In the current study, which was conducted in mice, scientists have analyzed one
particular single nucleotide variant in a region associated with increased risk for developing colorectal and prostate cancers, but whose mechanism of action has been unclear.
In a study, published in Science, they investigated a gene region that contains
a particular single nucleotide variant associated with increased risk for developing colorectal and prostate cancers — and found that removing this region caused dramatic resistance to tumor formation.
Not exact matches
The research team's hunt for such age - related genetic associations involved studying more than 8 million
single nucleotide polymorphisms — changes of one
nucleotide for another at a
particular spot in the DNA — in 2,693 individuals.
Furthermore, the analysis of data on
single -
nucleotide polymorphisms, the main cause of difference between human beings, allows the prediction of phenotypic effects of a
particular genetic variation.