She received the Texas A&M University College of Veterinary Medicine Fisher Institute Medical Research Award, 2004, for her dissertation, titled: Transmission genetics
of pancreatic acinar atrophy in the German Shep Dog.
She has been funded by the Canine Health Foundation to study several genetic diseases,
including pancreatic acinar atrophy (EPI) and degenerative myelopathy in the German shepherd dog.
For example, in collaboration with Dr. Leigh Anne Clark's group at the Clemson University in South Carolina we have identified an association of a specific DLA class I allele
with pancreatic acinar atrophy in the German Shepherd Dog.
Exocrine pancreatic insufficiency, sometimes
called pancreatic acinar atrophy (PAA), pancreatic hypoplasia, malabsorbtion, or malassimilation, is a potentially life - threatening autoimmune disease which attacks the parts of the pancreas that produce digestive enzymes.
Dr. Tsai is currently sequencing dog leukocyte antigen class I and II loci and assigning alleles for a funded study to evaluate if certain alleles are associated
with pancreatic acinar atrophy (EPI)
Exocrine pancreatic insufficiency — sometimes
called pancreatic acinar atrophy (PAA), pancreatic hypoplasia, malabsorbtion, or malassimilation — is an autoimmune disease which attacks the parts of the pancreas that produce digestive enzymes.
The most common cause of digestive enzyme deficiency in dogs is
pancreatic acinar atrophy, where the pancreas simply becomes shriveled and useless.
Pancreatic acinar atrophy (PAA) is probably the most common cause of exocrine pancreatic insufficiency (EPI) in the dog.
A familial predisposition to
pancreatic acinar atrophy has been reported in German Shepherd Dogs, Collies and English Setters (Westermarck 1980; Boari et al 1994; Moeller et al 2002; Wiberg 2004).
In dogs, EPI is usually due to
pancreatic acinar atrophy (PAA).
In dogs, this condition is often attributed to
pancreatic acinar atrophy, wherein the enzyme - producing acinar cells are believed to be destroyed through an autoimmune process.»