Sentences with phrase «patient randomized study»

Not exact matches

Besides randomized controlled clinical trials, there are a number of ways researchers can study how a particular cancer treatment is playing out in the real world: there are retrospective studies, observational studies, and even prospective research done using patient registries.

The randomized study aimed to determine if the Medisafe smartphone app could improve self - reported medication adherence and blood pressure control among hypertension patients.

The study evaluated 344 patients and was randomized, with 321 receiving a study intervention; 163, angiotensin II; and 158, a placebo.

A 2001 double - blind study at the Mayo Clinic randomized 799 discharged coronary surgery patients into a control group and an intercessory prayer group, which received prayers at least once a week from 5 intercessors per patient.

In 1998 Fred Sicher et al. performed a small scale double - blind randomized study of 40 patients with advanced AIDS.

A randomized, blinded study of the impact of intercessory prayer on spiritual well - being in patients with cancer.

Methods: This randomized, double - blind, placebo - controlled, prospective follow - up study involved 90 coeliac disease patients in remission randomized to consume glucose syrups, maltodextrins or placebo for 24 weeks.

He points to research by a Stanford University researcher, Allan K. Mishra, who has studied PRP for years, whose in his most recent published research includes a large multicenter study [8] involving a host of well - respected orthopedic surgeons around the country who followed 230 patients in a double - blind randomized control study [the gold standard for medical research].

You can not randomize patients in a homebirth study, and you don't need to in order to determine whether homebirth is safe.

According to a report from the National Cancer Institute, a study of 30 randomized studies found that THC (the active ingredient in marijuana) extracts outperformed traditional anti-nausea drugs and helped patients gain weight.

When the researchers gave concentrated broccoli sprout extracts to 97 human type 2 diabetes patients in a 12 - week randomized placebo - controlled trial, obese participants who entered the study with dysregulated disease demonstrated significantly decreased fasting blood glucose levels compared to controls.

The REACT (Randomized Evaluation of an Algorithm for Crohn's Treatment) study, led by Robarts Clinical Trials at Western University (London, Canada) provides valuable new insights for community gastroenterologists which should benefit patients.

The study, conducted at 29 sites in 10 countries, included patients with rectal cancer who were randomized to robotic - assisted (n = 237) or conventional (n = 234) laparoscopic rectal cancer resection.

Since randomized clinical trials — the gold - standard in research — don't accommodate patients» preferences, Zoellner and her research team used a study design called a «doubly randomized preference trial» to investigate whether giving patients a choice affects their treatment outcomes.

Another problem is that modeling studies, like this one, are inherently less powerful than other kinds of medical research: randomized clinical trials, the gold standard in medical research, in which patients are randomly assigned different treatments or no treatment; case - control studies, which compare patients who have a condition with those who do not; or cohort studies, which determine the risk of contracting a disease by studying a group of people with similar demographics.

The randomized, placebo - controlled study, Familiar Auditory Sensory Training (FAST), enrolled 15 patients with traumatic closed head injuries who were in a vegetative or minimally conscious state.

«While randomized clinical trials are needed to test whether this is a causal relationship, these findings indicate doctors should consider using or re-starting ACEIs and ARBs as first - line blood pressure medications for patients undergoing peritoneal dialysis,» said Jenny I. Shen, MD, an LA BioMed researcher and corresponding author of the study.

In devising their experiment, the researchers took advantage of ambulance company practices that essentially provided a randomized group of patients to study, making it possible to compare outcomes at different hospitals.

In a multi-centre gastrointestinal surgery study, first - time idiopathic pancreatitis patients were randomized into a surgery group and a control group..

A randomized phase III trial finding that a new monoclonal antibody, elotuzumab, added to standard therapy, extended the duration of remission for patients with relapsed multiple myeloma by about five months Findings from two phase III studies showing that children with Wilms tumor who have a specific chromosomal abnormality do better with a more intensive, augmented chemotherapy regimen

«For the first time in a randomized study, the strategy of catheter ablation for atrial fibrillation may be better than the current approach for these patients.

Researchers studied 315 randomized patients, who all completed the five year - follow - up.

The phase 2 study included patients with ADPKD who were randomized 1:1:1 to bosutinib 200 mg / day, bosutinib 400 mg / day, or placebo.

The study was a randomized phase II trial testing whether the addition of local treatment, in the form of consolidative radiation therapy, to the standard treatment of systemic therapy improved progression - free survival for patients with limited metastatic NSCLC.

«This is the first study to show that a systemic therapy provides significant clinical benefit in a randomized fashion to advanced uveal melanoma patients, who have very limited treatment options,» said Richard D. Carvajal, MD, a medical oncologist at Memorial Sloan - Kettering and lead author on the study.

Dr. Bachhuber and coauthors conclude: «To fully understand the effect of medical cannabis on the use of other drugs, prospective longitudinal studies randomizing patients to cannabis versus other treatments are urgently needed.»

«There is a significant possibility that local therapy, such as consolidative radiation, may become an important part of the management of limited metastatic NSCLC patients, but this validation must take place in randomized phase III studies.

A total of 63 currently depressed patients, diagnosed with either major depressive disorder or bipolar disorder, participated in the study and were randomized to receive a single 20 - minute treatment of real LFMS or sham LFMS, where the device was on but the electromagnetic fields were inactive.

The study randomized 20 patients with major depressive disorder to ketamine (a single 50 mg dose) or saline in a double - blind, crossover study.

The data safety monitoring board of the trial, as mandated by the study protocol, continues to monitor outcomes in patients with a Recurrence Score of 11 to 25 randomized to chemo - endocrine therapy or endocrine therapy alone.

Motivated by their previous finding of the presence of P - glycoprotein overexpression in the nasal lining of patients with CRS with nasal polyps, the study authors conducted a randomized, double - blind, placebo - controlled clinical trial studying the use of low - dose Verapamil in 18 patients with CRS with nasal polyps.

Our study is not a definitive randomized clinical trial, but it does suggest that we are over-testing and over-treating these patients.»

An analysis of diagnostic test results from the Prospective Multicenter Imaging Study for Evaluation of Chest Pain (PROMISE) trial — in which patients with stable chest pain were randomized to either anatomic or functional testing as an initial diagnostic strategy — showed that the presence and extent of coronary artery disease detected by CT angiography better predicted the risk for future cardiac events than did measures of exercise tolerance or restricted blood flow to the heart muscle.

Julia Lewis, MD (Vanderbilt University School of Medicine) and her colleagues in the Collaborative Study Group conducted a 441 - patient randomized clinical trial to test the potential of a compound called ferric citrate to bind phosphorus, increase iron stores, and reduce the usage of IV iron and ESAs.

The second cohort of 140 patients with human leukocyte antigen - matched unrelated donor transplants completed enrollment in November 2017, with data expected from this randomized double - blind arm of the study in the next six months.

In a randomized, phase 2 multi-center clinical study, led by Manisha Shah, MD of The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James), investigators tested the effectiveness of the targeted therapy drug, dabrafenib (pronounced «da bRAF e nib» and marketed as Tafinlar), given alone compared with the same drug given in combination with trametinib (pronounced «tra ME ti nib,» marketed at MeKinist) to treat a subset of advanced papillary thyroid cancer patients with B - raf mutations.

The randomized controlled study involved 146 patients who were discharged from the departments of medicine and surgery at UC Irvine Medical Center to nursing homes, from February 2014 to August 2015.

African - Americans and men reported the greatest levels of improvement, and the 79 patients who reported moderate levels of anxiety at baseline generally did well over the course of follow - up, whether they were later randomized to the study intervention or not.

The resveratrol clinical trial was a randomized, phase II, placebo - controlled, double blind study in patients with mild to moderate dementia due to Alzheimer's disease.

Hypertension is the most important treatable risk factor for cardiovascular disease, and while it is especially common in the elderly and in patients with chronic kidney disease (CKD), these are the least studied groups in randomized controlled trials examining the health effects of lowering blood pressure.

The study, published in the July issue of the journal Epidemiology, offers benefits over typically used randomized clinical trials, as such studies are often too small to identify rare side effects or may be performed in a group of patients who do not take other types of medications or have other conditions that could skew the drug's effect in a broader group following approval.

In the randomized study, patients were assigned to receive either intravenous metoprolol or a placebo treatment at the moment of diagnosis of a myocardial infarction during ambulance transit to the catheterization laboratory.

Patients in the study were randomized to ozanimod 0.5 mg, 1.0 mg, or placebo.

Some studies suggested that patients responded well, but they didn't have the controlled, randomized, and blinded design that allows researchers to be sure, says Simon Mardel, a medical officer working on SARS at the World Health Organization (WHO) in Geneva.

The researchers performed a follow - up study of 168 patients from a previous randomized trial evaluating a «practical intervention» to help smokers quit before surgery.

The study, a retrospective survival analysis, included 229 patients who participated in two randomized, controlled clinical trials focused on relief of constipation for patients receiving palliative care for various types of late - stage cancer and other terminal diseases.

Our results suggest the need for future studies involving long - term ambulatory cardiac monitoring to better delineate the risk associated with transient vs persistent perioperative AF, as well as randomized clinical trials to determine optimal strategies for antithrombotic therapy in patients with perioperative AF and a significant burden of other risk factors for stroke,» the authors write.

Since the outbreak exploded in August, researchers have vigorously debated how to set up Ebola drug and vaccine studies, with some advocating randomized controlled studies, in which one group of patients doesn't receive the drug, as the quickest way to get results.

The research, which appears online Aug. 1 in the journal Annals of Neurology, is the first study from a double - blind controlled randomized trial of an exon - skipping agent to provide conclusive proof based on the standard six - minute walk test used to measure muscle function in patients with Duchenne muscular dystrophy (DMD), the most common form of muscular dystrophy in children.

Together with Liberian officials, Lane is poised to launch a randomized study of an antibody cocktail called ZMapp; that study does include a control group in which patients will receive standard care but not the drug.