancers, and pumpkin seeds are unique in their composition of antioxidant nutrients, it's not surprising to find some preliminary evidence of decreased cancer risk in association with pumpkin seed intake.

Clinical studies have shown these powerful antioxidants to be anti-inflammatory, protect the heart and brain, and play a fundamental role in reducing oxidative stress.

Berries, especially blue - berries and blackberries, are helpful in fighting any disease in which oxidative stress and inflammation play a role, including arthritis, allergies, and cancer.

Oxidative damage to cells (oxidative stress) and chronic inflammation go hand in hand and both are thought to play a parOxidative damage to cells (oxidative stress) and chronic inflammation go hand in hand and both are thought to play a paroxidative stress) and chronic inflammation go hand in hand and both are thought to play a part in CKD.