Sentences with phrase «oxygen radical production»

In support of this concept, we have shown that mtDNA mutations accumulate in proportion to life span in several animals, that increasing mitochondrial anti-oxidant defense systems extends lifespan, that ancient human mtDNA variants that modify energy production and oxygen radical production can modulate longevity and risk for neurodegenerative diseases, and that patients with the neurodegenerative disease, Alzheimer Disease, have increased mtDNA mutations.

Not exact matches

At the hearing, Carpenter suggested that cell phones may increase the brain's production of reactive forms of oxygen called free radicals, which can interact with and damage DNA.

One possibility, advanced by the Wisconsin team, is that restricting food consumption reduces the production of tissue - damaging oxygen free radicals that are a byproduct of food metabolism.

The Einstein team suspected that cysteine was helping to kill TB bacteria by acting as a «reducing agent» that triggers the production of reactive oxygen species (sometimes called free radicals), which can damage DNA.

They describe that the alterations are due to a disproportionate, though transitory, increase in the production of radical oxygen species (ROS) in the hypothalamus.

In one recent study Achyranthes bidentata polypeptides (ABPP) separated from the aqueous extract of Achyranthes bidentata were shown to reverse production of intracellular radical oxygen species (ROS) and confer neuroprotective effects on NMDA receptors.

All of these happen because the free radicals and reactive oxygen species produced caused significant damage to the thyroid and reduced thyroid hormone production.

The oxygen you breathe can also contribute to the production of free radicals.

Energy metabolism and the production of Reactive Oxygen Species (very small molecules that can result in significant damage to cell structures, of which include oxygen ions, free radicals and peroxides) are thought to underpin many nuerodegenerative disorders, and creatine is thought to enhance the brains ability to survive the metabolic and physical trauma associated with these condiOxygen Species (very small molecules that can result in significant damage to cell structures, of which include oxygen ions, free radicals and peroxides) are thought to underpin many nuerodegenerative disorders, and creatine is thought to enhance the brains ability to survive the metabolic and physical trauma associated with these condioxygen ions, free radicals and peroxides) are thought to underpin many nuerodegenerative disorders, and creatine is thought to enhance the brains ability to survive the metabolic and physical trauma associated with these conditions.

Superoxide dismutase (SOD) is found inside the body's mitochondria (the oxygen - based energy factories inside most of our cells) where it provides protection against damage from the free radicals produced during energy production.

In the process of energy production, single electrons escape from the «factory line» and react with oxygen molecules to form free radicals such as peroxide and superoxide.

Oxidative stress describes the state of the body in which the production of reactive oxygen species (ROS), including free radicals, overwhelms the body's antioxidant defences.Our body tries to maintain a constant balance between free radicals and antioxidants.

Generation of reactive oxygen species, or free radicals such as superoxide and hydrogen peroxide, is a normal byproduct of metabolism, but can damage cellular machinery when excessive and impair the production of cellular energy, which becomes a vicious cycle as energy - intensive repair processes become untenable (25, 26).

If balls out training increases the production of damaging oxygen radicals than it makes perfect sense to limit oxidation as much as possible, right?

Similarly, a problem with antioxidant production can result in the buildup of reactive oxygen and nitrogen species, otherwise termed «free radicals», in the mitochondria.

Much like rust, this is a continuous wear and tear biochemical reaction in our cells producing free radicals (a by - product of oxygen - based energy - production processes).

So, the thinking is that lower methionine intake leads to less free radical production — the so - called «reactive oxygen species,» which slows the rate of DNA damage, which then would slow the rate of DNA mutation, slowing the rate of aging and disease — thereby potentially increasing our lifespan.

The therapeutic dotential of dietary precursor modulation by a fish - oil - supplemented diet (n - 3 fatty acids), such as eicosapentaenoic acid (C20: 5,n - 3) and docosahexaenoic acid (C22: 6,n - 3) in the therapy of ulcerative colitis has been shown to result in a 35 % to 50 % decrease in neutrophil production of LTB4.28 Significant improvement in symptoms and histologic appearance of the rectal mucosa has been observed in several small series of patients with Crohn's disease and ulcerative colitis given fish oil at 3 to 4 g daily for 2 to 6 months in uncontrolled studies.29 However, a larger, randomized, double - blind trial comprising 96 patients with ulcerative colitis failed to reveal any benefit in remission maintenance or treatment of relapse on 4.5 g of eicosapentaenoic acid daily, despite a significant reduction in LTB4 synthesis by blood peripheral polymorphonuclear cells.30 It should be emphasized, however, that the anti-inflammatory actions of the fish oils, in addition to inhibition of LTB4, include suppression of IL - 1 and platelet activating factor synthesis and scavenging of free oxygen radicals.30 The impact of increased lipid peroxidation after fish oil supplementation should be considered when altering the n - 6: n - 3 fatty acid ratio.31 Antioxidant supplementation may be able to counteract the potentially adverse effects of n - 3 fatty acids.