They used mass spectrometry to analyse the blood plasma of 53
participants with mild cognitive impairment or Alzheimer's disease, including 18 who developed symptoms during the study, and 53 who remained cognitively healthy.
A study of 60
participants with mild depression has shown that treatment with 3 g of Carnitine daily for two months significantly reduced symptoms as compared to placebo.
Five
participants with mild to moderate Alzheimer's disease took benfotiamine (300 mg daily) for 18 months.
In one six - week study,
participants with mild - to - moderate hypertension took 75 mg of extract twice a day.
In one of these studies, 9 elderly
participants with mild cognitive impairment consumed blueberry juice every day.
Participants with Mild Alzheimer's Disease will be given either Solanezumab every 4 weeks for 18 months, or a Placebo every 4 weeks for 18 months.
Wilkinson said he was surprised that on every test, participants who had mild TBI and hypopituitarism had more problems than did
participants with mild TBI but no hypopituitarism and those with no blast exposure.
Conversely, those with negative scans experienced much less decline: 90 percent of
participants with mild cognitive impairment but no plaque did not progress to Alzheimer's.
A small 2009 study found that of the 41
participants with mild cognitive impairment, those who had higher stress ratings also had faster rates of cognitive decline.
Not exact matches
In their experiment,
participants were repeatedly shown a blue square while receiving
mild electric shocks on the wrist, and learned to associate the two stimuli, so that afterwards they responded to the square
with fear.
People
with mild cognitive impairment were defined as those who have a slight decline in cognition, mainly in memory in terms of remembering sequences or organization, and who score lower on tests such as the California Verbal Learning Test, which requires
participants to recall a list of related words, such as a shopping list.
In the California Verbal Learning Test, on a scale of 0 to 80,
with 80 reflecting the best memory, the healthy
participants had an average score of 55.8, whereas those
with mild cognitive impairment scored an average of 40.5.
Also, the study
participants had
milder strokes on average than people
with stroke overall and the average age of
participants was 62, which is lower than the average age of 69 for people
with stroke overall.
In a large population - based study of randomly selected
participants in Germany, researchers found that
mild cognitive impairment (MCI) occurred significantly more often in individuals diagnosed
with a lower ankle brachial index (ABI), which is a marker of generalized atherosclerosis and thus cumulative exposure to cardiovascular risk factors during lifetime.
For example, a
participant with schizophrenia may have
mild depressive symptoms that are not accounted for in the treatment plan.
As expected, the researchers found that the group of
participants who had high levels of anti-HA antibodies when enrolled in the trial experienced a significantly lower incidence of
mild - to - moderate influenza disease and some reduction in its duration compared
with participants with low HA antibody levels.
Three groups of
participants were used in the study: people
with mild - to - moderate hearing loss and
mild tinnitus; people
with mild - to - moderate hearing loss without tinnitus; and a control group of age - matched people without hearing loss or tinnitus.
The study found that more than half the
participants had OSA, including 36.5 percent
with mild OSA and 16.8 percent
with moderate to severe OSA.
The research team found a 24 percent increase in the risk of developing cancer among
participants with severe periodontitis, compared to those
with mild to no periodontitis at baseline.
An 80 percent increase in risk of colon cancer observed for
participants who were edentulous at baseline, which is consistent
with prior findings, and among never smokers, a two-fold higher risk was noted for
participants with severe periodontitis, compared to those who had no /
mild periodontitis.
Half of the study
participants had been diagnosed
with either a
mild, moderate or severe traumatic brain injury and half had not.
When the researchers did sub-group analyses, they found that
participants with severe periodontal disease had more than double the risk of developing lung cancer, compared
with no /
mild periodontitis.
By testing cycling time to task failure (TTF) in a group of 12 active
participants in a placebo controlled study, Dr Mauger discovered that stimulating the brain by passing a
mild electrical current (transcranial direct current stimulation or tDCS) over the scalp to stimulate it increased the activity of the area associated
with muscle contraction.
Compared to the neurologists» diagnoses, the device displayed 92 percent specificity — the ability to detect the difference between patients
with severe stroke and those
with other conditions such as
mild stroke or healthy
participants with no brain pathology.
Thirty - five percent of plaque - positive
participants who started
with mild cognitive impairment progressed to Alzheimer's, compared to 10 percent without plaque.
Of the
participants, 69 had normal cognitive function at the start of the study, 52 had been recently diagnosed
with mild cognitive impairment, and 31 were diagnosed
with Alzheimer's disease.
Each
participant received either a single shot of an experimental vaccine or a placebo and were then infected
with a
mild form of the virus six months later.
Methods: We performed a cross-sectional study in which 97 healthy
participants, 34
with aMCI, and 33
with mild AD were studied
with LASSI - L and a comprehensive neuropsychological protocol.
Further research published in the journal Neuropsychology studied the effects of being bilingual on the executive functioning of two groups of
participants: 75 people
with a diagnosis of Alzheimer's disease and 74
with a diagnosis of
mild cognitive impairment, a condition that sometimes progresses into Alzheimer's disease.
Forty - six
participants were enrolled; 27
with isolated
mild TBI and 19 controls who had nonsurgical extremity injuries and no head trauma.
Participants were divided into four groups: those diagnosed
with probable Alzheimer's when entering the study, healthy controls
with no sign of dementia, individuals
with mild cognitive impairment that remained stable over the two to three years for which scans were available, and those
with mild cognitive impairment that progressed to Alzheimer's disease during the study.
After four years of follow - up evaluations, 200
participants were beginning to show
mild cognitive impairment, problems
with memory, language, thinking and judgment that are greater than normal age - related changes.
In one study, detailed in the Sept. 12 issue of the journal Neurology, researchers compared the brain scans of 120 people belonging to three groups: 40 of the
participants had
mild cognitive impairment (MCI), a transition stage between normal aging and the more serious memory problems associated
with Alzheimer's disease; 40 complained of significant memory problems but did not have MCI and 40 were healthy controls.
Comparisons of symptoms from the beginning to the end of the 8 - week study showed considerable improvement in RLS - related symptom severity
with all but 1
participant rating her symptoms in the minimal to
mild range.
The
participants selected had to have similar physical ability, assessed
with the activities of daily living (ADL) score, and normal cognitive function or only
mild cognitive disturbance as defined by a Mini-Mental State Examination > 20 (18).
In addition, the 25 percent of the
participants who had
mild cognitive impairment associated
with Alzheimer's also experienced an increase in brain volume due to the higher amounts of exercise.
The researchers found that the study
participants who were involved
with social, craft, computer, or artistic activities had a reduced risk for developing
mild cognitive impairment (MCI).
Many other long - distance skating races and events on lakes and canals
with between one and two million
participants across the country did take place last week and several are still scheduled for Monday — when the thaw is forecast to set in, as cold air from Arctic Russia is pushed aside by wet and
mild air from Iceland.
Participants aged between 18 and 65 years, familiar
with the use of personal computers and suffering from
mild to moderate levels of major depression and / or dysthymia and / or
mild to moderate comorbid anxiety were eligible for the study.
The criteria for inclusion will be
participants who have HF NYHA class two (
Mild), three (Moderate) and four (Severe),
with depression or depressive symptoms.
Participants were adult heterosexual couples who were the caregivers of, and living
with, a child between the ages of 2 and 18 years diagnosed
with one of six chronic medical conditions: asthma (at least
mild persistent in severity), cystic fibrosis, type 1 diabetes mellitus, phenylketonuria (PKU), inflammatory bowel disease, or spina bifida.