Sentences with phrase «particular cell types»

Recent theorizing within this tradition suggests that these shifts may be manifested in changes in the relative frequency of particular cell types in blood (Irwin and Cole, 2011) as well as in the epigenetic programming and gene expression of such cells (Miller et al., 2011a).

In each case there is interest in obtaining comprehensive, accurate data for particular cell types and in identifying patterns of variation within the data.

«There is a lot of excitement in stem cell biology these days about the possibility of rationally and efficiently generating particular cell types from different stem cells for therapeutic purposes,» he said.

However, it is difficult to conclude from mixed tissue samples which genes are expressed by particular cell types.

We know exactly which cell types are affected, and so we really need to figure out ways to monitor and treat those particular cell types.

Early in cerebellar development, particular cell types come to be distributed unevenly from top to bottom, creating a dorsal - ventral separation.

Previous studies have demonstrated that particular cell types, such as those that constitute the retina or cornea, can be created in the laboratory from pluripotent stem cells.

While the genetic code carried in our DNA provides instructions for cells to manufacture specific proteins, it is a second code that determines which genes are in fact activated in particular cell types.

«Targeting something that is fundamental and not just a peculiarity of a particular cell type holds greater promise.»

For example, one thing that we are doing is to try to differentiate individual pluripotent stem cells into a particular cell type with a shotgun approach.

These specialised processes involve proteins that are mainly expressed in this particular cell type throughout the body, which are often modulated in vascular disease.

Manuscripts typical of this section would describe experiments generating and analyzing lists of genes and studies of how those genes combine to regulate: differentiation of a particular cell type; cellular, tissue, or organ response to toxic / pathogenic agents; adaptation to environmental stresses.

By counting the number of enterocytes along the a / p axis, bands of GFP expression were approximately mapped to subregions (Figure 1F — G, dashed lines) in each particular cell type (Figure 1 — figure supplement 2).

Not exact matches

Recent insights into learning - oriented brain cells called mirror neurons even hold out the possibility that someday we will have pills that will impart particular types of skills, such as computer programming or business decision making.

The location - sharing practice does not appear to be limited to any particular type of Android phone or tablet; Google was apparently collecting cell tower data from all modern Android devices before being contacted by Quartz.

Embryonic cells are pluripotent, having the full genetic code enabling them to become any type of cell; they differentiate into particular cells in their later development.

«When someone has a problem — whether they need to find a particular cell line or need to understand the formulation of a particular type of culture medium — they're coming to you and they're in a crisis.

«The problem with plasma cell - free liquid biopsy in particular is that the amount of wild - type [DNA] can be very, very high, and so keeping that really rare signal from being swamped out by the wild - type... is key,» says Dawne Shelton, R&D manager for in vitro diagnostic products at Bio-Rad in Hercules, California.

«Each area of the brain is different with distinct cell types and connectivity, so if we can confirm that one area of circuitry is more involved in a particular symptom than another, we may eventually be able to treat a depression patient more efficiently than treating everyone the same way.»

The stem cells are a particular type, called hematopoietic stem cells, that make blood cells.

«We hope that these new insights will make it possible to modulate the differentiation of stem cells — causing them to generate cells of a particular type,» says Carell.

In the presence of Acinetobacter and Akkermansia, they became a particular type of T helper cell, which trigger inflammation and help the immune system kill off invaders or infected cells, the researchers report today in the Proceedings of the National Academy of Sciences (PNAS).

But getting pluripotent stem cells to differentiate into a particular type of cell that can function inside the body is not simple.

Among patients who have this type of lung cancer, nearly one in three will carry a particular genetic mutation on their cancer cells.

«A personalised immunotherapy was prepared for each patient by taking a sample of their blood and extracting a particular type of immune cell called dendritic cells.

The T - lymphocytes, or T - cells, are a particular type of white blood corpuscle that is important to the immune system.

The volunteers, ranging in age from 20 to 88, received injections under their retina of a particular type of eye cell, retinal pigment epithelium (RPE) cells, which were derived from hESCs in the lab.

Scientists are hopeful that ultimately these cells could be transformed in the laboratory to yield specific cell types needed for a particular treatment, or to cross the «blood - brain barrier» by expressing specific therapeutic agents that are released directly into the brain.

A team led by professor Massimiliano Mazzone has demonstrated that the metabolism of macrophages, a particular type of white blood cell, can be attuned to prevent the spread of cancer.

The company's goal is to create a comprehensive source of stem cells that could be of particular use for treating people of Middle Eastern descent, whose tissue types are often underrepresented in the public tissue banks such as those in the U.S. and elsewhere.

Living in overcrowded conditions appears to protect children and young adults against developing a particular type of Hodgkin lymphoma (HL), a cancer that originates from the lymphocytes (white blood cells).

New technologies are coming to the fore that allow interrogation of the types of cells interacting with tumors, in particular providing intelligence on the broad variety of complex associations between tumor cells and the immune system.

Five years ago, he got the idea to test whether a particular type of one - celled slime mold, Physarum polycephalum, could navigate through a maze.

Adult stem cells: They have less flexibility and «stemness» to change into different cell types, but they can still produce new cells, specialized to become part of a particular organ or tissue, such as muscle cells or neural cells.

While studying why some mice resist HSK, a team led by immunologist Harvey Cantor of Harvard Medical School in Boston found that possession of a particular variant of one type of antibody renders T cells incapable of attacking tissue in the cornea, the transparent covering of the iris and pupil.

Knocking out a particular gene in muscle lets mice run twice as far as normal; knocking out the same gene in fat cells allows the animals to put on weight without developing type - 2 diabetes.

Too much of one particular type of fat, or lipid, in a membrane shifts and turns K - Ras, shoving its active portion away from the membrane and into the cell, where it can transmit cancer - causing signals.

Harvard School of Public Health (HSPH) researchers have discovered that a particular type of protein (hormone) found in fat cells helps regulate how glucose (blood sugar) is controlled and metabolized (used for energy) in the liver.

Dogs can do that because their noses contain 900 different types of olfactory receptors, chemical detectors in cells that respond to many different kinds of odor molecules in particular ways.

Cancer stem cells, a type of self - renewing cell found in tumors, are of particular interest because they are the main cell type responsible for tumor progression and for resistance to chemotherapy and radiotherapy, and therefore a major cause of tumor recurrence after treatment.

«Use of induced pluripotent stem cell (iPSC) technology» — which involves taking skin cells from patients and reprogramming them into embryonic - like stem cells capable of turning into other specific cell types relevant for studying a particular disease — «makes it possible to model dementias that affect people later in life,» says senior study author Catherine Verfaillie of KU Leuven.

Yet in other cases, a missing cell type is responsible for causing a particular disease.

Understanding how a particular DNA sequence gives rise to a particular protein provides us with some insight into that protein, but a deeper investigation of how the protein is made, where it is located, and how much of it is present in different cell types is required to enable a true understanding of its function.

Narrowing the treatment to a particular tumor cell type makes for a more effective — and less harmful — oncolytic approach.

In lymph nodes, a particular type of stromal cells that forms a scaffold for lymphocytes to crawl around within the node normally secretes an enzyme called autotaxin, which is responsible for the production of the lipid signaling molecule, lysophosphatidic acid (LPA).

Agata Smogorzewska, head of the Laboratory of Genome Maintenance, wants to understand how cells repair interstrand cross-links, a particular type of DNA damage in which the two strands of the double helix that normally twine about each other become physically linked.

Different GPCRs showed up on different neurons, allowing the scientists to parse specific cell types that might direct particular vagus nerve functions.

This research reveals a new type of cell fusion that is initiated to destroy a particular cell, and enlightens the evolution of sexual reproduction in flowering plants.

This particular type of cell - based HTS assay is used by many of the fast - track biotechs and pharmaceutical companies, and they take good care of their people.

It's a mystery,» he said, suggesting that it could mean stem cells thought to be committed to a particular lineage may be capable of becoming other types of tissue entirely.