His group gives particular thought to ways in which scientists document and describe the nonrandom
pattern of human genetic variation and its link to disease risks in different populations.
Many other geographic, climatic, and historical factors have contributed to
the patterns of human genetic variation seen in the world today.
The patterns of human genetic variation, however, correspond poorly with visible morphological differences.
Not exact matches
The research in his laboratory involves the study
of the nature and extent
of human immunodeficiency virus (HIV)
genetic variation, the biological and evolutionary processes that have produced the observed
patterns, and the
human genes and their relevant
genetic variants that influence susceptibility or resistance to HIV infection.
By analyzing these two exomes together with the genome sequence
of a Neandertal from Siberia we show that the
genetic diversity
of Neandertals was lower than that
of present - day
humans and that the
pattern of coding
variation suggests that Neandertal populations were small and isolated from one another.
«This is a dramatic example
of how recent
human history has profoundly shaped
patterns of genetic variation,» said Joshua Akey,...