Sentences with phrase «pathological alpha synuclein»
Not exact matches
Researchers at the University of Pittsburgh School of Medicine have uncovered a major reason why the Parkinson's - related protein alpha - synuclein, a major constituent of the Lewy bodies that are the pathological hallmark of Parkinson's disease (PD), is toxic to neurons in the brain.
https://www.sciencedaily.com/
The pathological hallmark of this disease is the accumulation of alpha - synuclein, which in turn leads to cell death and consequently to problems in neurotransmission.
Our results indicate however, that if pathological alpha - synuclein is detected outside the brain, this does not necessarily mark the site where the disease started.»
The main component of pathological protein fibrils in Parkinson's disease is alpha - synuclein.