Outside of manual monitoring and insulin injections,
pancreatic cell treatments are an option, albeit an expensive and time consuming one.
Not exact matches
During lab testing, the compound «markedly inhibited» the growth of three human
pancreatic cancer
cell lines five days after
treatment and induced the death of
pancreatic cancer
cells.
The team believes that whichever way BMP - 7 is used, it will be less risky than other
treatments for type 1 diabetes that are currently being investigated, such as those that create
pancreatic cells from stem
cells, or by introducing new genes into the body.
In particular, although radiation
treatment regimens for some other cancers have been found to unleash an anti-tumor response by the patient's own T -
cells, the team found no such effect in their
pancreatic cancer model.
A protein that helps bones mend also transforms
pancreatic cells into insulin powerhouses — providing hope for a
treatment for type 1 diabetes
Treatment is difficult because
pancreatic tumours are protected by an armour of connective tissue, blood vessels and immune
cells, known collectively as the stroma.
UCLA scientists have unlocked an important mechanism that allows chemotherapy - carrying nanoparticles — extremely small objects between 1 and 100 nanometers (a billionth of a meter)-- to directly access
pancreatic cancer tumors, thereby improving the ability to kill cancer
cells and hence leading to more effective
treatment outcome of the disease.
Meng and Nel also collaborated with Dr. Timothy Donahue, chief of gastrointestinal and
pancreatic surgery and a Jonsson Comprehensive Cancer Center member, to demonstrate that
treatment with the iRGD peptide can enhance tumor
cell killing for patient - derived
pancreatic cancers, growing subcutaneously in a mouse model.
The analysis indicated that 48 hours of chokeberry extract
treatment of
pancreatic cancer
cells induced
cell death at 1 ug / ml.
One is a relatively unknown company, CyThera, set up less than 2 years ago in San Diego, that claims to have nine embryonic stem
cell lines and is currently trying to develop
pancreatic islet
cells for
treatment of diabetes.
All six mice with
pancreatic cancer were still alive at the end of the experiment, 113 days after
treatment with 5E5 CAR T
cells.
In the original agreement, WARF gave Geron exclusive rights to develop diagnostic and
treatment products in six types of stem
cell - derived
cell lines:
pancreatic, heart muscle, nerve, blood, bone, and liver.
Dr. Kulkarni's research focuses on investigating signaling pathways impacting growth and function of
pancreatic islet
cells with the long - term goal of improving therapeutic approaches for the
treatment of type 1 and type 2 diabetes and obesity - associated conditions.
Now, patients with
pancreatic cancer desperate for new
treatment options will potentially benefit from a powerful new technology that uses genetic engineering to turn their own immune
cells into «specially trained assassins» capable of finding, attacking, and eliminating
pancreatic cancer tumors.
Jan. 17, 2013 — Vanderbilt and University of California investigators have discovered the «
cell of origin» for
pancreatic ductal adenocarcinoma, a finding that could lead to early detection methods and new
treatments.
This suggests that
treatment with IL - 15 can successfully relieve tumor - resident killer T
cells from functional suppression and reactivate them to kill
pancreatic cancer
cells.
This Research Team is studying CAR T
cell immunotherapy in metastatic
pancreatic cancer patients, looking for changes in DNA «on and off switches» (epigenetic changes) following
treatment with CAR T.
1) The discovery that
pancreatic beta
cells, which produce insulin, have the ability to be regenerated from stem
cells or ductal
cells in the pancreas, indicating that one potential
treatment for type 1 diabetes is to stimulate beta
cells to regrow even after many years of living with diabetes
The researchers are reporting preclinical findings for a potential two -
treatment strategy to block multiple mechanisms of cancer
cell metabolism in
pancreatic cancer at the American Association for Cancer Research Annual...
We are recruiting people who have developed Type 1 Diabetes in the last 6 months to receive
treatments which aim to reset the immune system and mobilize stem
cells - hoping that will reverse or prevent further immune attack of
pancreatic beta
cells.
This research will have a significant impact on understanding neoantigen - T
cell immunobiology and could improve the
treatment prospects of
pancreatic cancer patients.
Specific targeting of the NLRP3 inflammasome to prevent
pancreatic β
cell death could allow for selective T2D
treatment without compromising all IL - 1β - associated immune responses.
Treatment of Type 1 Diabetes With Adipose Tissue — Derived Stem
Cells Expressing
Pancreatic Duodenal Homeobox 1 (December 2009) in Stem
Cells and Development.
This experimental
treatment for type 1 diabetes combines the Encaptra ™ drug delivery system, which is a semi-permeable pouch, and PEC - 01 ™
cells,
pancreatic precursor
cells derived from human embryonic stem
cells.
Another recent grant, awarded to Sandra Gollnick, PhD, Director of the Photodynamic Therapy Center, Member of the Department of
Cell Stress Biology and Distinguished Professor in the Department of Immunology, will enable the creation of an international registry compiling information about patients» responses to photodynamic therapy (PDT), an approach developed at Roswell Park that is now used in the
treatment of many lung, esophageal, head and neck,
pancreatic, and mesothelioma tumors.
The increased metabolism of
pancreatic islets dispersed
cells, after IF
treatment, indorses the higher insulin secretion.
Surgery not only helps in eliminating the cancerous
cells, but is also one of most important tools used to diagnose many cancers prior to
treatment, like laporatomy in case of dog
pancreatic cancer.
The
pancreatic cells are rested and then start functioning fully again, and this is also the reason some cats stop being diabetic or at least stop needing insulin or any specific diabetes
treatment.
Caplan ER, Peterson ME, Mullen HS, Quesenberry KE, Rosenthal KL, Hoeffer HL, Moroff SD: Diagnosis and
treatment of insulin - secreting
pancreatic islet
cell tumors in ferrets: 57 cases (1986 - 1994).
Current research focus is the
treatment of diabetes with an implantable, retrievable biocompatible device containing
pancreatic islet
cells.