However, the GVPs analyzed in this study originate from one position on the genome and genetic databases allow for accurate estimation of the distribution of
a particular SNP in a sample population.
«The standard example is that
a particular SNP is closely linked to being lactose intolerant,» Simmons explains.
In one, the user asks for the statistical correlation between
a particular SNP and a particular disease.
Each person carries about three million SNPs, but if
a particular SNP occurs more frequently in people with a particular condition than in people without the condition, it can pinpoint the underlying reason for the difference.
Yet
the particular SNP variants documented in these reports would place both women's male fetuses, and their alleged fathers, onto three branches of the tree simultaneously (see one example).
However, we did detect associations of
particular SNPs with certain symptoms and / or their severity.
Not exact matches
She now talks about Alex Salmond, the former leader of the
SNP of course, who also lost his seat: «I want to make
particular mention of Alex Salmond, my friend and mentor for almost 30 years and without a shadow of a doubt the giant of modern Scottish politics.»
YouGov have no way of knowing if any
particular Scottish poll, their sample is biased towards Labour die - hards, or towards those who vote Labour at UK level, but
SNP for Holyrood.
Researchers use the Immunochip to investigate DNA samples from people with a
particular disease for linkage disequilibrium (LD) signals that illuminate associations between specific
SNPs and the disease.
In the other, the user asks for a list of the
SNPs in a
particular region of the genome that correlate best with a
particular disease.
In
particular, one of the platforms used in their work, the Illumina 610 - Quad array, has been shown in unpublished studies by other investigators to produce artifactual genotype data at a subset of
SNPs.
Unlike the
SNP - based analysis described above, single - sample genotype calling was performed with no
particular ascertainment scheme, and we restricted our analysis to eight canid genomes with coverage ranging from 8 to 24 ×.
We also observed no increased susceptibility to ME / CFS among individuals carrying
particular haplogroups or
SNPs within a haplogroup.
Using a cohort of 193 ME / CFS cases and 196 controls, at 5 % FDR we observed eight mtDNA
SNPs to be associated with 16 symptom categories and three haplogroups associated with six symptom categories, suggesting that the mitochondrial genome of an individual with ME / CFS can affect the type and severity of
particular symptoms.
No increase in susceptibility to ME / CFS of individuals carrying
particular mitochondrial genomes or
SNPs was observed.
We carried out association testing to find whether any
SNPs were significantly associated with ME / CFS status or with
particular symptoms and their severity in the patient cohort.
Identifying
SNPs associated with
particular diseases will enable scientists to predict an individual's likelihood of developing a disease and how the disease runs in families.