The variant has been found in two men with prostate cancer, and in vitro analysis suggests it causes
a partial loss of function of the gene.
In the case of CHD2, scientists collaborating with the EuroEPINOMICS RES consortium used antisense technology to rapidly generate zebrafish larvae with
a partial loss of function of this gene, and were then able to detect epileptic seizures in these animals using electrographic analysis (this method is very similar to electroencephalography, or EEG, which is used to analyze seizures in humans).
Not exact matches
Because
partial nephrectomy provides superior oncologic control — sometimes at the expense
of renal
function loss and increased overall mortality — analysis
of how these factors should be weighed may facilitate clearer guidelines for selection among nephron - sparing treatments.
In most cases
of familial motor neuronopathy, the disease is caused by either gain -
of - adverse - effect mutations or
partial loss -
of -
function mutations in ubiquitously expressed genes that serve essential cellular
functions.
However, it can also arise where a common, externally forced growth signal influences the more localized fit
of a standardization curve, resulting in the
partial, or even complete,
loss of a relatively short - term climate signal (in the case
of more flexible standardization curves) and the distortion
of medium - term climate trends in adjacent periods (where less flexible, but still «fitted,» standardization
functions are employed).
If you've lost full or
partial function in a limb or body part, or suffered a work - related amputation, you would be eligible for benefits under «schedule
loss of use».
Either form
of paralysis can be complete (total
loss of function and sensation below the injury) or
partial.
Massachusetts workers can receive workers» compensation benefits for any disfigurement (s) and / or
loss of function of a body part that occur as a result
of an injury while at work — such as permanent scarring on the face, neck or arms — and are also entitled to benefits if an injury caused
partial or permanent
loss of function to any part
of their body, such as their arms or legs.
A spinal cord injury often results in a
loss, either
partial or complete,
of sensation, strength or
function, below where the injury occurred.
Spinal cord injuries refer to any damage to the spinal cord that results in
loss of motor
function, sensation or
partial or total paralysis.
Permanent
partial disability: a severe injury that is permanent, such as the
loss of sight in one eye, but where the worker will be able to resume some job
functions.