They found that a particular variant of the MBP gene was significantly more common in the MS
patients than in the controls.
Not exact matches
Intarcia has completed several late - stage clinical trials
in which it uses the pump to deliver a glucose -
controlling drug continuously for months — an idea, that if successful (and approved by the FDA) could significantly help
patients with type 2 diabetes, fewer
than half of whom maintain the recommended glycemic levels.
Final
patient visits will be followed by completing data entry for the more
than 35,000
patient years of study
in REDUCE - IT, and typical database quality
control measures, known as cleaning.
When labor time came, I was able to make fully informed decisions about my birth and felt like I was the one
in control of my experience, rather
than a
patient whose baby was «being delivered.»
When labor time comes, I want you to feel like you are the one
in control of your experience, rather
than a
patient whose baby is «being delivered.»
A study of mental functioning
in alcoholic
patients found that they performed less well
than a
control group
in choosing the correct punchline for a joke.
In trials involving two groups of diabetic
patients, adults and adolescents, the bionic pancreas provided tighter
control of blood glucose
than standard measures such as insulin pumps and blood - sugar monitors.
Patients newly diagnosed with primary SjS (
in people with no other rheumatic disease) were around 11 times more likely to have had a prior infection with NTM
than a matched group of
controls.
When, for example, subjects were asked 20 times
in succession to estimate the duration for which a square — displayed for exactly one second
in each case — appeared on the screen, the estimates given by
patients with schizophrenia exhibited a much higher level of variability
than those of the
control group.
Immunotherapy with a live bacterium combined with chemotherapy demonstrated more
than 90 % disease
control and 59 % response rate
in patients with malignant pleural mesothelioma (MPM), according to the results of a phase Ib trial presented today at the European Lung Cancer Conference (ELCC) 2016
in Geneva, Switzerland.1
Another problem is that modeling studies, like this one, are inherently less powerful
than other kinds of medical research: randomized clinical trials, the gold standard
in medical research,
in which
patients are randomly assigned different treatments or no treatment; case -
control studies, which compare
patients who have a condition with those who do not; or cohort studies, which determine the risk of contracting a disease by studying a group of people with similar demographics.
Nearly half (48 %) of
patients with severe or difficult - to - treat asthma
in The Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens follow - up study (TENOR II) still had very poorly
controlled (VPC) symptoms after more
than a decade of treatment, according to a new study presented at the ATS 2016 International Conference.
An outpatient with well -
controlled episodic migraine may respond differently
than someone with chronic migraine or a
patient in the emergency room.
Maintaining or achieving blood pressure
control in patients with arthritis and concomitant hypertension (treated or untreated) could avoid more
than 70,000 deaths from stroke and 60,000 deaths from coronary heart disease each year, 2 making it important to investigate the effects of various NSAIDs on blood pressure.
Researchers at the Chemical Abuse Centers
in Boardman, Ohio, found that combining magnesium oxide with the drug verapamil helped
control manic symptoms
in patients better
than a drug - placebo combination.
«The significant improvement
in overall survival with pembrolizumab was remarkable given that more
than 40 % of
patients crossed over from the
control arm to pembrolizumab after progression of the disease,» said Reck.
Still other technologies use brain implants similar to those
in the new study, but to
control robotic arms, external skeletons, or computer cursors, rather
than the
patient's own muscles.
High - intensity exercise can help stable heart transplant
patients reach higher levels of exercise capacity, and gain better
control of their blood pressure
than moderate intensity exercise, investigators report
in a new study published
in the American Journal of Transplantation.
Studying these mechanisms provided the researchers with «a source of variation that we think is effectively random,» says Doyle, adding that it represents «hopefully a better apples - to - apples comparison» of
patients than prior studies that did not try to
control for differences
in which kinds of
patients visit which hospitals.
More
than 500,000
patients every year develop an SSI, according to the Centers for Disease
Control and Prevention (CDC).1 Orthopedic procedures have a low SSI rate, ranging from 0.7 to 2.1 infections for every 100 cases.2 Nevertheless, orthopedic surgery
patients with SSIs have a two times higher rate of rehospitalization and a 300 percent increase
in treatment costs.3
In the study, MBSR participants reported significantly greater improvement in the ability to pay attention, and also made fewer mistakes on difficult cognitive tasks than those in the control group, which received patient education materials and supportive counselin
In the study, MBSR participants reported significantly greater improvement
in the ability to pay attention, and also made fewer mistakes on difficult cognitive tasks than those in the control group, which received patient education materials and supportive counselin
in the ability to pay attention, and also made fewer mistakes on difficult cognitive tasks
than those
in the control group, which received patient education materials and supportive counselin
in the
control group, which received
patient education materials and supportive counseling.
On the second day,
patients in the methadone group required less
than 1 mg of hydromorphone, compared to 3 mg
in the
control group.
On the third day,
patients in the methadone group didn't require hydromorphone, compared to less
than 1 mg
in the
control group.
«
In our large population - based study of more
than 6,000 adults with CAP and almost 30,000 matched
controls, we found that CAP
patients have high rates of long - term morbidity and mortality compared to those who have never had CAP, irrespective of their age.»
A study
in Japan found that
patients who listened to nature sounds during surgery emerged from general anesthesia more smoothly
than a
control group who heard the procedure; the latter experienced significantly higher heart rate and blood pressure while returning to consciousness.
«When studying magnetic resonance images of the brains of
patients suffering from CRPS, we noticed that the choroid plexus was nearly one - fifth larger
in patients than in healthy
control subjects,» says Postdoctoral Researcher Guangyu Zhou from Aalto University Department of Neuroscience and Biomedical Engineering (NBE), who analysed the images.
After a year, significantly fewer myelin - treated
patients had major attacks of multiple sclerosis (6 out of 15)
than in the
control group (l2 out of 15).
In a randomized
controlled clinical trial, scientists from Joslin Diabetes Center and Brigham and Women's Hospital found that
patients treated with a form of bariatric surgery known as Roux - en - Y gastric bypass did significantly better, after three years,
than patients provided with an intensive diabetes and weight management program.
The results showed that a significantly lower proportion of different bacteria are found
in the gut
in patients with heart failure
than in healthy
controls.
Most of these men, who all had terminal prostate cancer with limited treatment options, had disease
control lasting much longer
than expected
in this group of
patients.
Another fact revealed by the study supporting food supremacy was that
in all three groups,
patients and
control, food information was processed better
than «non — food.»
Favourable outcomes, ranging from moderate disability to good recovery, occurred
in only a quarter of the
patients in the hypothermia group compared with more
than a third of
patients in the
control group.
But it did not appear
in any of the more
than 300
controls from France and Italy or
in 52 Italian
patients with sporadic Parkinson's disease.
More
than half of the ESC / E (Z) genes were over-expressed
in PMDD
patients» cells, compared to cells from
controls.
The study, published
in the September issue of Infection
Control and Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America, demonstrates that the risk of CLABSI with PICCs is based more on
patient factors, rather
than the device.
The disease
control rate (defined as partial response or stable disease for more
than 12 weeks) for all
patients was 32 percent (6 of the 19
patients) and 50 percent (three of six
patients)
in patients who received one prior line of chemotherapy.
The analysis revealed that while performing working memory tasks, the young
patients with concussion had initial activation that was greater
than normal, known as hyperactivation, compared to young
controls in the right precuneus and right inferior parietal gyrus of the brain, whereas the older
patients had hypoactivation (less
than normal) compared to older
controls in the right precuneus and right inferior frontal gyrus.
Shannon entropy analysis of FA histograms performed better
than mean FA as a diagnostic test to differentiate between concussion
patients and
controls and also performed better
in determining which concussion
patients developed post-traumatic migraines.
It is not clear how comparable these
controls were
in their disease stage with the treated
patients, so it's hard to be sure that the treated
patients did better
than they would have otherwise.
Other studies have shown that asthma
patients experience more constricted airways
than healthy
control subjects
in response to emotional stimuli.
MRI scans of the
patients» brains showed that those
in the tDCS group had more activity
in the relevant brain areas for motor skills
than those
in the
control group.
Patients who received automated telephone calls inviting them to get their blood pressure checked at a walk - in clinic were more likely to have controlled hypertension than patients who did not receive calls, according to a Kaiser Permanente study published today in the Journal of Clinical Hyper
Patients who received automated telephone calls inviting them to get their blood pressure checked at a walk -
in clinic were more likely to have
controlled hypertension
than patients who did not receive calls, according to a Kaiser Permanente study published today in the Journal of Clinical Hyper
patients who did not receive calls, according to a Kaiser Permanente study published today
in the Journal of Clinical Hypertension.
Moreover,
in another Japanese
patient, they identified a homozygous frameshift (p.L206fs), absent
in more
than 2,500 chromosomes from ethnically matched
controls,
in the ciliary gene NEK2, encoding a serine / threonine - protein kinase.
At study entry, serum transthyretin levels were modestly lower
in patients with transthyretin amyloidosis
than in healthy volunteers, a finding that was consistent with reports showing lower transthyretin levels
in patients with transthyretin amyloidosis
than in either asymptomatic disease carriers or healthy
controls.36
Influenza remains a major health problem
in the United States, resulting each year
in an estimated 36,000 deaths and 200,000 hospitalizations.4 Those who have been shown to be at high risk for the complications of influenza infection are children 6 to 23 months of age; healthy persons 65 years of age or older; adults and children with chronic diseases, including asthma, heart and lung disease, and diabetes; residents of nursing homes and other long - term care facilities; and pregnant women.4 It is for this reason that the Centers for Disease
Control and Prevention (CDC) has recommended that these groups, together with health care workers and others with direct
patient - care responsibilities, should be given priority for influenza vaccination this season
in the face of the current shortage.1 Other high - priority groups include children and teenagers 6 months to 18 years of age whose underlying medical condition requires the daily use of aspirin and household members and out - of - home caregivers of infants less
than 6 months old.1 Hence,
in the case of vaccine shortages resulting either from the unanticipated loss of expected supplies or from the emergence of greater -
than - expected global influenza activity — such as pandemic influenza, which would prompt a greater demand for vaccination5 — the capability of extending existing vaccine supplies by using alternative routes of vaccination that would require smaller doses could have important public health implications.
Patients with HbA1C in the prediabetes range, 5.7 - 6.4 percent, were considered to be intensively treated if using two or more medications at the time of the test, or if started on additional medications after the test, because current guidelines consider patients with HbA1C less than 6.5 percent to be optimally controlled
Patients with HbA1C
in the prediabetes range, 5.7 - 6.4 percent, were considered to be intensively treated if using two or more medications at the time of the test, or if started on additional medications after the test, because current guidelines consider
patients with HbA1C less than 6.5 percent to be optimally controlled
patients with HbA1C less
than 6.5 percent to be optimally
controlled already.
U.S.
patients were more likely to have adequate
control; 63 percent met the recommended pressure of less
than 140/90, compared to only 31 percent
in Italy, 36 percent
in the United Kingdom, 40 percent
in Spain and Germany, and 46 percent
in France.
No reports have examined the degree of heteroplasmy (presence of more
than one type of mitochondrial genome)
in ME / CFS
patients vs.
controls.
Patients in the MSC group showed significantly higher B - cell levels
than the
control group at 3 month post-transplant.
Using GCTA, the researchers analyzed the same genetic datasets screened
in the Molecular Psychiatry reports — almost 1,500 individuals affected with OCD compared with more
than 5,500
controls, and nearly TS 1,500
patients compared with more
than 5,200
controls.