Sentences with phrase «paired zinc finger nucleases»

Addgene depositor Charles Gersbach used paired zinc finger nucleases to remove exon 51 in DMD patient myoblasts.

Not exact matches

Here we describe engineering a pair of zinc finger nucleases that, when introduced into human T cells, efficiently disrupt cxcr4 by cleavage and error - prone non-homologous DNA end - joining.
To circumvent this, a CCR5 specific zinc - finger nuclease pair (R5 - ZFNs) has been developed [23].
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