Sentences with phrase «palbociclib inhibiting»
The proteasome is a novel downstream target for the anti ‐ cancer drug palbociclib inhibiting proliferation by reduced proteasomal association with its inhibitor EMC29.
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«While it was known that palbociclib stalls proliferation by inhibiting CDK4 / 6, inducing proteasomal activity may be an additional mechanism that ensures the completeness of the cell cycle arrest,» says Dr. Mikael Björklund, one of the lead authors of the study.