Sentences with phrase «paclitaxel induces»
Not exact matches
Paclitaxel - induced peripheral neuropathy affects the majority of treated patients; however, those who are most severely affected (about 30 percent) have to terminate chemotherapy or reduce the dose because of this condition, which can impact cancer survival.
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Oral administration of mebendazole in mice elicited a strong antitumor effect in a subcutaneous model and reduced lesions in experimentally induced lung metastasis without any toxicity when compared with paclitaxel - treated mice [9,20].
Pharmacological characterization of paclitaxel - induced neuropathic pain in rats.
In addition, chronic oral administration of gabapentin (from day 24 — day 44) also reversed paclitaxel - induced mechanical hyperalgesia when administered at 100mg / kg but not 50 mg / kg.
Acute, oral administration of gabapentin (100 mg / kg) reversed mechanical induced allodynia in paclitaxel - injected rats tested on day 23 and on day 35.