Sentences with phrase «pancreatic islet function»

The far more nuanced and precise data produced by single cell analyses will allow for better understanding of pancreatic islet function and dysfunction at the cellular level.

Not exact matches

Dr. Kulkarni's research focuses on investigating signaling pathways impacting growth and function of pancreatic islet cells with the long - term goal of improving therapeutic approaches for the treatment of type 1 and type 2 diabetes and obesity - associated conditions.

This has been evidenced by 1) increased acinar cell necrosis, 2) increased serum amylase and lipase, 3) higher hepatic damage, 4) altered liver function test, 5) increased kidney damage, 6) increase in serum urea and creatinine, 7) altered distribution of pancreatic cells, 8) increased vacoulation and irregular islets, and 9) mild fibrosis in exocrine regions.

ViaCyte is developing a drug delivery system that enables implanted pancreatic progenitor cells to survive and differentiate into functioning insulin - producing islet cells.

Type 1 diabetes usually occurs early in life and affects more than one million Americans who are unable to manufacture their own insulin because their pancreatic islets do not function.

Type 1 Diabetes mellitus (T1D) is an autoimmune disorder characterized by a loss of function of insulin producing beta cells in pancreatic islets of langerhans leading to insulin insufficiency.

Vanderbilt University, «Improving isolation of pancreatic islets in T1D to assess alpha cell function and gene expression,» led by Drs. Al Powers and David Harlan (University of Massachusetts Medical School)