Sentences with phrase «oxygen species production»

... I'm blasting the air I'm breathing with a NanoVi Eng3, which enhances DNA repair and good reactive oxygen species production...

It also works on the mitochondria to ramp up the reactive oxygen species production in damaged cells, which takes the stress off healthy cells.

[1] Ketogenic diet benefits body composition and well - being but not performance in a pilot case study of New Zealand endurance athletes https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506682 [2] Ketogenic low - carbohydrate diets have no metabolic advantage over nonketogenic low - carbohydrate diets https://academic.oup.com/ajcn/article/83/5/1055/4649481 [3] Energy expenditure and body composition changes after an isocaloric ketogenic diet in overweight and obese men https://academic.oup.com/ajcn/article/104/2/324/456464 [4] Ketones block amyloid https://www.ncbi.nlm.nih.gov/pubmed/26923399 [5] Ketones Inhibit Mitochondrial Production of Reactive Oxygen Species Production Following Glutamate Excitotoxicity by Increasing NADH Oxidation https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1865572/ [6] The ketogenic diet may have mood - stabilizing properties https://www.ncbi.nlm.nih.gov/pubmed/11918434 [7] The antidepressant properties of the ketogenic diet http://www.ncbi.nlm.nih.gov/pubmed/15601609

Both factors may elicit a sympathetic and hypothalamic — pituitary — adrenal (HPA) axis response, which drive increased systemic reactive oxygen species production, chronic inflammation, and a metabolic substrate shift toward carbohydrate and away from fat oxidation, manifesting in an array of signs and symptoms often labeled as the overtraining syndrome.16

In vitro, IF pancreatic islets had increased insulin secretion, glucose metabolism and net reactive oxygen species production, while decreased their mass.

THE PEAK OF OXYGEN CONSUMPTION AT THE TIME OF SPERM PENETRATION IS ASSOCIATED WITH AN INCREASE IN REACTIVE OXYGEN SPECIES PRODUCTION IN BOVINE ZYGOTES.

The expression of micro-RNA miR - 663 was induced by mitochondrial reactive oxygen species production, an apoptotic signal and oxidative stress response, and miR - 663 induced the expression of nuclear - encoded mitochondrial respiratory chain subunits.

The particles carry RNA that shut off reactive oxygen species production.

Not exact matches

In the case of cisplatin - induced hearing loss, kenpaullone appears to protect hair cells by preventing CDK2 from stimulating the production of toxic reactive oxygen species from the cells» mitochondria.

Mitochondria help injured muscle cells (myofibers) repair by soaking up calcium that enters from the site of injury and using it to trigger increased production of reactive oxygen species.

The cells» survival relies on a delicate balance between energy and reactive oxygen species (ROS) production.

«Energy production can also generate reactive chemical species — often referred to as «reactive oxygen species» or «oxidants» — as by - products, which can be damaging to cells.

Oxidative states are generally considered to be indicative of cellular stress; however, cells inherently release harmful reactive oxygen species during energy production, neutralized by intracellular antioxidative buffering systems.

The Einstein team suspected that cysteine was helping to kill TB bacteria by acting as a «reducing agent» that triggers the production of reactive oxygen species (sometimes called free radicals), which can damage DNA.

Also, in both cell culture and a mouse model of the condition, blocking the excessive splintering reduced production of reactive oxygen species, a potentially harmful byproduct of metabolism, as well as cell death.

Sevoflurane - induced cardioprotection depends on PKC - α activation via production of reactive oxygen species.

Hepatitis C Virus Regulates Transforming Growth Factor [beta] 1 Production Through the Generation of Reactive Oxygen Species in a Nuclear Factor [kappa] B - Dependent Manner.

The basic metabolism of a cell generates reactive oxygen species (ROS) which oxidize cellular lipids, proteins, and DNA leading to production of reactive electrophiles which can lead to deleterious consequences if not eliminated [1].

This primary response involves the production of reactive oxygen species (ROS), which are molecules that can act like tiny bombs when released by the plant cell at the offending pathogen.

In addition, the loss of Ripk2 has been demonstrated to result in the inability of cells to carry out mitophagy, leading to enhanced mitochondrial production of superoxide / reactive oxygen species and accumulation of damaged mitochondria that will trigger a caspase 1 — dependent inflammasome activation (Lupfer et al., 2014).

They describe that the alterations are due to a disproportionate, though transitory, increase in the production of radical oxygen species (ROS) in the hypothalamus.

Research had shown that increased mitochondrial activity may be at least partly responsible for extending the life span of yeast, roundworms, fruit flies and some mammals — perhaps by reducing the production of disease - causing reactive oxygen species (ROS).

«Mitochondrial Production of Reactive Oxygen Species and Incidence of Age - Associated Lymphoma in OF1 Mice: Effect of Alternate - Day Fasting,» Mechanisms of Ageing and Development, 126 (11), 1185 - 1191.

These powerhouse organelles are major sites of oxidative stress due to the high production of reactive oxygen species ROS (reactive oxygen species) and RNS (reactive nitrogen species).

In one recent study Achyranthes bidentata polypeptides (ABPP) separated from the aqueous extract of Achyranthes bidentata were shown to reverse production of intracellular radical oxygen species (ROS) and confer neuroprotective effects on NMDA receptors.

All of these happen because the free radicals and reactive oxygen species produced caused significant damage to the thyroid and reduced thyroid hormone production.

(7) In related studies extracts of Dong quai have been shown to support health by exerting inflammation - modulating effects on the production of excess nitric oxide (NO) and reactive oxygen species (ROS).

The resulting drop in glutathione production and intracellular glutathione concentrations compromises the mitochondria's ability to scavenge reactive oxygen species (ROS), producing a vicious cycle that drives the progressive increase in ROS - mediated structural damage and its corollary, the progressive decline in energy production and repair that accompanies aging.

(15) In a second study, an active ingredient present in the Salvia miltiorrhiza root was found to have inflammation - modulating effects on TNF - alpha - induced production of reactive oxygen species (ROS), demonstrating a potential role in supporting endothelial and vascular health.

The immune defense against these infections is glucose - dependent (as it relies on production of reactive oxygen species using glucose) and thyroid hormone - dependent (as thyroid hormone drives not only glucose availability, but also the availability of iodine for the myeloperoxidase pathway).

Researchers believe that the antioxidant properties of tocotrienol inhibit the production of reactive oxygen species (ROS).

Pretreatment of cells with Cy -3-G reduced the intracellular production of reactive oxygen species, the activation of JNK, and attenuated H (2) O (2)- or TNF - alpha - induced insulin resistance in a dose - dependent manner.

Energy metabolism and the production of Reactive Oxygen Species (very small molecules that can result in significant damage to cell structures, of which include oxygen ions, free radicals and peroxides) are thought to underpin many nuerodegenerative disorders, and creatine is thought to enhance the brains ability to survive the metabolic and physical trauma associated with these condiOxygen Species (very small molecules that can result in significant damage to cell structures, of which include oxygen ions, free radicals and peroxides) are thought to underpin many nuerodegenerative disorders, and creatine is thought to enhance the brains ability to survive the metabolic and physical trauma associated with these condioxygen ions, free radicals and peroxides) are thought to underpin many nuerodegenerative disorders, and creatine is thought to enhance the brains ability to survive the metabolic and physical trauma associated with these conditions.

Known as «delayed onset muscle soreness» (DOMS), we typically experience these pains when eccentric muscle activity is involved and the contracting muscles are forcibly lengthened.1 This mechanical stress triggers an inflammatory response and the production of reactive oxygen species (ROS).

Flavonoids have been shown to inhibit the production of ROS (Reactive Oxygen Species), the activity of the ROS generating enzymes MPO and NADPH oxidase, and several signal transducing enzymes involved in the cell activation in neutrophils.

We show that increased mitochondrial oxidation of succinate via succinate dehydrogenase (SDH) and an elevation of mitochondrial membrane potential combine to drive mitochondrial reactive oxygen species (ROS) production.»

Oxidative stress describes the state of the body in which the production of reactive oxygen species (ROS), including free radicals, overwhelms the body's antioxidant defences.Our body tries to maintain a constant balance between free radicals and antioxidants.

LTB4 increases edema and chemotaxis, induces release of lysosomal enzymes, increases reactive oxygen species, and enhances production of the cytokines TNF - α, IL - 1, and IL - 6.»

Generation of reactive oxygen species, or free radicals such as superoxide and hydrogen peroxide, is a normal byproduct of metabolism, but can damage cellular machinery when excessive and impair the production of cellular energy, which becomes a vicious cycle as energy - intensive repair processes become untenable (25, 26).

It has been known for quite some time that intense exercise increases the production of potentially toxic reactive oxygen species (ROS), which have been linked to aging and most chronic diseases, one way or another.

Similarly, a problem with antioxidant production can result in the buildup of reactive oxygen and nitrogen species, otherwise termed «free radicals», in the mitochondria.

Intracellular oxidative stress arises due to the imbalance in the production of reactive oxygen / reactive nitrogen species and cellular antioxidant defense mechanisms.

So, the thinking is that lower methionine intake leads to less free radical production — the so - called «reactive oxygen species,» which slows the rate of DNA damage, which then would slow the rate of DNA mutation, slowing the rate of aging and disease — thereby potentially increasing our lifespan.

For example, KBs were recently reported to act as neuroprotective agents by raising ATP levels and reducing the production of reactive oxygen species in neurological tissues, 80 together with increased mitochondrial biogenesis, which may help to enhance the regulation of synaptic function.80 Moreover, the increased synthesis of polyunsaturated fatty acids stimulated by a KD may have a role in the regulation of neuronal membrane excitability: it has been demonstrated, for example, that polyunsaturated fatty acids modulate the excitability of neurons by blocking voltage-gated sodium channels.81 Another possibility is that by reducing glucose metabolism, ketogenic diets may activate anticonvulsant mechanisms, as has been reported in a rat model.82 In addition, caloric restriction per se has been suggested to exert neuroprotective effects, including improved mitochondrial function, decreased oxidative stress and apoptosis, and inhibition of proinflammatory mediators, such as the cytokines tumour necrosis factor - α and interleukins.83 Although promising data have been collected (see below), at the present time the real clinical benefits of ketogenic diets in most neurological diseases remain largely speculative and uncertain, with the significant exception of its use in the treatment of convulsion diseases.

Resveratrol was found to induce antioxidant enzymes, including superoxide dismutase (SOD), thioredoxin, glutathione peroxidase - 1, heme oxygenase - 1, and catalase, and / or inhibit reactive oxygen species (ROS) production by nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (NOX)(21).