Not exact matches
«These splicing signatures could potentially be used as clinical biomarkers to detect blood stem cells that
show signs of early
aging or leukemia, and to monitor
patient responses to treatment,» said Crews.
Such clinical
signs can vary with patient age, with mean ages at diagnosis averaging between 2 and 5 years for dogs6 - 8 and 37 and 40 months for cats.2, 3 Signs can worsen if body weight is increased, articular cartilage damage is present, and if there is concurrent cranial cruciate ligament (CCL) rupture.9 Affected cats have shown signs of intermittent locking of the stifle after extension and can have a shuffling or crouching
signs can vary with
patient age, with mean
ages at diagnosis averaging between 2 and 5 years for dogs6 - 8 and 37 and 40 months for cats.2, 3
Signs can worsen if body weight is increased, articular cartilage damage is present, and if there is concurrent cranial cruciate ligament (CCL) rupture.9 Affected cats have shown signs of intermittent locking of the stifle after extension and can have a shuffling or crouching
Signs can worsen if body weight is increased, articular cartilage damage is present, and if there is concurrent cranial cruciate ligament (CCL) rupture.9 Affected cats have
shown signs of intermittent locking of the stifle after extension and can have a shuffling or crouching
signs of intermittent locking
of the stifle after extension and can have a shuffling or crouching gait.
Surgically treatable forms
of PSS are congenital — a defect at birth — so most
of these
patients» problems are recognized at a relatively young
age, through symptoms such as failure to grow, develop and / or thrive,
showing neurologic
signs, or having elevated liver enzymes or abnormal liver function («bile acids»).
Two populations
of animals
show clinical
signs of lameness: (1)
patients 5 to 10 months
of age, and (2)
patients with chronic degenerative joint disease.
Although dogs are the main
patients who usually start
showing signs at the
age of 12 to 36 months, cats are also affected but at a slighter older
age.
The test is stopped when
patients reach 80 %
of the estimated HRmax (220 -
age), when RPE ≥ 15 or when the
patient shows signs of distress during the test.