So this is almost a snapshot, a day in the life of
a patient with cognitive decline.
Six clinical trials that included a total of 454 patients found that Huperzine - A increased mental function in
patients with cognitive decline.
Not exact matches
Fernando Pagan, a GUMC associate professor of neurology who directs the Movement Disorders Program at MedStar Georgetown University Hospital, said that to his knowledge, the study «represents the first time a therapy appears to reverse — to a greater or lesser degree depending on stage of disease —
cognitive and motor
decline in
patients with these neurodegenerative disorders.»
Dr. Smith has previously shown that a walking exercise intervention for
patients with mild
cognitive decline improved
cognitive function by improving the efficiency of brain activity associated
with memory.
Ongoing studies at Uppsala University in Sweden have shown that the chemical agent dubbed Pittsburgh Compound - B, or PIB, is a highly accurate marker of plaque buildup and that its abundance in the brain can predict whether
patients with mild
cognitive impairment will develop Alzheimer's — and when that
decline will likely start.
However, whole - brain radiation has been associated
with a
decline in
cognitive functions that can negatively affect a
patient's quality of life.
Patients who had changed versions of this gene showed early promise, often attending college, but then experienced
cognitive decline consistent
with a degenerative disease.
In contrast,
patients with the best
cognitive performance before implantation showed stable postimplantation results, although there was a
decline in some
patients, according to the results.
Data from 304 PD
patients followed for up to 8 years indicate that
patients with higher cerebrospinal fluid (CSF) α - synuclein levels experienced faster
cognitive decline in the following months, although no associations were found between α - synuclein levels and motor changes.
Although several large studies have shown that α - synuclein levels are lower in the CSF of PD
patients and those
with related synucleinopathies compared to controls, its role in
cognitive decline and dementia had been unexplored.
Whole brain radiotherapy (WBRT) significantly improves tumor control in the brain after SRS, yet because of its association
with cognitive decline, its role in the treatment of
patients with brain metastases remains controversial.
Basak's laboratory, which is focused on
cognitive interventions to improve abilities that
decline with age, is conducting further research to evaluate differences among various types of video games, long - term effects of
cognitive training using the games, and effects on
patients already experiencing mild
cognitive impairment.
By stimulating this region of the brain, the Alzheimer's subjects
cognitive and daily functional abilities as a whole
declined more slowly than Alzheimer's
patients in a matched comparison group not being treated
with DBS,» he said.
They hope that early detection of these neurophysiological abnormalities and decreased function will help
with early identification of type 2
patients who are at the greatest risk for developing
cognitive decline or possibly dementia.
Led by staff scientist Keith Vossel, MD, the team of researchers used sophisticated technologies to detect «subclinical» epileptic activity (too subtle to be noticed on standard clinical exams) and showed that Alzheimer
patients with such activity had a faster
cognitive decline than those without.
Cognitive decline in elderly people can be caused by a specific and treatable metabolic disorder, and the use of laboratory tests is recommended as part of the diagnostic workup of
patients with dementia.
Abstract:
Cognitive decline in elderly people can be caused by a specific and treatable metabolic disorder, and the use of laboratory tests is recommended as part of the diagnostic workup of
patients with dementia.
«Therapeutic manipulation of repair factors such as BRCA1 may ultimately be used to prevent neuronal damage and
cognitive decline in
patients with Alzheimer's disease or in people at risk for the disease,» says senior author Lennart Mucke, MD, director of the Gladstone Institute of Neurological Disease.
The researchers» findings suggest that Nav1.1 levels in special regulatory nerve cells called parvalbumin cells, or PV cells, are essential to generate healthy brain - wave activity — and that problems in this process contribute to
cognitive decline in AD - mice and possibly in
patients with Alzheimer's.
An 18 - month trial of high doses of the same three vitamins used here showed a slowing of
cognitive decline in
patients with mild Alzheimer's disease, although not in
patients with moderate Alzheimer's disease [45].
Finally, combining the results of PET imaging of
declines in these different neuromodulator systems
with behavioral studies in
patients with Parkinson's disease and rodents
with experimental damage to those systems helps us understand how they contribute to both
cognitive deficits and the risk for falls.
His group has developed a new approach to the treatment of Alzheimer's disease, and this approach has led to the discovery of subtypes of Alzheimer's disease, followed by the first description of reversal of symptoms in
patients with mild
cognitive impairment and early Alzheimer's disease, with the ReCODE (Reversal of Cognitive Decline)
cognitive impairment and early Alzheimer's disease,
with the ReCODE (Reversal of
Cognitive Decline)
Cognitive Decline) protocol.
The researchers analyzed information from 100
patients who likely have Alzheimer's disease, 60
patients with mild
cognitive impairment, 100
with subjective
cognitive decline, and a control group of 26 healthy individuals.
Elderly
patients with dementia, or any other
patient in
cognitive decline, present a unique ethical dilemma.
Benefits of Mindfulness Training for
Patients With Progressive
Cognitive Decline and Their Caregivers.
Atorvastatin does not slow
cognitive decline in
patients with mild to moderate probable Alzheimer's disease who are taking donepezil