All but one
patient in the study received chemotherapy for a median of six cycles.
Patients in the study received dupilumab or placebo added to their regular, twice daily dose of fluticasone / salmeterol.
The first
patients in the study received lower doses.
Patients in the study received electroacupuncture three to five times per week over eight weeks, which might be a burden for some people, the study authors acknowledged.
Not exact matches
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth
in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures
in European countries that may increase the amount of discount required on Gilead's products; an increase
in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift
in payer mix to more highly discounted payer segments and geographic regions and decreases
in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations
in ADAP purchases driven by federal and state grant cycles which may not mirror
patient demand and may cause fluctuations
in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured
patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials
in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations
in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates
in the timelines currently anticipated; Gilead's ability to
receive regulatory approvals
in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and
patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical
studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta
in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes
in its stock price, corporate or other market conditions; fluctuations
in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time
in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
The double - blind
study (meaning neither the researchers nor the
patients know if they are
receiving the coconut oil or placebo) at the Byrd Alzheimer's Institute, located
in Tampa, Florida, will be eight months long and will enroll about 65 people with mild to moderate Alzheimer's disease.
In response to reports that women may be using this unapproved drug, to increase milk production (lactation), the WHO and FDA are warning breastfeeding women of safety concerns as «there have been several published reports and case studies of cardiac arrhythmias, cardiac arrest and sudden death in patients receiving an intravenous form of domperidone that has been withdrawn from the market in a number of countries.&raqu
In response to reports that women may be using this unapproved drug, to increase milk production (lactation), the WHO and FDA are warning breastfeeding women of safety concerns as «there have been several published reports and case
studies of cardiac arrhythmias, cardiac arrest and sudden death
in patients receiving an intravenous form of domperidone that has been withdrawn from the market in a number of countries.&raqu
in patients receiving an intravenous form of domperidone that has been withdrawn from the market
in a number of countries.&raqu
in a number of countries.»
While the researchers did not directly compare survival rates and neurological outcomes with whether individual
patients received bystander CPR or defibrillation, they did find increases
in both over the duration of the
study.
Of the
patients who
received the high dose
in study, 11
patients are able to speak, 11
patients are fed orally and seven do not require bi-level positive airway pressure as of the data cut - off (August 7, 2017).
One example: A high number of
patients in the new
study had
received CPR and therefore a restored heartbeat sooner.
In the
study, 64
patients received the topical ocular insert containing the glaucoma drug bimatoprost.
The
study found that OSI resulted
in 781 fewer
patients each month
receiving both an opioid and a benzodiazepine.
Despite the advent of a new generation of stents,
patients with multiple narrowed arteries
in the heart who
received coronary artery bypass grafting fared better than those whose arteries were opened with balloon angioplasty and stents
in a
study presented at the American College of Cardiology's 64th Annual Scientific Session.
Results presented today at The International Liver Congress ™ 2015 demonstrate that hepatitis C (HCV)- infected genotype - 3 (GT - 3)
patients, with and without cirrhosis,
receiving 24 weeks of sofosbuvir (SOF)
in combination with ribavirin (RBV) and peginterferon (PEG) achieved the highest sustained virologic response rates at 12 weeks (SVR12), observed
in a Phase 3
study, to date.
The idea to specifically
study this group of
patients was based on groundbreaking research Garon published
in the New England Journal of Medicine last year, which found that among
patients who
received pembrolizumab, those with PD - L1 expression on at least 50 percent of their cancer cells showed the longest survival and disease control.
In the new study, patients receiving angioplasty with the new stents had a 47 percent higher risk of one of the outcomes identified as a primary endpoint in the study: death, heart attack and subsequent procedure to clear blocked arteries, as compared to patients who received bypas
In the new
study,
patients receiving angioplasty with the new stents had a 47 percent higher risk of one of the outcomes identified as a primary endpoint
in the study: death, heart attack and subsequent procedure to clear blocked arteries, as compared to patients who received bypas
in the
study: death, heart attack and subsequent procedure to clear blocked arteries, as compared to
patients who
received bypass.
In a 2010 study, Maria Semkovska and Declan M. McLoughlin of Trinity College in Dublin reviewed 84 studies of 2,981 patients who received EC
In a 2010
study, Maria Semkovska and Declan M. McLoughlin of Trinity College
in Dublin reviewed 84 studies of 2,981 patients who received EC
in Dublin reviewed 84
studies of 2,981
patients who
received ECT.
One of the
studies, published
in 2008, suggested that
patients whose antiretroviral treatment was deferred until their CD4 cell counts were below 250 were at greater risk of opportunistic infection than those that
received antiretroviral treatment when CD4 cell counts were higher than 350.
In this study in a Berlin hospital, one patient in five receiving routine care suffered from postoperative delirium, whereas in the group receiving support from delirium liaison nurses, fewer than 1 in 20 developed cognitive disorder
In this
study in a Berlin hospital, one patient in five receiving routine care suffered from postoperative delirium, whereas in the group receiving support from delirium liaison nurses, fewer than 1 in 20 developed cognitive disorder
in a Berlin hospital, one
patient in five receiving routine care suffered from postoperative delirium, whereas in the group receiving support from delirium liaison nurses, fewer than 1 in 20 developed cognitive disorder
in five
receiving routine care suffered from postoperative delirium, whereas
in the group receiving support from delirium liaison nurses, fewer than 1 in 20 developed cognitive disorder
in the group
receiving support from delirium liaison nurses, fewer than 1
in 20 developed cognitive disorder
in 20 developed cognitive disorders.
For one thing, they point out, acupuncture
studies are extremely difficult to double - blind — a methodological approach
in which neither the researchers nor
patients know who is
receiving the treatment under investigation and who is
receiving the placebo or sham.
Throughout the
study period, a significant increase occurred
in the proportion of
patients receiving bystander - initiated CPR, from 39.3 percent
in 2010 to 49.4 percent
in 2013.
Dr. Glen Weiss, M.D., M.B.A., is the first author of the
study abstract: Phase Ib / II Study of Pembrolizumab plus Chemotherapy in Advanced Cancer: Results of lung cancer patients receiving (at least) 1 prior line of the
study abstract: Phase Ib / II
Study of Pembrolizumab plus Chemotherapy in Advanced Cancer: Results of lung cancer patients receiving (at least) 1 prior line of the
Study of Pembrolizumab plus Chemotherapy
in Advanced Cancer: Results of lung cancer
patients receiving (at least) 1 prior line of therapy.
The cinnamon
study, published
in DiabetesCare, is the first to look at cinnamon
in Americans with type 2 diabetes.The
patients received 1,000 milligrams of cinnamon a day for three months.
In addition, on average, patients receiving nivolumab reported that their quality of life remained stable or improved throughout the study, while those in the chemotherapy group reported a declin
In addition, on average,
patients receiving nivolumab reported that their quality of life remained stable or improved throughout the
study, while those
in the chemotherapy group reported a declin
in the chemotherapy group reported a decline.
During the time covered
in the
study, Hansen said, 86.3 percent of
patients received CPR before EMS arrived, with 45.7 percent initiated by bystanders and 40.6 percent by first - responders.
Many
patients with ulcerative colitis don't
receive recommended testing and treatment for the common problem of iron deficiency anemia, reports a
study in the October issue of Inflammatory Bowel Diseases, official journal of the Crohn's & Colitis Foundation of America (CCFA).
In this study, the participating healthcare systems had a combined 7.5 million patients age 18 or older, with about 1.2 million patients receiving a psychiatric diagnosis in 201
In this
study, the participating healthcare systems had a combined 7.5 million
patients age 18 or older, with about 1.2 million
patients receiving a psychiatric diagnosis
in 201
in 2011.
For anxiety, there is one
study of 24
patients with social anxiety
in which half
received a single dose of cannabis derivative and scored their anxiety doing a simulated presentation.
To ensure that
patients can
receive all recommended care, we need to recognize the financial burden of cancer and identify
patients at risk for financial concerns,» says lead
study author Christine M. Veenstra, M.D., M.S.H.P., clinical lecturer
in hematology / oncology at the University of Michigan Medical School.
«Although we observed that short - term use of LDX was well tolerated and effective
in several subjective and objective areas, long - term
studies of menopausal women
receiving LDX are needed, similar to those conducted for ADHD
patients,» said Epperson.
The U.S. Department of Defense, which
received a congressional windfall of $ 80 million to research regenerative medicine
in 2008, is funding a team of scientists based at the University of Pittsburgh's McGowan Institute for Regenerative Medicine to oversee an 80 -
patient study of ECM at five institutions.
People who
received prescriptions for opioid painkillers
in the months before elective abdominal operations had longer hospital stays, and a higher chance of needing follow - up care
in a hospital or rehabilitation facility, than
patients who weren't taking such medications before they had the same operations, the
study finds.
The
study examined 328
patients with cervical cancer and 1,312 controls, matched on age and decade, who enrolled
in a hospital - based case - control
study drawn from 26,831
patients who
received treatment at Roswell Park Cancer Institute and completed the
Patient Epidemiology Data System questionnaire between 1982 and 1998.
The researchers analyzed the samples using immunohistochemistry and RNA sequencing to
study the changes
in the tumor immune microenvironment of
patients who
received and did not
receive chemotherapy, and changes before and after chemotherapy.
Among
patients with hypertension at high risk of cardiovascular disease, a program that consisted of
patients measuring their blood pressure and adjusting their antihypertensive medication accordingly resulted
in lower systolic blood pressure at 12 months compared to
patients who
received usual care, according to a
study in the August 27 issue of JAMA.
«However, our
study showed that
in the real world over a third of the
patients with STEMI undergoing transradial PCI who
receive heparin and about a fifth of
patients who
receive bivalirudin also
receive GPIIb / IIIa inhibitors.»
In the new study, to test whether the same observation was true in humans, Dr. Rostami and colleagues tested blood samples of patients with MS who had not yet received therapy, and those currently being treated with INF - β, a commonly used therap
In the new
study, to test whether the same observation was true
in humans, Dr. Rostami and colleagues tested blood samples of patients with MS who had not yet received therapy, and those currently being treated with INF - β, a commonly used therap
in humans, Dr. Rostami and colleagues tested blood samples of
patients with MS who had not yet
received therapy, and those currently being treated with INF - β, a commonly used therapy.
Patients with multiple health issues and who are at higher risk of adverse events are less likely to
receive follow - up care from a physician after visiting an emergency department for chest pain, reports a
study published
in CMAJ (Canadian Medical Association Journal)
The Chronic Hepatitis Cohort
Study is an analysis of records from a large, geographically and racially diverse group of 9,783
patients receiving care at four large U.S. health systems: Henry Ford Health System
in Detroit; Kaiser Permanente Northwest
in Portland, Oregon; Kaiser Permanente
in Honolulu and Geisinger Health System
in Danville, Pennsylvania.
A new
study led by researchers at Boston Medical Center (BMC) found that the proportion of discharges among minority
patients receiving inpatient care at minority - serving hospitals
in Massachusetts increased after the implementation of health insurance reform measures which expanded access to care
in non-safety net hospitals.
The
study, entitled COMET (Comparison of Operative to Medical Endocrine Therapy) for low - risk ductal carcinoma
in situ,
received funding through a $ 13.4 million, five - year award from the
Patient - Centered Outcomes Research Institute (PCORI), an independent, nonprofit organization authorized by Congress
in 2010 to support research that enlightens health care decisions.
A total of 63 currently depressed
patients, diagnosed with either major depressive disorder or bipolar disorder, participated
in the
study and were randomized to
receive a single 20 - minute treatment of real LFMS or sham LFMS, where the device was on but the electromagnetic fields were inactive.
«While Massachusetts safety - net hospitals (many of which are minority - serving)
received large cuts
in payments with the idea that other hospitals would assume the care of previously uninsured
patients, this
study demonstrates the importance of securing the future of safety - net and minority - serving hospitals through policy - based interventions to assure the continued care of vulnerable and underserved
patient populations.»
However, a new
study conducted at Manchester Royal Eye Hospital and published
in the American Journal of Ophthalmology, demonstrates high levels of undiagnosed anxiety and depression persisting
in patients receiving treatment, despite their improved visual outcomes.
We are proud to support this
study, which is one of the first of its kind
in the UK to investigate the experience of
patients with wet AMD
receiving anti-VEGF therapy.
Prior
studies that examined the impact of cancer treatment decisions on employment showed that
patients who
received chemotherapy were most likely to experience longer disruptions
in or loss of employment, but changes
in breast cancer management
in recent years have shifted recommendations away from chemotherapy for early stage breast cancer.
A
study of 343 post-surgical
patients treated by an innovative, multidisciplinary hospital - integrated pain program at Toronto General Hospital (TGH), University Health Network (UHN) found that all
patients showed reductions
in pain and anxiety
in the two - year
study, but those who also
received psychological services had greater reductions
in opioid use, and their mood improved.
In the
study of 512 prostate cancer
patients that led to Provenge's approval, one - third of the vaccinated
patients remained alive after three years, compared with one - quarter of those who
received a placebo shot, for an average life extension of four months.
In their recent
study, the researchers took a retrospective look at 697
patients who'd
received transplants at Seattle Cancer Care Alliance, Fred Hutch's clinical care partner, between 1993 and 2015 and who had also tested positive for rhinovirus.
In the new study, patients with a higher quality of life during their final days included those who avoided hospitalizations and stays in the intensive care unit (ICU), were not worried about death, prayed or meditated, received care at home, did not use a feeding tube, were visited by a pastor in the hospital or clinic, did not undergo chemotherapy in the final week of life, and felt an alliance with their oncologist regarding therap
In the new
study,
patients with a higher quality of life during their final days included those who avoided hospitalizations and stays
in the intensive care unit (ICU), were not worried about death, prayed or meditated, received care at home, did not use a feeding tube, were visited by a pastor in the hospital or clinic, did not undergo chemotherapy in the final week of life, and felt an alliance with their oncologist regarding therap
in the intensive care unit (ICU), were not worried about death, prayed or meditated,
received care at home, did not use a feeding tube, were visited by a pastor
in the hospital or clinic, did not undergo chemotherapy in the final week of life, and felt an alliance with their oncologist regarding therap
in the hospital or clinic, did not undergo chemotherapy
in the final week of life, and felt an alliance with their oncologist regarding therap
in the final week of life, and felt an alliance with their oncologist regarding therapy.