Addgene depositor Charles Gersbach used
paired zinc finger nucleases to remove exon 51 in DMD patient myoblasts.
Not exact matches
Here we describe engineering a
pair of
zinc finger nucleases that, when introduced into human T cells, efficiently disrupt cxcr4 by cleavage and error - prone non-homologous DNA end - joining.
To circumvent this, a CCR5 specific
zinc -
finger nuclease pair (R5 - ZFNs) has been developed [23].