Role of neuronal nitric -
oxide synthase in estrogen - induced relaxation in rat resistance arteries.
Nuclear factor kappa - B mediates selective induction of neuronal nitric
oxide synthase in astrocytes during low - level inflammatory stimulation with MPTP.
The researchers say that blocking IL - 1 halted a cascade of inflammatory responses that would otherwise lead to the activation of neuronal nitric
oxide synthase in the fetal brain, an enzyme implicated in neurotoxicity.
Not exact matches
In animal studies, activation of nuclear factor - kappa B (NF - kB); activation of inducible nitric
oxide synthase (iNOS), and cyclooxygenase - 2 (COX - 2); and formation of malondialdehyde (MDA) have all be shown to get reduced following consumption of either sweet potato or its color - containing extracts.
In wild - type mouse blood vessels, estrogen attenuates vasoconstriction by an ERβ - mediated increase in inducible nitric oxide synthase expressio
In wild - type mouse blood vessels, estrogen attenuates vasoconstriction by an ERβ - mediated increase
in inducible nitric oxide synthase expressio
in inducible nitric
oxide synthase expression.
Neufeld's group recently found that the enzyme nitric
oxide synthase 2 (NOS - 2), which produces toxic levels of the gas nitric
oxide, is active
in the eyes of rats that have their eyes» drainage channels blocked, causing an artificial form of glaucoma.
The study, which appears online October 29
in the journal Science Signaling, describes a previously uncharacterized interaction between GRK2 and an enzyme called endothelial nitric
oxide synthase (eNOS),
in which the two enzymes attempt to block one another's activity, with different outcomes on heart function.
Differential inducible nitric
oxide synthase expression
in systemic and pulmonary vessels after endotoxin.
In diabetic rat models, female mesenteric arteries show greater abnormal vascular responses demonstrated by greater impairment of acetycholin - induced relaxation and an increased expression of endothelial nitric
oxide synthase.
Genome - wide identification of Drosophila Hb9 targets reveals a pivotal role
in directing the transcriptome within eight neuronal lineages, including activation of Nitric
Oxide Synthase and FoxD.
One of the key processes involved
in secondary damage is iNOS (Nitric
oxide synthase)- mediated cell damage, through the generation of reactive nitrogen species peroxinitrates.
The pathogen - inducible nitric
oxide synthase (iNOS)
in plants is a variant of the p protein of the glycine decarboxylase complex (Retraction of vol 113, pg 469, 2003)
Nitric
oxide (NO) is endogenously synthesized by nitric
oxide synthases (NOSs) which convert L - arginine to L - citrulline and NO
in the presence of oxygen and several cofactors.
The Pathogen - Inducible Nitric
Oxide Synthase (iNOS)
in Plants Is a Variant of the P Protein of the Glycine Decarboxylase Complex
Abbreviations: Aβ, amyloid β - peptide; AD, Alzheimer's disease; ALS, amyotrophic lateral sclerosis; Ambra1, activating molecule
in Beclin -1-regulated autophagy; AMPK, AMP - activated protein kinase; APP, amyloid precursor protein; AR, androgen receptor; Atg, autophagy - related; AV, autophagic vacuole; Bcl, B - cell lymphoma; BH3, Bcl - 2 homology 3; CaMKKβ, Ca2 + - dependent protein kinase kinase β; CHMP2B, charged multivesicular body protein 2B; CMA, chaperone - mediated autophagy; 2 ′ 5 ′ ddA, 2 ′, 5 ′ - dideoxyadenosine; deptor, DEP - domain containing mTOR - interacting protein; DRPLA, dentatorubral pallidoluysian atrophy; 4E - BP1, translation initiation factor 4E - binding protein - 1; Epac, exchange protein directly activated by cAMP; ER, endoplasmic reticulum; ERK1 / 2, extracellular - signal - regulated kinase 1/2; ESCRT, endosomal sorting complex required for transport; FAD, familial AD; FDA, U.S. Food and Drug Administration; FIP200, focal adhesion kinase family - interacting protein of 200 kDa; FoxO3, forkhead box O3; FTD, frontotemporal dementia; FTD3, FTD linked to chromosome 3; GAP, GTPase - activating protein; GR, guanidine retinoid; GSK3, glycogen
synthase kinase 3; HD, Huntington's disease; hiPSC, human induced pluripotent stem cell; hVps, mammalian vacuolar protein sorting homologue; IKK, inhibitor of nuclear factor κB kinase; IMPase, inositol monophosphatase; IP3R,
Ins (1,4,5) P3 receptor; I1R, imidazoline - 1 receptor; JNK1, c - Jun N - terminal kinase 1; LC3, light chain 3; LD, Lafora disease; L - NAME, NG - nitro - L - arginine methyl ester; LRRK2, leucine - rich repeat kinase 2; MIPS, myo - inositol -1-phosphate
synthase; mLST8, mammalian lethal with SEC13 protein 8; MND, motor neuron disease; mTOR, mammalian target of rapamycin; mTORC, mTOR complex; MVB, multivesicular body; NAC, N - acetylcysteine; NBR1, neighbour of BRCA1 gene 1; NOS, nitric
oxide synthase; p70S6K, ribosomal protein S6 kinase - 1; PD, Parkinson's disease; PDK1, phosphoinositide - dependent kinase 1; PE, phosphatidylethanolamine; PI3K, phosphoinositide 3 - kinase; PI3KC1a, class Ia PI3K; PI3KC3, class III PI3K; PI3KK, PI3K - related protein kinase; PINK1, PTEN - induced kinase 1; PKA, protein kinase A; PLC, phospholipase C; polyQ, polyglutamine; PS, presenilin; PTEN, phosphatase and tensin homologue deleted from chromosome 10; Rag, Ras - related GTP - binding protein; raptor, regulatory - associated protein of mTOR; Rheb, Ras homologue enriched
in brain; rictor, rapamycin - insensitive companion of mTOR; SBMA, spinobulbar muscular atrophy; SCA, spinocerebellar ataxia; SLC, solute carrier; SMER, small - molecule enhancer of rapamycin; SMIR, small - molecule inhibitor of rapamycin; SNARE, N - ethylmaleimide - sensitive factor - attachment protein receptor; SOD1, copper / zinc superoxide dismutase 1; TFEB, transcription factor EB; TOR, target of rapamycin; TSC, tuberous sclerosis complex; ULK1, UNC -51-like kinase 1; UVRAG, UV irradiation resistance - associated gene; VAMP, vesicle - associated membrane protein; v - ATPase, vacuolar H + - ATPase; Vps, vacuolar protein sorting
National Center for Biotechnical Information, published a PubMed.gov study showing that when hamsters with cardiovascular heart problems underwent four weeks of far infrared sauna therapy, the levels of nitric
oxide synthase (eNOS)
in their bodies increased.
For instance, exposure to light causes release of NO from mitochondria and also an increase
in NO levels due to photoactivation of nitric
oxide synthase.
(8)
In another study, the anti-inflammatory properties of the active ingredient in schisandra, schisandrin, were shown to result from the inhibition of nitric oxide (NO) production, prostaglandin E2 (PGE2) release, cyclooxygenase - 2 (COX - 2) and inducible nitric oxide synthase (iNOS) expressio
In another study, the anti-inflammatory properties of the active ingredient
in schisandra, schisandrin, were shown to result from the inhibition of nitric oxide (NO) production, prostaglandin E2 (PGE2) release, cyclooxygenase - 2 (COX - 2) and inducible nitric oxide synthase (iNOS) expressio
in schisandra, schisandrin, were shown to result from the inhibition of nitric
oxide (NO) production, prostaglandin E2 (PGE2) release, cyclooxygenase - 2 (COX - 2) and inducible nitric
oxide synthase (iNOS) expression.
Even more encouraging is evidence that polyphenols
in olive oil can interact with a hereditary gene variant of endothelial nitric
oxide synthase (the NOS3 Glu298Asp polymorphism, which is a risk factor for hypertension and coronary artery disease), to improve endothelial function after meals.19 So, even if genetics are not
in your favor, olive oil may help.»
Even though oral arginine can be completely ineffective
in small doses, if the dosages are too high (depending on the individual recipient) arginine can actually disrupt endothelial nitric
oxide synthase (eNOS) levels by activating a feedback mechanism which the body utilizes to mitigate excessive formation of nitric
oxide (NO).
AgmaMAX ® -(Agmatine Sulfate)- a metabolite of arginine that plays a role
in the production of nitric
oxide by the modulation of nitric
oxide synthase which are enzymes that play a role
in nitric
oxide production *.