Sentences with phrase «palindromic sequence»
Synthetic oligodeoxynucleotides with the following three features: poly (G) sequences at the 3 ′ end; a central palindromic sequence; and CG dinucleotides within the palindrome.
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These repeating sequences have been dubbed CRISPR (or Crispr), for Clustered Regularly Interspaced Short Palindromic Repeats.
Looking for a mechanism, researchers found remnants of genes from past infections, sandwiched between odd, repeated bacterial DNA sequences — the «clustered regularly interspaced short palindromic repeats» that give CRISPR its name.
LoxP (locus of X (cross)- over in P1) sites are 34 - base - pair long recognition sequences consisting of two 13 - bp long palindromic repeats separated by an 8 - bp long asymmetric core spacer sequence.
«CRISPR» stands for «clustered regularly interspaced palindromic repeats,» first described in 1987 by Japanese researchers who found chunks of oddly repeating DNA sequences in the genome of E. coli.
HAR1 does not code for a protein but for a long RNA, a type of molecule that guides proteins or modulates their expression.5 We predicted that the HAR1 RNA could fold into a three - dimensional structure because its conserved sequence has palindromic regions that pair up to form a series of interconnected «stems» that look like ladders — think of an untwisted DNA double helix.
The students are employing that technology — which includes CRISPR (clustered regularly interspaced short palindromic repeats) systems, DNA microarrays, real - time polymerase chain reactions, RNA sequencing and western blotting — to study acute myeloid leukemia (AML), which affects both children and adults and comes with a high mortality rate for older patients.
Fitness -, virulence - associated genome regions, and CRISPR / CAS (clustered regularly interspaced short palindromic repeats / CRISPR associated sequence) arrays of these STEC O156: H25 and O182: H25 isolates were highly similar, and identical genomic integration sites for the stx converting bacteriophages and the core LEE, identical Shiga toxin converting bacteriophage genes for stx1a, identical complete LEE loci, and identical sets of chemotaxis and flagellar genes were identified.
SIRs comprise palindromic arm sequences separated by short spacer sequences that form the hairpin stem and loop respectively.