Not exact matches
Though they can't tell for sure from the data, the researchers say this suggest that
patients who had the thallium scans
were sent for further testing using the invasive angiography technique because the initial scan gave a
false positive for serious blockage.
Dr. Catalona, who
was the first physician in the U.S. to run the phi test, added, «However, the problem
is that higher levels of PSA can also
be caused by a benign enlargement or inflammation of the prostate, leading to many
false ‐
positives for cancer and ultimately unnecessarily invasive biopsies and an increased potential for
patient harm.»
Though the optimal scenario
is actually estimated to catch fewer lung cancers than the criteria used in the National Lung Screening Trial (NLST) in the US, the authors predict this more stringent scenario would require fewer CT scans, and lead to fewer
false positive screens and lung cancer overdiagnosis, which can lead to
patient harm.
The disease
is notoriously difficult to diagnose, leading to a large proportion of both
false positives — where
patients undergo surgery they don't need — as well as
false negatives — where appendicitis
is mistaken for gas or cramps and left untreated.
False positives were noted for three
patients.
On the plus side, Aisner points out, testing via circulating tumor DNA returns very few
false -
positives — when a test discovers DNA with a cancer - causing genetic change, it
is strong evidence that this alteration
is, in fact, present in the
patient's cancer.
Clinical examination and imaging technologies
are critical elements for detecting and diagnosing breast cancer, yet the high rate of
false positives and
false negatives resulting from these approaches can significantly impact
patient care.
And I
'm not seeing
patients that
are at the same level as you know,
being an athlete but I do try to keep them 48 hours away from strenuous workout so you don't get those
false positives.
He didn't allow me to speak much, but I did get in my favorite argument about scientists needing 95 % certainty to make claim and thus
being overly cautious (they need to avoid
false positives in order to protect their reputations — which
is understandable), while those living in the world (environmentalists, potential victims) would want to follow the «medical model» of avoiding
false negatives, and would
be concerned about possible problems at a much lower standard of certainty (a doctor would not tell her
patient that there
is only 94 % certainty the lump
is cancerous, so we won't operate).