Sentences with phrase «pancreatic tumor samples»
Bottom Line: Bacterial load was significantly higher in pancreatic tumor samples from patients with pancreatic ductal adenocarcinoma compared with pancreatic tissue from normal individuals, and in studies using mice, eliminating certain «bad» bacteria slowed the growth of pancreatic cancer, reversed immune suppression, and upregulated the immune checkpoint protein PD1.
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The team is now working to create a repository of pancreatic tumor samples, coordinating with the National Cancer Institute.
Not exact matches
To better understand the formation of metastases in pancreatic cancer, Christine Iacobuzio - Donahue, M.D., Ph.D., professor of pathology at Memorial Sloan Kettering Cancer Center, collected tumor samples from eight patients with the most common form of pancreatic cancer (pancreatic ductal adenocarcinoma) immediately after their deaths.
A multicenter team of researchers reports that a full genomic analysis of tumor samples from a small number of people who died of pancreatic cancer suggests that chemical changes to DNA that do not affect the DNA sequence itself yet control how it operates confer survival advantages on subsets of pancreatic cancer cells.
In this study, samples were taken from patients» tumors during surgery and transplanted into mice to grow new pancreatic cancer tumors.
Guided by a camera and the ultrasound probe, Waxman carefully positioned the endoscope over the tumor and passed a fine needle into the pancreatic lesion to sample tissue cells for biopsy.
The researchers looked exclusively at small segments of DNA called promoters in samples of tumors taken from 308 pancreatic cancer patients.
In the first set of experiments, the Johns Hopkins scientists sequenced nearly all protein - encoding genes in 10 of the 68 samples of pancreatic neuroendocrine tumors and compared these sequences with normal DNA from each patient to identify tumor - specific changes or mutations.