Moreover, the combination can reduce the dosage of the opioid needed to be effective, according to a team of
pain researchers at Indiana University.
«Males can be perceived as dangerous, and stress can muffle pain responses,» says Jeffrey Mogil, the study's lead author and
a pain researcher at McGill University in Montreal.
This apparent effect is «something that people have been whispering about at meetings for years,» says lead author Jeffrey Mogil,
a pain researcher at McGill University in Montreal, Canada.
«When I go to work every day, I don't think about opioid - induced hyperalgesia,» says Gary Bennett,
a pain researcher at the University of California in San Diego.
If inflammation turns out to be a key driver of OIH, it might also point the way to a better test for the effect, says Lesley Colvin,
a pain researcher at the University of Edinburgh.
Not exact matches
The
researchers also looked
at the effect of other variables on chronic
pain including surgical technique,
pain in the first 24 - 72 hours, maternal education and occupation, and anxiety during breastfeeding.
The
researchers found that moms who disliked breastfeeding or experienced
pain while breastfeeding during the first two weeks of their baby's life were
at a higher risk for experiencing postpartum depression by the time their baby was two months old.
For this study,
researchers looked
at whether BNP played a role in transmitting acute, inflammatory or neuropathic
pain in mice.
On reanalysing data from the group's past studies, such as on
pain sensitivity to hot water, the
researchers found that mice tested by men showed lower baseline
pain sensitivity than mice tested by women.The work indirectly demonstrates potential effects on nearly any kind of medical research, says Joseph Garner, who studies mouse behavior and well - being
at Stanford University in California.
Researchers at the Veterans Health Administration conducted a systematic review of 67 published studies to determine the effectiveness of strategies to reduce or discontinue long - term opioid therapy prescribed for chronic
pain and the effect of dose reduction or discontinuation on important patient outcomes.
Researchers at Johns Hopkins Bayview Medical Center used two relatively simple tactics to significantly reduce the number of unnecessary blood tests to assess symptoms of heart attack and chest
pain and to achieve a large decrease in patient charges.
The
researchers used several measures to determine whether the stem cells were effective in alleviating neuropathic
pain and bladder dysfunction
at six months.
Some of the best support for this contention came in 2012, when
researchers at Memorial Sloan Kettering Cancer Center and their colleagues published a meta - analysis of 29 studies involving nearly 18,000 patients, which found that traditional acupuncture produced a somewhat greater reduction in
pain than placebo or sham acupuncture.
In a new study,
researchers based
at Osaka University reported on their use of brain - machine interface (BMI) training with a robotic hand on 10 phantom limb patients to investigate the association between changes in symptomatic
pain and cortical currents during phantom hand movements.
A joint study by
researchers at the University of California, San Diego and the University of Toronto has found that a computer system spots real or faked expressions of
pain more accurately than people can.
Researchers at Georgetown University Medical Center recently discovered that these drugs also interact with specific proteins on the surfaces of nerve cells — which could also lead to increased
pain when patients wake up.
Yesterday,
at the annual American College of Rheumatology meeting in Atlanta, Ga.,
researchers announced the results of a double - blind, randomized trial in more than 600 patients: tasocitinib eased
pain and inflammation in 65.7 percent of those who received the highest dose of the drug, whereas only 26.7 percent of those who received a placebo reported relief.
A team of
researchers at the University of Colorado School of Medicine and the VA Eastern Colorado Health Care System recently surveyed patients to understand barriers to reducing the use of opioids to manage chronic
pain.
From the beginning, the
researchers took great
pains to select birds only for their behavior: Jungle fowl were tested for tameness
at 12 weeks old, before they reached sexual maturity.
This finding led by a team of
researchers at McGill complements previous imaging research showing that emotional and physical
pain both activate the same parts of the brain.
Researchers led by Adam T. Hirsh of the School of Science
at Indiana University - Purdue University Indianapolis report that black and white Americans cope with
pain differently and that blacks employ
pain coping strategies more frequently than whites.
The devices are being developed and studied by
researchers at Washington University School of Medicine in St. Louis and the University of Illinois
at Urbana - Champaign as a potential treatment for
pain that does not respond to other therapies.
German
researchers found osteopathic manipulative therapy (OMTh) decreased postpartum low back
pain by over 70 percent in women who had given birth
at least three months before beginning treatment, according to a new study published in July issue of the Journal of the American Osteopathic Association.
In a study in mice,
researchers at Duke Medicine identified a protein that is critical to TMJD
pain, and could be a promising target for developing treatments for the disorder.
In a report on the research, published in the December 27 issue of JAMA Dermatology, the
researchers call on physicians who treat women with central centrifugal cicatricial alopecia (CCCA) to make patients aware that they may be
at increased risk for fibroids and should be screened for the condition, particularly if they have symptoms such as heavy bleeding and
pain.
In a major breakthrough, a team led by
researchers at the Salk Institute and Harvard Medical School have identified an important neural mechanism in the spinal cord that appears to be capable of sending erroneous
pain signals to the brain.
In a study that appears in the May issue of the Journal of General Internal Medicine,
researchers at Boston University School of Medicine and Boston Medical Center have found that the majority of patients misusing drugs and alcohol have chronic
pain and many are using these substances to «self - medicate» their
pain.
«Without this kind of sensory input you can't be aware of your surroundings or
pain or be conscious,» says Hugo Lagercrantz, a neonatal
researcher at the Karolinska Institute in Stockholm, Sweden.
Patients who go to the emergency room (ER) with chest
pain often receive unnecessary tests to evaluate whether they are having a heart attack, a practice that provides no clinical benefit and adds hundreds of dollars in health - care costs, according to a new study from
researchers at Washington University School of Medicine in St. Louis.
In a controlled clinical trial,
researchers looked
at data from nearly 1,000 patients with chronic
pain who were treated with opioid
pain medication in four primary care practices.
Researchers at Washington State University in Spokane have identified a potential new approach to combating the joint
pain, inflammation and tissue damage caused by rheumatoid arthritis.
Two Phase III trials, conducted in Europe and in the United States by
researchers at the Icahn School of Medicine
at Mount Sinai and six other U.S. sites, showed that the duration of
pain - free time in the sun and quality of life were significantly improved by treatment with afamelanotide, a novel synthetic version of a melanocyte - stimulating hormone.
Eighteen months ago,
researchers at the Laboratory of Organic Electronics demonstrated an ion pump which
researchers at the Karolinska Institutet could use to reduce the sensation of
pain in awake, freely - moving rats.
The next step will be to test it with live cells and the
researchers hope eventually to, for example alleviate
pain, stop epileptic seizures, and reduce the symptoms of Parkinsons disease, using exactly the required dose
at exactly the affected cells.
Dr. Peltzer - Jones and her team of
researchers sought to examine the level of addiction of 255 super-frequent users who sought care
at Henry Ford's Emergency Department from 2004 - 2013 and determine whether imposing prescribing guidelines for narcotics in their ED impacted the level of patients seeking
pain - relief narcotics.
The
researchers identified which women took paracetamol, aspirin or ibuprofen for
pain relief during pregnancy, and investigated whether this raised the likelihood that their sons would have undescended testicles
at birth, a condition called cryptorchidism.
In three separate large analyses published between 2015 and this year,
researchers at the University of Sydney and their colleagues compared evidence from dozens of studies to determine how well various pharmaceutical options assuage back
pain and found all the drugs lacking.
Earlier studies demonstrated that mindfulness - based therapy could ease chronic
pain, so
researchers at the University of Canberra and elsewhere in Australia investigated whether a brief version of this approach would help people with chronic tension — type headaches (the most common kind).
A new study by a University of Texas
at Arlington physics team in collaboration with bioengineering and psychology
researchers shows for the first time how a small area of the brain can be optically stimulated to control
pain.
A team of
researchers around PD Dr. Hubert Dinse of the NeuralPlasticity Lab
at the Institute for Neuroinformatics, Prof. Dr. Martin Tegenthoff, Director of the Neurological Clinic, and Prof. Dr. Christoph Maier, senior physician of the Department for
Pain Medicine, both
at the Bergmannsheil University Clinic, have now investigated the effectiveness of this approach in
pain patients.
Aalto University neuroscientists, in collaboration with
researchers at Helsinki University Hospital and Harvard Medical School, have found a novel connection between the size of the choroid plexus in the brain and complex regional
pain syndrome (CRPS).
The quest for better opioids got a much - needed jolt in 1999, when
researchers at Duke University showed that mice lacking a protein called beta - arrestin 2 got more
pain relief from morphine than normal mice did.
To address this need,
researchers at University of Utah Health devised a system that allowed zebrafish, a small tropical fish, to self - administer doses of hydrocodone, an opioid commonly prescribed to people for
pain.
In working with mice,
researcher Jeffrey Mogil,
at McGill University's
Pain Genetics Lab, has found that the response to
pain can vary tremendously by breed and by gender.
So far, DARPA has released two calls for grant applications, with
at least one more likely: The first, called SUBNETS (Systems - Based Neurotechnology for Emerging Therapies), asks
researchers to develop novel, wireless devices, such as deep brain stimulators, that can cure neurological disorders such as posttraumatic stress (PTS), major depression, and chronic
pain.
The rodents showed significantly fewer signs of
pain (an average of a 36 % lower score on the grimace scale) when a male
researcher was in the room than when a female
researcher — or no
researcher at all — was there.
Patients with chest
pain have similar rates of heart attacks and other major cardiac events within two years whether they were evaluated with a new type of CT scan or the traditional stress test, according to results presented today by Duke Medicine
researchers at a meeting of the American College of Cardiology.
Rats and mice in
pain make facial expressions similar to those in humans — so similar, in fact, that a few years ago
researchers developed rodent «grimace scales,» which help them assess an animal's level of
pain simply by looking
at its face.
Wouter Haak, Vice-President of Research Data Management Solutions
at Elsevier, said: «The findings presented in this report help us — as well as research leaders, university and government policy makers — better understand where
pain points lie when it comes to the sentiment around and the reality of data sharing practices among
researchers.
People who experienced knee
pain at night while in bed, while putting on socks, or while getting in or out of a car were more likely to report having symptoms of depression, noted the
researchers.