Sentences with phrase «pathway analysis of»

Pathway Analysis of the data was performed with Ingenuity Pathways Analysis (Ingenuity Systems, www.ingenuity.com).

To gain biological relevance of methylation differences in adipose tissue from unrelated patients with diabetes versus nondiabetic subjects, we performed a KEGG pathway analysis of the 7,046 genes that exhibit differential methylation at q < 0.15 (Supplementary Table 12) using WebGestalt.

By the end of 2009, I was involved heavily in pathway analysis of the array data.

The ECETOC Young Scientist Award at the European Societies of Toxicology (Eurotox) Annual Congress (Rhodes, Greece, 5 - 8 October 2008) went to: Ms Nathalie Lambrecht of CARDAM VITO in Belgium for her poster, entitled «Pathway analysis of dendritic cell markers for skin sensitization.»

To make BinoX directly usable for other researchers, a public web server http://PathwaX.sbc.su.se (Ogris et al., 2016b) was set up for on - line pathway analysis of single gene sets, which applies the BinoX algorithm to all KEGG pathways and FunCoup networks.

Program impact pathway analysis of a social franchise model shows potential to improve infant and young child feeding practices in Vietnam

Not exact matches

Lacking a leader, «it's hard for me to be optimistic or pessimistic because I don't know if they're going to open the floodgates and take a lot of risks to rush the technology out — or if they're going to take a reasonable, rational pathway to protecting people,» said David Friedman, director of cars and product policy and analysis at Consumers Union.

GFI reports that as their scientists investigate further, they have become more optimistic — because clean meat is so much more efficient than animal - based meat.102 One of their senior scientists, Dr. Liz Specht, has met with venture capital firms and other venture investors to present technology plans of specific clean meat companies and their pathways to commercialization.103 GFI further reports that, based partly on her analysis, many leading venture capital investors and firms have become much more interested in clean meat companies.

Only a very small number of companies have set long - term (2030 or later) targets which can be considered to be in line with a sectoral 2 °C pathway.282 An analysis of 70 of the world's largest publicly listed corporate emitters, across the aluminium, cement, chemicals and electric utilities sectors, found that 21 had targets up to 2020 which could be considered consistent with a 2 °C sectoral pathway, but only 7 had targets to 2030 or later.283 Twenty others had non-2 °C or «irrelevant» targets, and the rest had none at all.

GFI reports that as their scientists investigate further, they have become more optimistic — because clean meat is so much more efficient than animal - based meat.102 One of their senior scientists, Dr. Liz Specht, has met with venture capital firms and other venture investors to present technology plans of specific clean meat companies and their pathways to commercialization.103 GFI further reports that, based partly on her analysis, many leading venture capital investors and firms have become much more interested in clean meat companies.

Analysis of signaling pathways that were affected pointed to changes in mitochondrial function and oxidative phosphorylation, consistent with a number of studies showing perturbations of these pathways in neurodegenerative disorders.

The Moores Cancer Center's Molecular Tumor Board brought together medical, surgical and radiation therapy oncologists, biostatisticians, radiologists, pathologists, clinical geneticists, basic and translational science researchers, and bioinformatics and pathway analysis specialists to discuss the intricacies of tumor genetics and tailor a personalized treatment plan for patients with advanced cancer or who have exhausted standard therapies.

Los Alamos National Laboratory conducts a wide range of biological research efforts as part of its national security science mission, with such research as phylogenetic analysis helping to determine safe pathogens and disease transmission pathways.?

Scientists from the Biogerontology Research Foundation (BGRF), a UK - based charity founded to support aging research and address the challenges of a rapidly aging population, propose a new concept for signalome - wide analysis of changes in intracellular pathways, called OncoFinder, which allows for accurate and robust cross-platform analysis of gene expression data.

To unravel the complex signaling pathway map, the scientists used their own findings from the analysis of factors regulated up or down in the interplay between tissue and stem cells, linking them with the signaling pathways described in existing literature.

Show how analysis of CSF samples from Alzheimer's disease patients has identified potential new biomarkers and provided new information about some of the major pathways involved in the disease

The analyses of genetic link to BMI indicate that the central nervous system has a role in obesity susceptibility, including a pathway that responds to changes in feeding and fasting and that is thought to be targeted by an FDA - approved weight - loss drug.

«It's a step up in the transgenic technology that's available in this model system that opens up new pathways of analysis.»

To help identify genes and signaling pathways that may be influenced by zinc, Knoell and his team performed a genome - wide microarray analysis of lung tissue taken from zinc - deficient mice with sepsis.

Putting together their analyses of the mitochondrial DNA in each tumour cell line and the metabolic pathways at work, the team were able to deduce how each cell line's genetics directly affected its ability to multiply.

«New tumor analysis method identifies high - risk prostate cancer: Cancer cells» genetic pathways show which patients are likely to develop aggressive types of the disease.»

The new study, a comprehensive analysis of the genomes of 178 primary cervical cancers, found that over 70 percent of the tumors had genomic alterations in either one or both of two important cell signaling pathways.

«Crosstalk analysis of biological networks for improved pathway annotation.»

The discovery was made during an analysis of the parasitic plant Viscum scurruloideum, a species of mistletoe whose apparent ability to survive and thrive without several genes involved in the primary energy - producing pathway of oxygen - respiring organisms could make it one of the most unusual plants on Earth.

«It is redefining the data analysis that will likely allow us to identify the right treatment pathway for each patient,» says Lisa Butterfield, president of the Society for Immunotherapy of Cancer (SITC).

In forensics, CUP might be used in reproducing bullet pathways, which could once again open up the Kennedy assassination conspiracy theories and revive a more accurate analysis of the strange physics of the «magic bullet.»

Developed by researchers in the UK and Germany and published in Nature Methods, OmniPath offers a comprehensive, unified collection of literature - curated signalling pathways based on an analysis of 41,000 scientific papers.

The geometrical structures and hydrogen - bond tunneling pathways of the water trimer, tetramer, pentamer, and hexamer systems have recently been characterized with global analysis of potential surfaces, diffusion Monte Carlo calculations, and far - infrared laser vibration - rotation tunneling spectroscopy.

Former Energy Department Assistant Secretary for Policy Susan Tierney, now a principal in the Boston - based Analysis Group, said regulations underway put the United States «well on the pathway... but many of them would need to be tightened up.»

Scientists performed an integrative transcriptomic analysis, comparing gene expression networks across all three groups of participants and finding unique molecular profiles and pathway enrichment patterns.

That requires analytical and bioinformatics tools to conduct disease or therapeutic association and pathway analysis that combines various forms of «omics data.

(C) Biochemical pathway impact analysis — males, The top five pathway disturbances in males were responsible for 82 % of the metabolic impact.

Evan Paull, a graduate student in Stuart's lab at UC Santa Cruz (now at Columbia University), led the computational analyses, which involved integrating the phosphoproteomic data with genomic and gene expression datasets to provide a unified view of the activated signaling pathways in late stage prostate cancer.

The results of this analysis identified a novel pathway and genetic mediator of metastasis for adenocarcinoma of the prostate, the androgen receptor gene.

Through the systematic analysis of ommochrome and porphyrin biosynthetic pathways, the authors identified several genes required for producing planarian pigment.

Western blot analyses with phospho - specific antibodies suggested that stretching induces phosphorylation of ERK of the MAP kinase pathway, but did not induce phosphorylation of phosphatidylinositol 3 - kinase.

A proteomics analysis revealed expression changes of 56 proteins, and a further protein pathway analysis suggested their association with the cell morphology, the organization, and the increased cellular movement and the proliferation.

«Analysis of metastatic prostate cancers suggests treatment options: Study maps out abnormal signaling pathways in prostate cancer cells and provides computational approaches to identify individualized targets for therapy.»

Gene expression analysis of the animals» skeletal muscles led to another clue: differences in the kynurenine pathway of tryptophan degradation.

Metabolomic profiling of vaccine candidates by SB measurement (LU): LU will analyse metabolic pathways based on samples from the above tasks and will extend the analyses to other project samples as well.

Kim et al. suggest that moving away from empirical research to either systems analysis or hypothesis driven approaches may advance our vaccinology understanding.5 Interrogation of peripheral blood responses following vaccination, termed «systems vaccinology», has led to the identification of immune signatures and pathways that are correlated to immune responses.

To study these pathways, we use a range of in vitro and in vivo approaches, including manipulating genes in mice and leveraging genome - wide analyses and chemical biology.

Used together, these technologies provide maximal statistical rigor to analyses of coregulation of genesets that are functionally related or related by involvement in a given biologic pathway.

Many functional categories of genes were represented in these analyses, including calcium signaling, cytokines, and growth factor pathways.

Our BN analysis methods can be used to identify novel gene interactions and networks for advanced study of different biological networks and pathways.

Birgit Kagermeier - Schenk (Weidinger, TUD)-- «Genome - wide analysis of Wnt / beta - catenin target genes in zebrafish embryogenesis and characterization of a novel modifier of Wnt signaling pathways» (2010)

Computational biologists: Download an integrated set of pathways in BioPAX format for global analysis.

The CCFA Genetics Initiative seeks to deliver validated pathway models of IBD disease mechanisms, new animal models for analysis and development, chemical probes of relevant pathways, new proteins and pathway targets, recruitment of new IBD investigators, and a tested paradigm for rapid analysis and cure for Crohn's disease.

NEWARK, Calif., May 31, 2016 (GLOBE NEWSWIRE)-- StemCells, Inc. (NASDAQ: STEM)(the «Company») today announced its decision to terminate the Company's Phase II Pathway Study in spinal cord injury following an in - depth review of data from the study and after obtaining the concurrence of the study's Interim Analysis Data Monitoring Committee (the «IA - DMC»).

Analysis of gene expression array in TSC2 - deficient AML cells reveals IRF7 as a pivotal factor in the Rheb / mTOR pathway.