"Oxide synthase" refers to an enzyme that plays a role in creating or producing a specific type of compound called an oxide.
Full definition
Chlorogenic acids may exert protective effects against metabolic syndrome risk through their antioxidant properties, in particular toward vascular endothelial cells, in which nitric oxide production may be enhanced, by promoting endothelial nitric
oxide synthase expression.
The study noted that there was no increase in the nitric
oxide synthase levels in the control group of hamsters that did not undergo this sauna therapy.
AgmaMAX ® -(Agmatine Sulfate)- a metabolite of arginine that plays a role in the production of nitric oxide by the modulation of nitric
oxide synthase which are enzymes that play a role in nitric oxide production *.
Journal of Molecular Endocrinology, 2004, 33:797 - 803, «High glucose decreases intracellular glutathione concentrations and upregulates inducible nitric
oxide synthase gene expression in intestinal epithelial cells»
The researchers say that blocking IL - 1 halted a cascade of inflammatory responses that would otherwise lead to the activation of neuronal nitric
oxide synthase in the fetal brain, an enzyme implicated in neurotoxicity.
Along with Factor 2's powerful amino acids, vitamin C and calcium work in tandem to help increase the amount of
nitric oxide synthase enzyme in your body, catalyzing the NO reaction and delivering a sustained release.
In animal studies, activation of nuclear factor - kappa B (NF - kB); activation of inducible nitric
oxide synthase (iNOS), and cyclooxygenase - 2 (COX - 2); and formation of malondialdehyde (MDA) have all be shown to get reduced following consumption of either sweet potato or its color - containing extracts.
In wild - type mouse blood vessels, estrogen attenuates vasoconstriction by an ERβ - mediated increase in inducible nitric
oxide synthase expression.
The project was any enzymologist's dream: nitric
oxide synthase.
Neufeld's group recently found that the enzyme nitric
oxide synthase 2 (NOS - 2), which produces toxic levels of the gas nitric oxide, is active in the eyes of rats that have their eyes» drainage channels blocked, causing an artificial form of glaucoma.
The study, which appears online October 29 in the journal Science Signaling, describes a previously uncharacterized interaction between GRK2 and an enzyme called endothelial nitric
oxide synthase (eNOS), in which the two enzymes attempt to block one another's activity, with different outcomes on heart function.
The presence of the enzyme nitric
oxide synthase was used to identify an especially potent wake - promoting group of neurons, but their functions still depend on glutamate release.
Pictured are isolated adult mouse cardiomyocytes labeled for dystrophin (red), neuronal nitric
oxide synthase (nNOS)(green), and nuclei (blue).
Now, an international team of scientists has shown that increased resistance to bacterial pneumonia in female mice is linked to the enzyme nitric
oxide synthase 3 (NOS3).
mRNAs and protein expression for HIF - 1α, VEGF, nitric
oxide synthase, and glutamate receptor subunits NMDAR1, GluR2, GluR3 were each found to be upregulated at 3 h and 24 h, but all returned to control levels by 14 days.
Two of these SNPs are within a single gene, which codes for the enzyme nitric
oxide synthase 2 (NOS2).
In diabetic rat models, female mesenteric arteries show greater abnormal vascular responses demonstrated by greater impairment of acetycholin - induced relaxation and an increased expression of endothelial nitric
oxide synthase.
[19] One of the effectors of microglial - mediated neuronal death is inducible nitric
oxide synthase (iNOS), which is induced in PD brain and inflammatory - biased (M1) macrophages (including activated microglia) and reactive astrocytes.
Genome - wide identification of Drosophila Hb9 targets reveals a pivotal role in directing the transcriptome within eight neuronal lineages, including activation of Nitric
Oxide Synthase and FoxD.
One of the key processes involved in secondary damage is iNOS (Nitric
oxide synthase)- mediated cell damage, through the generation of reactive nitrogen species peroxinitrates.
The pathogen - inducible nitric
oxide synthase (iNOS) in plants is a variant of the p protein of the glycine decarboxylase complex (Retraction of vol 113, pg 469, 2003)
Nitric oxide (NO) is endogenously synthesized by nitric
oxide synthases (NOSs) which convert L - arginine to L - citrulline and NO in the presence of oxygen and several cofactors.
The Pathogen - Inducible Nitric
Oxide Synthase (iNOS) in Plants Is a Variant of the P Protein of the Glycine Decarboxylase Complex
At Scripps, Crane studied metalloenzymes and applied structural biology techniques to trying to understand the catalytic mechanisms of two types of redox enzymes, sulfite reductases and nitric
oxide synthases.
Galanin enhances systemic glucose metabolism through enteric Nitric
Oxide Synthase - expressed neurons
Dr. Nathan's extensive work on macrophage and neutrophil activation / deactivation, the respiratory burst and inducible nitric
oxide synthase (iNOS), has led to current projects that focus on inflammation and macrophage interactions with Mycobacterium tuberculosis (Mtb).
Because Dr. Nisoli and others had found that endothelial nitric
oxide synthase (eNOS, also called Nos3) is associated with the life span - extending effects of calorie restriction, mitochondrial biogenesis, and SIRT1 expression, he and his team investigated the relationship between the BCAAem and eNOS.
Their antioxidant and anti-inflammatory activities are largely due to their abilities to scavenge the reactive oxygen species (ROS) and improvement of antioxidant status by attenuating the activity of NF - κB and suppressing the expression of several inflammatory cytokines and chemokines including monocyte chemotactic protein - 1 (MCP - 1), nitric
oxide synthase, cyclooxygenases, lipoxygenases, cellular adhesion molecules, tumor necrosis factor and interleukins.
If the dosages are too high (subjected to inter-individual variability factor) the excessive dosages can actually suppress the endothelial nitric
oxide synthase (eNOS) levels by activating a feedback mechanism the body employs to mitigate the excessive formation of nitric oxide.
National Center for Biotechnical Information, published a PubMed.gov study showing that when hamsters with cardiovascular heart problems underwent four weeks of far infrared sauna therapy, the levels of nitric
oxide synthase (eNOS) in their bodies increased.
This is significant since nitric
oxide synthase is known to lower blood pressure.
These beneficial effects result from α - tocopherol's inhibition of the PKC - dependent phosphorylation of the endothelial form of nitric
oxide synthase (eNOS), thus preventing a reduction in eNOS» catalytic activity.1
For instance, exposure to light causes release of NO from mitochondria and also an increase in NO levels due to photoactivation of nitric
oxide synthase.
The final step in nitric oxide formation is the conversion of l - arginine to NO using enzymes called nitric
oxide synthases.
Repeated sauna therapy increases arterial endothelial nitric
oxide synthase expression and nitric oxide production in cardiomyopathic hamsters
Phrases with «oxide synthase»