It can also identify relatives of cancer
patients at increased risk of cancer and gives them a window of opportunity to decrease their cancer risk.
September 20, 2011 Food and drugs: Administer together A regulatory bias against taking oral anti-cancer medications with food places many
patients at increased risk for an overdose and forces them to «flush costly medicines down the toilet,» argues Mark Ratain, MD, an authority on cancer - drug dosing.
In collaboration with Vanderbilt's Family Cancer Risk Service, she established a clinic at the Breast Center to specifically serve
patients at increased risk for developing breast cancer.
Metabolic profiling has been shown to improve the identification of
patients at increased risk for cardiometabolic events.
This procedure may offer
patients at increased risk of colorectal cancer an alternative to colonoscopy that is less - invasive, better - tolerated, and with good diagnostic accuracy.
An interactive, practice - focused workshop for primary care providers that improves clinical skills in assessing genetic risk for cancer, ordering and interpreting genetic testing and managing
patients at increased risk for cancer.
«The substantial variation in prescribing patterns of such extremely addictive medications for minor injuries results in many thousands of pills entering the community, and places
patients at an increased risk of continued use and potentially addiction,» said lead author M. Kit Delgado, MD, MS, an assistant professor of Emergency Medicine and Epidemiology at Penn. «It's vital that we identify and understand the root causes of this growing issue.»
Psoriasis is a lifelong disease that is associated with significant cosmetic and physical disability and puts
patients at increased risk for many major medical disorders.
Not exact matches
Beyond the cardiovascular
risk associated with LDL - C, genetic, epidemiologic, clinical and real - world data suggest that
patients with elevated triglycerides (TG)(fats in the blood), and TG - rich lipoproteins, are
at increased risk for cardiovascular disease.
These
risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the
risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may
increase the amount of discount required on Gilead's products; an
increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror
patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured
patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or
at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the
risk that physicians and
patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other
risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
A new study published by researchers from the University of Illinois
at Chicago suggests that the drug oseltamivir — commonly known as Tamiflu — does not cause an
increased risk of suicide in pediatric
patients.
Patients with a history of heavier smoking are also
at increased risk, even if they have since quit smoking.
Too few
patients with retinal infarction, or loss of blood flow in the eye, are evaluated for stroke
risk or seen by a neurologist, putting them
at increased risk for another stroke, according to preliminary research presented
at the American Stroke Association's International Stroke Conference 2018, a world premier meeting dedicated to the science and treatment of cerebrovascular disease for researchers and clinicians.
Instead of laying
patients flat, nurses keep them elevated
at a 30 - degree angle, which studies show is better for the lungs and does not, as previously thought,
increase the
risk of bedsores.
Breast cancer
patients may be
at an
increased risk of cardiovascular diseases including heart failure and may benefit from a treatment approach that weighs the benefits of specific therapies against potential damage to the heart, according to a new scientific statement from the American Heart Association published in its journal Circulation.
Dr Hashimoto said: «Hemodialysis
patients are
at increased risk of sudden cardiac death because they often have latent ischaemic heart disease which reduces blood flow to the heart.
«Healthy
patients with elevated calcium and plaque burden are
at increased risk of experiencing adverse cardiovascular events in even a short period of just three years.»
Researchers found that
patients with 2 or 3 abnormal measures were
at 145 times
increased cardiac
risk.
Based on recent laboratory work demonstrating that major depressive disorder is associated with
increased systemic inflammation, the team of researchers hypothesized that psoriasis
patients who develop depression are
at increased risk of subsequently developing psoriatic arthritis.
Hemodialysis
patients who had 2 or 3 abnormal measures were
at 145 times
increased risk.
Charging that thousands of
patients are being misled and may be unnecessarily placed
at increased risk of death, a U.S. watchdog group last week demanded that federal regulators suspend a major clinical trial exploring when to offer blood transfusions after a heart attack.
Dravet
patients usually develop moderate to severe cognitive delays and some features of autism, and are
at increased risk of SUDEP (sudden unexplained death in epilepsy).
Many studies show that these
patients are
at increased risk of infertility and are less likely than normal - weight women to conceive after fertility treatment.
«We need systems of care that better identify these
patients who are
at increased risk because getting that follow - up can significantly reduce their
risks of heart attack or premature death.»
Statistical analyses showed that
patients with a BMI > 25, those with a fatty liver, and those older than 60, were
at increased risk of having a colon polyp.
This helps shed light on why brain injury
patients seem to be
at increased risk of dementia — and may help us develop treatments that reduce this
risk.»
As well,
patients who score higher on the CHADS2 score, a rule used by physicians to determine a
patient's
risk of stroke, are
at increased risk of stroke with or without atrial fibrillation.
Led by Brenda Penninx, PhD, of the VU University Medical Center in Amsterdam, the Netherlands, the study found that
patients with an early age
at onset and higher symptom severity have an
increased genetic
risk for MDD, bipolar disorder and schizophrenia.
When the investigators looked
at patients» pre-transplant characteristics, they found that high body mass index and cirrhosis caused by alcohol consumption were linked with an
increased risk of developing steatosis.
They also discovered that compared with healthy controls,
patients with first episode schizophrenia had higher levels of insulin and
increased levels of insulin resistance, again supporting the notion that this group are
at higher
risk of developing diabetes.
Ibuprofen is associated with
increased blood pressure and hypertension compared to celecoxib in
patients with osteoarthritis or rheumatoid arthritis and
increased risk of cardiovascular disease, according to late - breaking results from the PRECISION - ABPM study presented today in a Hot Line Session
at ESC Congress1 and published in EHJ.
New research suggests these
patients may be
at increased risk of an unusual and aggressive form of skin cancer.
Medicare
patients 65 years old or older were not found to be
at increased risk for ODO.
All
patients had evidence of, or were
at increased risk for, coronary artery disease.
In a report on the research, published in the December 27 issue of JAMA Dermatology, the researchers call on physicians who treat women with central centrifugal cicatricial alopecia (CCCA) to make
patients aware that they may be
at increased risk for fibroids and should be screened for the condition, particularly if they have symptoms such as heavy bleeding and pain.
In a related editorial comment, Paolo Boffetta, M.D., M.P.H., associate director for population sciences
at The Tisch Cancer Institute and chief of the Division of Cancer Prevention and Control of the
at Mount Sinai in New York, addressed whether the
increased risk of cancer in this group of heart failure
patients warranted additional screening beyond what was recommended for the general public.
Both spouses and first - degree relatives of
patients with celiac disease are
at increased risk of nonceliac autoimmune disease, according to a study in the July issue of Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association.
Citalopram, the most commonly prescribed drug among
patients in the study, was not associated with an
increased risk of arrhythmia, even
at higher doses.
Many years ago clinicians began noticing that
patients with sleep apnea were
at an
increased risk of developing complications after operations.
«Following our research, it is important that clinicians treating
patients with Type 2 diabetes are aware that their
patients who also have OSA are particularly
at increased risk of developing advance retinopathy and, hence, appropriate preventative measures should be put in place.
This group of researchers previously looked
at increased risk of cancer among heart failure
patients and showed a 70 percent
increase in
risk.
Professor Mary Morrell, co-principal investigator of the study from the National Heart and Lung Institute
at Imperial College London, said: «Sleep apnoea can be hugely damaging to
patients» quality of life and
increase their
risk of road accidents, heart disease and other conditions.
«Providers who care for rural
patients must recognize that these
patients may be
at an
increased risk for financial impact.
Obese
patients were
at increased risk of both types of reoperation.
It had become clear that
patients in post-market trials were
at increased risk for heart attack and stroke —
risks about which drugmaker GlaxoSmithKline knew but had not informed
patients.
«While we can't guarantee that the partners of
patients will not develop oral HPV infections or cancers, we can reassure them that our study found they had no
increased prevalence of oral infections, which suggests their
risk of HPV - related oral cancer remains low,» says Gypsyamber D'Souza, Ph.D., M.P.H., associate professor of epidemiology
at the Johns Hopkins University Bloomberg School of Public Health.
Scientists are reporting a test which can predict which
patients are most
at risk from aggressive prostate cancer, and whether they suffer an
increased chance of treatment failure.
Breast cancer
patients who are positive for the HER2 gene may be
at increased risk for heart damage during chemotherapy, according to a new study published in ecancermedicalscience.
«Our study showed that
patients with AF, especially women and African - Americans, are
at an
increased risk of heart attack compared to those without AF.»
«Our analysis of a national dataset shows that the
risk for endophthalmitis is no higher with Avastin and hints that there may actually be a lower endophthalmitis
risk compared to Lucentis, so the proposed FDA restrictions for Avastin might have the unintended consequence of
increasing the infection
risk for
patients,» said senior author Brian L. VanderBeek, MD, MPH, an assistant professor of Ophthalmology
at Penn..