Sentences with phrase «patients experimental therapies»

Not exact matches

Kite Pharma, one of the companies chasing a new generation of cancer drugs called chimeric antigen receptor T - cell (CAR - T) therapies, announced a patient death in a clinical trial of its experimental KTE - C19.

REINVENTING THE CLINICAL TRIAL Research Track Traditional clinical trials ask one question: Does an experimental treatment work better than nothing at all — or, the very least, the standard therapy offered patients.

Now, Emily has remained cancer - free for almost five years and her parents have created a foundation to help other patients access experimental cancer therapies.

The experimental device is being tested in cancer patients to see whether it can be tuned to accurately measure tumor shrinkage in response to therapy.

«Using Streptozotocin - induced type I diabetes and cornea epithelial wounding experimental models, we made novel observations that may soon lead to innovative therapies to treat DPN and ulcerations of the cornea and skin in diabetic patients,» said Yu.

Luznik says that the researchers» next step will be to test the short course therapy in a phase III randomized clinical trial that would directly compare results in patients who receive the cyclophosphamide treatment with those who receive either a separate, experimental approach to prevent GVHD or the more traditional six - month immunosuppressive therapy.

«It may sound like an appealing idea to allow seriously ill patients accelerated access to experimental therapies,» Sally Temple, the president of the International Society for Stem Cell Research, wrote to Texas lawmakers this month.

The study, «AKR1B1 promotes basal - like breast cancer progression by a positive feedback loop that activates the EMT program,» which has been published in The Journal of Experimental Medicine, suggests that an inhibitor of this enzyme currently used to treat diabetes patients could be an effective therapy for this frequently deadly form of cancer.

But for now, its top target is stopping HB 3236, which would open the door to patients paying for experimental therapies.

This episode highlights a growing challenge for patients: how to temper enthusiasm for experimental therapies, now widely and effectively marketed through personal testimonials posted online, until evidence shows that the treatments are likely to do more good than harm.

However, if there is no approved treatment for an ailment, the FDA has a compassionate therapy exception that allows the patient to agree to try an experimental approach.

Gene therapy death The Food and Drug Administration stopped a gene therapy trial this week after a patient undergoing the experimental treatment for a severe form of arthritis had a fatal reaction.

After seeing promising results in phase 1 of the Pediatric Leukemia Adoptive Therapy (PLAT - 02) trial with 93 percent of patients with relapsed or refractory acute lymphoblastic leukemia (ALL) achieving complete initial remission, researchers at Seattle Children's are continuing their quest to improve the experimental therapy and reduce the rate of relapse, which is about 50 pTherapy (PLAT - 02) trial with 93 percent of patients with relapsed or refractory acute lymphoblastic leukemia (ALL) achieving complete initial remission, researchers at Seattle Children's are continuing their quest to improve the experimental therapy and reduce the rate of relapse, which is about 50 ptherapy and reduce the rate of relapse, which is about 50 percent.

Two patients that had previously not responded to available standard treatments, including surgery, external radiation, hormonal and chemotherapy, have received 225Actinium - PSMA - 617 as experimental therapy.

In study results recently published online in Experimental Neurology, breathing function improved in patients after gene therapy, compared to a period of treatment with breathing exercises before the gene therapy.

Since 2011, though, experimental CAR T cell treatments for B cell leukemias and lymphomas — cancers in which patients» healthy B cells turn cancerous — have been successful in some patients for whom all standard therapies had failed.

Their winning work involved gene therapy, an experimental technique in which genes are inserted into patients to replace mutated genes that are causing disease.

As stakeholders in cellular therapy, the undersigned professional organizations believe it is necessary to share the following important message with patients and families contemplating cell therapy or experimental stem cell procedures.

Cell therapy, as envisaged by the teams of I - Stem, is primarily based on the identification of experimental protocols that can specifically guide differentiation of pluripotent cells to a cell fate, which presents a interest for the replacement of the defective cell population from the patient (the striatal neurons for Huntington's disease, the cells of the retinal pigment epithelium for retinitis pigmentosa, keratinocytes for genodermatoses, etc.).

Patients who participate in testing experimental stem cell therapies, whether in regulated clinical trials or from clinics offering unproven therapies, are pioneers.

Our clinicians direct the clinical operations of the Children's Health NONC (neuro - oncology) program and are members of the Children's Oncology Group (COG), a national childhood brain tumor consortium that provides our patients access to experimental therapies and new treatment developments.

Specially - marked Centers of Excellence feature comprehensive care teams that meet every patient need and provide access to clinical trials and experimental therapies.

«The development of a functional human kidney glomerulus chip opens up an entirely new experimental path to investigate kidney biology, carry out highly personalized modeling of kidney diseases and drug toxicities, and the stem cell - derived kidney podocytes we developed could even offer a new injectable cell therapy approach for regenerative medicine in patients with life - threatening glomerulopathies in the future,» said Ingber.

Experimental results from this study could potentially lead to new therapies for lowering eye pressure in patients with primary open - angle glaucoma.

Clinic will allow researchers to conduct twice as many immunotherapy trials, enable intensive patient monitoring to improve experimental therapies

Gene therapy, or an experimental technique that uses genes to treat disease, is currently being used to help patients who, even just a few years ago, had no options.

When a shady figure offers him a cure in the form of experimental therapy (which, as chance would have it, affords the patient super powers), he reluctantly seizes the opportunity.

On this point, if the scientific evidence is inconclusive on the matter of a therapy's effectiveness, patients seeking these experimental treatments may be unable to tender compelling evidence that their physical pain is increased by the denial of coverage for that treatment.

These services would include therapies that are necessary to extend life or ease pain, and also, arguably, experimental therapies that, while unproven, are reasonably anticipated by patients to have some positive effects.