Sentences with phrase «particular genes in the genome»

Not exact matches

By combining each mouse's genome, phenome, proteome and metabolome, the scientists were able to identify a particular gene, located on their chromosome 2, and whose presence plays an important role in the development of type 2 diabetes «The mice with a high - fat diet are more or less likely to develop diabetes depending on whether this gene is active or not,» said Evan Williams, LISP PhD student and the article's co-first author.

In particular, genes account for only 1.2 percent of the genome's three billion bases.

Currently, you can cheaply search for one particular gene or disease in great detail or you can search your whole genome in poor detail.

While several studies in the intervening years have investigated whether particular genes were responsible for modifying HD onset, this is the first to employ genome - wide association (GWA) analysis, which scans an individual's whole genome to identify chromosomal regions containing variants that are associated with the disease traits that are being studied.

Moore has used landmarks on the rice genome to help wheat researchers like himself to home in on particular genes they are interested in, an approach that can be extended to the other cereals, too.

To figure out what's really happening within an organism — or within a particular organ or cell — researchers are linking the genome with large - scale data about the output of those genes at specific times, in specific places, in response to specific environmental pressures.

But geneticists have been struggling to find ways of directing beneficial genes to particular spots in the genome.

Over the longer term, the identification of the coffee tree genome sequence opens up new possibilities for varietal improvement, knowledge of the specific functions of the genes (in particular those specific to coffee trees), the possibility of transferring results to other species, and refining diagnostic tools for the function of the plant.

And although the rest of Genghis Khan's genome has certainly, if Zerjal and Tyler - Smith are right, made an outsize contribution to the Central Asian gene pool, it has been chopped to bits and mixed in so thoroughly over the centuries by genetic recombination that no one today is likely to have his whole suite of genes for any particular trait.

As more such species are sequenced, he says, «everyone will be using these» genomes to find out which genes are responsible for particular functions, especially for plant pathogens such as Fusarium, which causes ear rot in corn and puts out mycotoxins in animal feed.

In particular, the Neandertal genome sequence can now be used to catalog changes that have become «fixed» (are invariant within a population or species) in modern humans during the last few hundred thousand years and should be helpful for identifying genes affected by positive selection since humans diverged from NeandertalIn particular, the Neandertal genome sequence can now be used to catalog changes that have become «fixed» (are invariant within a population or species) in modern humans during the last few hundred thousand years and should be helpful for identifying genes affected by positive selection since humans diverged from Neandertalin modern humans during the last few hundred thousand years and should be helpful for identifying genes affected by positive selection since humans diverged from Neandertals.

How these self - promoting genes jump to these prime locations remains a mystery, but the researchers believe it may have to do with the DNA's three - dimensional structure in particular areas that allows for genetic rearrangement when the genome is being copied or when certain genes are active.

In particular, genes, rather than non-genic regions of the genome, appeared to be preferentially protected from mutation in the MMR - proficient straiIn particular, genes, rather than non-genic regions of the genome, appeared to be preferentially protected from mutation in the MMR - proficient straiin the MMR - proficient strain.

Assembly of the Norway spruce genome has shown that LTR retrotransposons in particular are frequently nested within the long introns of some gene families (Nystedt et al. 2013).

From this we compared the genomic distributions of our hotspots to the genomic distribution of various features associated with genome evolution and genes that participate in particular biological processes.

Broadly speaking, we are interested in understanding how genes affect behaviour, but despite rapid advances in technology for sequencing and engineering genomes, it is still a challenge to associate particular genes with heritable behavioural differences because behaviour is time consuming to measure and difficult to quantify.

Henk Stunnenberg, leader of one of the research groups that carried out the study and coordinator of both Heroic and the recently started High Impact Project BLUEPRINT, said: «The epigenetic make - up - a layer of regulatory instructions on top of the genome - of the pure embryonic stem cells shows remarkable and unexpected features, in particular with respect to developmental genes.

The scientists had strategically inserted these foreign DNA «markers» at particular points along the genome, next to genes expressed only in embryonic stem cells.

Okano's group has also succeeded in using a state - of - the - art technique called genome editing in marmosets, which could be used to generate «knock - out» monkeys, in which specific genes are deleted or inactivated in specified brain regions, and at a particular stage of brain development.

Since the completion of the canine genome in 2005, science has been able to pinpoint individual genes responsible for particular traits.

Diet - related nutrogenic diseases can be aggravated when various food ingredients alter the health - promoting population of bacteria in the digestive system, the «microbiome» or «garden of the guts,» and when a particular breed or individual genome has gene - related processes and reactions to food ingredients that cause or aggravate illness.