Sentences with word «pathophysiology»

Pathophysiology refers to the study of how diseases or disorders affect the normal functioning of the body. It focuses on understanding the changes that occur in the body's functioning, such as the causes, mechanisms, and effects of these diseases or disorders. Full definition
Detection of early motor deficits, together with the genetic similarities to the human condition, would further support the use of heterozygous knock in mice as a tool for examining the early mechanisms of pathophysiology of HD and for screening potential treatments.
The potential role of hypocortisolism in pathophysiology of stress related bodily disorders
MGMGB investigators use the rich resources and technologies of the Human Genome Project to develop more sophisticated ways of understanding pathophysiology, diagnosis and treatment of disease.
Since the recent discovery of tremendous biological effects of nitric oxide, other small gaseous molecules such as carbon monoxide or hydrogen sulfide have emerged to be similarly important in cell signaling, with a great impact on pathophysiology of various diseases.
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This study was selected for the Trainee Paper Spotlight because it uses multiple techniques to understand disease pathophysiology from identification of genetic variants to evaluation of their role in disease pathogenesis.
To fully realize the field's clinical potential, the tissue engineers of the future must possess «a broad understanding of basic sciences (including biology, chemistry, and physics) and a sophisticated understanding of human pathophysiology, stem cell biology, and tissue mechanics.»
The molecular pathophysiology of neuropsychiatric disorders is still not well understood, and the development of new antipsychotic drugs is imperative.
There are over 40 human diseases with pathophysiology attributable to protein misfolding and misfolded protein aggregation.
Nutritional Symptomatolgy & Pathophysiology Section 2 of the Advanced Holistic Nutritionist Program Recognizing symptoms in relation to health issues is...
The research team members were Martinez - Trujillo; Sachs; Matthew Leavitt, a PhD student at the department of physiology at McGill University, Montreal; and Florian Pieper of the department of neuro - and pathophysiology at University Medical Centre Hamburg - Eppendorf in Germany.
Researchers showed that the changes imposed by different pathophysiology specifically affect the top of the functional hierarchy, at the level of chemical species.
This finding suggests that a common pathophysiology throughout the neural «language» loop that connects the frontal and posterior temporal lobe likely contributes to stuttering severity.
I've studied Bio-chem and pathophysiology as well as Radiology.
«The complex pathophysiology of schizophrenia and resultant patient heterogeneity present significant challenges to developing new and effective therapies for this disorder,» said corresponding author Dr. Bruce Kinon of Lundbeck LLC.
The in vivo - like pathophysiology observed in this system suggests that it might serve as a useful tool for evaluating human - relevant renal toxicity in preclinical safety studies.
This lecture covers pathophysiology and emergent stabilization of diabetic ketoacidosis and hyperglycemic hyperosmolar syndrome
Alcohol - Induced Tissue Injury: Exploring Pathophysiology, Translational Developments and Experimental Models Used in Alcohol Research
Because cGVHD has a similar pathophysiology to some autoimmune diseases, it is likely that these findings will be useful for developing new treatments and preventive therapies in other conditions.
Authors examined the association between SVD and AD pathology by looking at magnetic resonance imaging (MRI)- based microbleeds (MB), white matter hyperintensities (WMH) and lacunes (which are measures for SVD) along with certain protein levels in cerebrospinal fluid (CSF) which reflect AD pathophysiology in patients with AD, VaD and healthy control patients.
The findings link the gene to a potential mechanism for ADHD pathophysiology.
Performing genetic studies in multiple human populations can identify disease risk alleles that are common in one population but rare in others, with the potential to illuminate pathophysiology, health disparities, and the population genetic origins of disease alleles.
Regulation of Gene Expression (Jason Mills and Andy Greene, co-Section Editors): This section focuses on manuscripts that use existing or novel high - throughput technologies to study, at the systems level, how gene products (RNA, protein) change in abundance during pathophysiology and / or development.
Animal models are necessary to develop improved diagnostics and therapeutics, as well as understanding the basic pathophysiology of common human laryngeal diseases.
Higher BPA levels in PCOS women compared to controls and a statistically significant positive association between androgens and BPA point to a potential role of this endocrine disruptor in PCOS pathophysiology.
It is not easy for the students to cope up with this assignment due to a tight deadline, hence our writers will always be there to provide pathophysiology help to nursing students.
Coursework ● Life Span Development ● Health Assessment ● Pathophysiology ● Therapeutic Communication ● Pharmacology for Nurses ● Cultural Competence in Health Care ● Psychiatric and Mental Health Nursing
Finally, we generate new tools and mouse models to study the role of de novo protein synthesis in normal brain function and in pathophysiology associated with neurodevelopmental and neurodegenerative disease.
Bladder Pathophysiology Laboratory: This laboratory focuses on projects related to bladder and female pelvic floor disorders.
Unfortunately, the associations between pathophysiology and problem behaviour have been reported only in a very limited number of scientific reports, or are largely theoretical, based on analogues from the human literature [51, 52].
Our results suggest that blocking the catalytic site of HDAC4 is insufficient to fully recapitulate the spectrum of biological functions that HDAC4 knock - down subserves in an HD context, whilst specifically improving some aspects of HD pathophysiology.
«Our study highlights the multifaceted pathophysiology of Dravet Syndrome that includes brain, heart, and autonomic disturbances, and suggests novel therapeutic strategies for interventions to reduce SUDEP in this and perhaps other severe epilepsies,» says David S. Auerbach, Ph.D., of the University of Michigan.
Colony collapse disorder (CCD) and bee age impact honey bee pathophysiology.
One distinct pathophysiology or disordered process is the occurrence of macrencephaly in some children with ASD, which is characterized by early neuronal overgrowth and abnormally enlarged brains.
Previous epidemiological surveys have shown that prevalence of hyperglycemia or metabolic syndrome in patients with BD was higher than that of the general population; hence, the researchers concluded that lipid abnormality may be involved in BD pathophysiology.
Seed of a Clematis vitalba shrub (also known as traveller's joy and old man's beard)(2x) Dark - field microscopy Viktor Sykora Institute of Pathophysiology First Faculty of Medicine Charles University Prague, Czech Republic
Identifying the molecular causes of disease represented a major breakthrough in the history of medicine, moving the discipline from pattern recognition and therapeutic strategies based on syndromic pathophysiology to molecular mechanism and evidence ‐ based therapies derived from clinical trials designed on the basis of molecular mechanism.
Platelet activating factor receptor and innate immunity: uptake of Gram positive bacterial cell wall into host cells and cell - specific pathophysiology.
I am currently exploring functions of BIN1 by generating mouse models to modify the levels of BIN1 expression in the brain, and investigating how altering the levels of this protein can modify AD - related pathophysiology.
We also focused on the possible link between costamere and CNM pathophysiology.
«Thanks to improvements in the understanding of AML biology, a multiplicity of so - called targeted therapies and therapies based on differential pathophysiology of leukemic stem cells compared with normal counterparts have emerged,» noted Richard M. Stone, MD, clinical director of the Adult Leukemia Program at Dana - Farber Cancer Institute in Boston, and colleagues, writing in a review for the ASCO 2017 Educational Book.
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