Sentences with phrase «particularly high importance»

This issue is of particularly high importance since it might support the causality of this association.

Not exact matches

Project days are a time to work on high - importance, low - urgency projects, particularly those requiring focus and creativity: drafting a manuscript, planning a project, interpreting a new dataset.

«Freedom of religion is widely embraced around the world, but it is particularly significant to people who place high importance on religion in their lives,» stated Pew.

While talking to the high school team, Gonzalez stressed the importance of nutrition and rest as a baseball player, particularly a developing one.

«This finding emphasizes the importance of adequate food availability in controlling TB incidence, particularly in areas with high HIV prevalence,» said Silverman.

What counts is the impact on the reduction of vaccine - preventable disease incidence through direct and indirect protection, which is particularly pertinent for diseases that are of high public health importance.

To understand the selection mechanism behind mutations, network - based studies were used to estimate the importance of a mutated protein compared to non-mutated ones in signalling and protein — protein interaction networks.10, 11,12,13 Proteins mutated in cancer were found having a high number of interacting partners (i.e., a high degree of connectivity), which indicates high local importance.10 Mutated proteins are also often found in the centre of the network, in key global positions, as quantified by the number of shortest paths passing through them if all proteins are connected with each other (i.e., they have high betweenness centrality; hereafter called betweenness).11, 12 Mutated proteins also have high clustering coefficients, which means their neighbours are also neighbours of each other.10, 13 Moreover, neighbourhood analysis of mutated proteins have been previously successfully used to predict novel cancer - related genes.14, 15 However, to the best of our knowledge, no study has concentrated particularly on the topological importance of first neighbours of mutated proteins in cancer, and their usefulness as drug targets themselves.

Indeed, unlike animal protein, plant protein has not been associated with increased insulinlike growth factor 1 levels28, 29 and has been linked to lower blood pressure,30 - 32 reduced low - density lipoprotein levels,32 - 34 and improved insulin sensitivity.35 Substitution of plant protein for animal protein has been related to a lower incidence of CVD36 - 39 and type 2 diabetes.40 - 42 Moreover, although a high intake of red meat, particularly processed red meat, has been associated with increased mortality in a recent meta - analysis of 13 cohort studies, 43 high consumption of nuts, a major contributor to plant protein, has been associated lower CVD and all - cause mortality.44 These results underscore the importance of protein sources for risk assessment and suggest that other components in protein - rich foods (eg, sodium, 45 nitrates, and nitrites46 in processed red meat), in addition to protein per se, may have a critical health effect.

Woven into this highly personal narrative about a boy's journey from silent sidekick to hero are themes that translate to public education: the challenges of finding the right school or instructional method to meet a student's individual needs; the impact of social stigmas on expectations and performance, particularly for «discarded students» in low - income neighborhoods, and the need for a culture of high expectations to counter those negative societal assumptions; the importance of tireless, focused, caring teachers who do whatever it takes to help students succeed; and the ability for all children — regardless of learning challenges or race or income level — to learn.

Teacher quality and development are of the utmost importance to all schools, but particularly those in low - income neighborhoods with high minority and English - Learning populations.

In the EP Blog post «Four Places to Support Equity and Boost Your Career Like Nowhere Else,» we discussed the importance of the network's «accelerator cities» — some of our smaller locations that are high priority because they have a particularly high demand for talented leaders, as well as offer unique opportunities to impact education and advance careers rapidly.

Mr. Toscano emphasizes the importance of providing a high - quality curriculum to «all» students, particularly the underserved.

Many advocates are focused on raising awareness of the importance of early learning, while also calling for increased funding to expand access and ensure high quality, particularly for underserved communities.

The speed capability of motor vehicles climbed quickly in the embryonic industry as illustrated by the top speeds of some typical production cars... With higher speeds the dynamics of the vehicles, particularly turning and braking, issued greater importance as an engineering concern.

Given the «growing importance of high - growth stocks to the UK stockmarket, particularly those in technology - related areas», they concluded that the fund was «too heavily biased towards stocks in out - of - favour, lowly rated companies known as value stocks».

It seems to me that science, particularly climate science, has some very serious issues that high light a narcissistic self importance in that a lot of modern scientists, particularly in climate science, now seem to believe they have a role in and a god given right to try and ensure the implementation of their own personally believed ideologies.

Wramneby et al (2010) explored the regional interaction between climate and vegetation response using a RCM set - up, and highlighted the importance of this interaction for assessing the mean temperature response particularly at high latitudes (due to the role of vegetation in snow covered areas) and in water limited evaporation regimes (due to the role of vegetation in controlling surface evaporative cooling).

Coal, by far the most polluting of the fossil fuels, is also of increasing importance — particularly in Asia where the highest energy demand increases are predicted.

However, while these concerns could be of great importance to any lawyer, junior or otherwise, an important consideration above all else is this: We have chosen to enter a profession that holds us to a high bar when it comes to ethical standards, choices and behaviour — a valuable consideration for in - house counsel, particularly when faced with internal pressures.

This job holds high importance as the reputation of the organization depends on how documents and specimens are handled, particularly where the integrity of samples is concerned.

Regarding the child, the importance of the intrauterine and early postnatal environments for metabolic programming and modifications of the epigenome is increasingly recognised, 12 — 14 particularly for metabolic diseases such as obesity and diabetes.15 Thus, GDM is related to macrosomia at birth (> 4 kg), to excess body fat and (central) obesity and to insulin secretion in infants and children, the obesity being in part mediated by maternal body mass index (BMI) or birth weight.16 — 23 Intrauterine exposure to GDM also doubles the risk for subsequent type 2 diabetes in offspring compared with offspring of mothers with a high genetic predisposition for type 2 diabetes, but with normal glucose tolerance during the index pregnancy.24 Maternal prepregnancy overweight and excessive gestational weight gain also predict high birth weight and adiposity during infancy.12 25 This is highly relevant, as up to 60 % — 70 % of women with GDM are overweight or obese before pregnancy.26 Finally, maternal lifestyle behaviour such as a high fat diet or lack of physical activity during pregnancy can influence offspring adiposity independent of maternal obesity.12 27

Research shows the importance of participation in activity programs in increasing high school graduation and later success in life, particularly for disadvantaged students.

Research shows it has the potential to promote normal developmental trajectories for high - risk children, such as those from low - income backgrounds and / or those with very premature births.13 In contrast, unresponsive parenting may jeopardize children's development, particularly those at higher risk for developmental problems.14 The critical importance of responsive parenting is highlighted by recent evidence identifying links between high levels of early responsive parenting and larger hippocampal volumes for normally developing preschool aged children.

Several reviews have noted the importance of understanding reasons for attrition, particularly in trials involving high - risk groups — teenage parents, those at risk of abuse, those who abuse drugs and alcohol and those who have been convicted of abuse.