Sentences with phrase «patients slowed the progression»

According to a 2011 study published in the New England Journal of Medicine, sirolimus in selected patients slowed the progression of the disease and was associated with a reduction in symptoms and improved quality of life.

Not exact matches

For example, Eli Lilly & Co. (NYSE: LLY) has a phase 3 study of solanezumab under way in mild to moderate Alzheimer's disease patients that may slow disease progression by breaking up amyloid plaque buildups thought to be a major cause of the disease.

He contributes to other large - scale clinical trials including SAVE (evaluating whether treatment of obstructive sleep apnoea with continuous positive airways pressure can reduce the incidence of serious CV events in patients with established CVD), and CREDENCE, a randomised, double - blind, placebo - controlled trial assessing whether canagliflozin can slow the progression of diabetic nephropathy in patients with type 2 diabetes.

There's currently no treatment for Alzheimer's that can slow or stop the disease's progression, so catching it early can't currently improve a patient's outcome.

Next up: a larger trial in hundreds of patients to see if lowering mutant Htt protein slows progression of the disease, then a trial in healthy people who carry the mutant HTT gene to see if antisense treatments could prevent Huntington's altogether.

In patients with chronic kidney disease who are not on dialysis, ACEIs and ARBs slow the progression of diabetic nephropathy and reduce cardiovascular risk.

«This study also highlights the potential use of this anti-estrogen or miRNA in patients with recurrent prostate cancer, for whom there is no treatment, and raises the possibility of using anti-estrogen or miRNA treatments in preventing or slowing progression for primary prostate cancer.»

«Previous pilot studies researching the use of DBS in Alzheimer's have indicated the potential to slow cognitive decline in some patients, and have even shown metabolic changes in the brain that may slow the progression of the disease.»

While more research is needed to determine whether these approaches could help PD patients, Dr. Greenamyre is optimistic that one or both may ultimately make it into human clinical trials in an effort to slow or halt the otherwise inevitable progression of PD.

Their study of fecal samples from 105 patients treated with immune checkpoint blockade indicates that certain characteristics of patients» microbiomes correlate with slower disease progression while other qualities are associated with rapid worsening of the disease.

The Penn team also found that patients with this genetic variation had a slower rate of Parkinson's disease progression, and lower amounts of alpha - synuclein in the brain.

«The most important thing we can do is get the correct patients into clinical trials so we can tell, for example, whether it is a drug that is slowing the progression of the disease or the fact that we just happen to have a group of patients who have a slow progressing form of the disease.»

«This report provides evidence for the relevance of ALDH inhibition in Parkinson's disease pathogenesis, identifies pesticides that should be avoided to reduce the risk of developing Parkinson's disease and suggests that therapies modulating ALDH enzyme activity or otherwise eliminating toxic aldehydes should be developed and tested to potentially reduce Parkinson's disease occurrence or slow its progression particularly for patients exposed to pesticides,» the study states.

The TTUHSC El Paso research team now plans to test pharmacological compounds that can inhibit JNK3 in mice to identify drug compounds that will slow the progression of the disease and reduce the overall burden of this illness in patients.

«Not only is this the first study to associate fungi and liver disease,» said senior author Bernd Schnabl, MD, associate professor of gastroenterology at UC San Diego School of Medicine, «we might be able to to slow the progression of alcoholic liver disease by manipulating the balance of fungal species living in a patient's intestine.»

This makes our discovery promising, because even a small increase in the ATM activity induced by the SMRT drug can potentially translate to positive effects for patients, slowing disease progression and hopefully improving their quality of life.»

The research also indicates that a low protein, low salt diet may not only slows the progression of CKD as an effective adjunct therapy, but it can also be used for the management of uremia, or high levels of urea and other uremic toxins in the blood, in late - stage or advanced CKD and help patients defer the need to initiate dialysis.

New research into Amyotrophic Lateral Sclerosis (ALS)-- also known as motor neuron disease — shows that specific immune cells may help slow progression of the disease, an important step towards developing new therapies to treat patients.

Dr. Ready said the crossover at progression could have influenced the survival data; in fact, an analysis of six patients who crossed over to sunitinib showed that tumors that had been growing either slowed their growth or shrank following crossover.

Sometimes HD patients display symptoms at a drastically different time than expected based on the number of CAG repeats alone, suggesting that maybe other genetic or environmental factors speed up or slow down the progression of HD.

Boosting the activity of a protective gene and giving patients «good» gut bacteria could help prevent or slow progression of colorectal cancer, St. Jude Children's Research Hospital scientists have found.

Preliminary evidence from the small clinical trial, led by William Gillanders, MD, also suggests that the vaccine primed the patients» immune systems to attack tumor cells and helped slow the cancer's progression.

For patients with inflammatory bowel disease, medications — including steroids, immunosuppressants or anti-inflammatory drugs — are used to slow the progression of disease.

Citing slow progression of labor, doctors were requested to stop epidural pain control for 38 patients.

In addition, some RA patients take methotrexate to slow disease progression.

300 patients with Alzheimers, and those with their vascular risk factors treated showed significantly less decline; slowed progression of their disease.

The DIVINe study randomized two groups of patients with chronic kidney disease (CKD) to either placebo or vitamin B supplements with the hope of slowing down the progression of kidney disease.

Had it been identified early enough, the patient could take the necessary steps to slow or even halt its progression.

There are some examples of patients with Alzheimer's disease who were able to slow the progression of Alzheimer's taking large doses of coconut oil on a regular basis.

Patients with high urine protein loss may also benefi t from the use of angiotensin converting enzyme (ACE) inhibitors drugs, which will help to slow the progression of disease.

With appropriate assessment, therapy and monitoring, the progression of the disease can be slowed down and the severity of the symptoms reduced, giving patients comfort and a longer and better quality of life.

Additionally, we also stock pure and patented veterinary nutritional supplements that have been scientifically proven to relieve chronic pain and inflammation, as well as slow the progression of further arthritic changes in our patients» joints.

However, some studies have shown that low doses can be used safely over the long - term and may even slow the progression of chronic kidney disease in cats.3 Other medications like buprenorphine, tramadol, amantidine, gabapentin, and corticosteroids (e.g., prednisolone) have all been used to improve patient comfort in cats with arthritis.

There is currently no preventive measure for HCM itself, although early detection and treatment slows the progression of the disease, hopefully sparing the patient its more serious complications, such as FATE.

The good news is that the average patient with acquired laryngeal paralysis is at least 10 years old and the progression of the neurologic weakness is fairly slow.

Many canine cancer patients who are looking for everything they can do to slow progression switch their dogs to a real food diet, some even opt to feed raw as it is least inflammatory.

Take Home Facts: - Signs of osteoarthritis may be subtle and easy to miss - Early treatment is critical to slow progression of the disease - Maintaining lean body weight is absolutely critical for arthritic patients - Newer concepts of arthritis management involve proper exercise to maintain muscle mass and decrease pain - Structure - modifying agents are most effective when started -LSB-...]

Take Home Facts: - Signs of osteoarthritis may be subtle and easy to miss - Early treatment is critical to slow progression of the disease - Maintaining lean body weight is absolutely critical for arthritic patients - Newer concepts of arthritis management involve proper exercise to maintain muscle mass and decrease pain - Structure - modifying agents are most effective when...

This offers some pain relief for some patients, but does not slow the progression of the disease.

The trial shows that early treatment can slow progression of the disease, prolonging overall survival and helping patients remain symptom free for longer.

Therapeutics targeting microglia have slowed disease progression in rodent models, but have failed to translate into effective therapy for ALS patients.

Rehabilitation for patients with intracapsular repair is similar but slower in progression.

One of her early interests and publications was the use of metronomic low - dose protocols to help slow down cancer progression in patients that may not tolerate high - dose regimens or in cases where high - dose chemotherapy was not a feasible option.

«We now realize that even for patients that can not be cured of their cancer, we can often provide treatments that will control symptoms and slow disease progression so that they can live a good quality of life with cancer.»

The goal of dog medicine in pain management, such as when managing canine Osteoarthritis (OA) is to reduce clinical signs, slow the progression of the disease, and to improve the comfort of the patient.

In order to reduce the symptoms and slow the progression of the disorder, the patient may need to be placed on a diet restricted to low - fat, high - fiber foods until any inflammation has gone down.

It's a built - in challenge for those who want it, but for less patient players or newcomers perhaps put off by talk of roguelikes being punishing, the slow - building progression helps level the playing field if needed.

The Diabetes Control and Complications trial has provided conclusive evidence that strict glycemic control in patients with type 1 diabetes can both delay the onset of microvascular complications and slow the rate of progression of already established complications.