Sentences with phrase «patterns of gene»

However, inferring dispersal capability from life history characteristics should be undertaken with caution, given that life history only partially explains the observed patterns of gene flow for other marine species [60], [61].

The muscles of the mice receiving both the drug and the training also showed evidence of new patterns of gene activity not seen in mice taking the drug alone or exercise training alone.

CT values for cyclophilin were somewhat more variable in cells isolated by flow cytometry and frozen prior to analysis, compared to freshly isolated and unmanipulated cells, but the gradients in patterns of gene expression were similar for cells isolated by the two techniques (Figure 3a — d).

Global analysis of patterns of gene expression during Drosophila embryogenesis.

What's more, the epigenome helps ensure that patterns of gene expression are preserved when cells divide.

Systematic determination of patterns of gene expression during Drosophila embryogenesis P. Tomancak, A. Beaton, R. Weiszmann, E. Kwan, S. Shu, S.E. Lewis, S. Richards, M. Ashburner, V. Hartenstein, S.E. Celniker and G.M. Rubin Genome Biology (2002) 3 (12): research0088.1 - 0088.14 Download entire paper in pdf format

«It's been a puzzle that lots of leukemias exhibit mixed lineage patterns of gene expression - for example of both macrophage and lymphocyte genes,» he said.

Adipose tissues from various anatomical sites are characterized by different patterns of gene expression and regulation

Analyzing patterns of gene expression in individual human immune system cells, the researchers refined the definitions of the types known as dendritic cells and monocytes and identified a novel type that had been overlooked.

Confirming this prediction for several dozen HARs, our next goal was to see whether any of these HARs enhanced patterns of gene activation that were uniquely human.»

The finding is a landmark in the new field of evolutionary developmental biology, or «evo - devo,» as its proponents call it, in which scientists study the patterns of gene expression in embryos to peer backward in time.

«The cells that fuel the development of tumors in the adult are unlikely to «invent» entirely new patterns of gene expression,» says Benjamin Spike.

-LSB-...] Back in December, I wrote about two studies that compared global patterns of gene expression between germ cells and somatic cells in Volvox carteri, one by Benjamin Klein, Daniel Wibberg and Armin Hallmann from the University of Bielefeld in Germany and one by Gavriel Matt and Jim Umen from Washington University in St. Louis and the Donald Danforth Plant Science Center, respectively.

A dizzying number of genetic transcripts, proteins and other molecular players alternatively glom together or fall apart, turning on or tuning down countless patterns of gene expression that keep our cells, organs and bodies humming along with the Earth's daily rotations.

The same can be said for patterns of gene expression changes in the same brain region for different age frames.

They show patterns of gene mutation and gene repair, as well as patterns of natural selection.

Characterization of patterns of gene expression across tissues, individuals and species (Guigo, Estivill and Notredame's groups, Genome Research 2012, Genome Research 2014, Nature 2014, Nature 2014, Nature Communications 2015, Science 2015, PNAS 2015, Genome Biology 2016).

Many leukemias exhibit mixed - lineage patterns of gene expression, for example of both macrophage and lymphocyte genes.

Retinas recovering from hypoxia also showed distinct patterns of gene expression that were different from both normoxic control retinas and hypoxic retinas, indicating that hypoxia initiates a complex pattern of gene expression.

And next - generation sequencing, in particular, RNA sequencing, allows researchers to delineate changing patterns of gene expression as new cell types form.

The CRG team has been working for a long time to achieve detailed quantitative analyses of Mycoplasma pneumoniae at every level: from genetics to metabolism, including patterns of gene activity and protein composition, and more.

The team has created a publicly accessible database for researchers of all the patterns of gene activation that differ between male and female pigeons.

Because genes on the Y chromosome often vary slightly in sequence — and even function — from the corresponding genes on the X, males could have slightly different patterns of gene expression throughout the body compared with females, due to not only their hormone levels, but also their entire Y chromosome.

The researchers also compared patterns of gene activation in organoid cells to a database of human brain genetic information.

Patterns of gene expression in the two kinds of plants confirm the similarity, Hedrich says.

Much of the previous research on epigenetics has focused on the fact that everyday experiences alter patterns of gene activity in DNA during life through a chemical process of gene tagging called methylation, which usually silences genes.

Hochedlinger and his colleagues note that several factors could explain why iPS cells and ES cells show different patterns of gene activity.

By revealing patterns of gene activity, the mouse atlas has allowed neuroscientists to identify functionally important regions that were invisible simply by looking at the brain's anatomy.

Bhaduri then used statistical algorithms to cluster different cells based on their patterns of gene expression.

Other researchers used new techniques «to compare patterns of gene expression, to determine what was stressing the bees,» said Berenbaum.

But brain cells that had been created using the direct conversion technique had different patterns of gene expression depending on whether they were created from young donors or older adults.

Surprisingly, they found that although the patterns of gene expression — as shown by the RNA sequencing — differed between the hepatocellular carcinomas and the liver cancers with biliary phenotype and depended on the histological type, the overall pattern of mutations in the cells was actually similar between the tumors — of either type — that had emerged in patients who had had infections with either hepatitis C or B, and were different in patients without such infections.

Then, they compared the patterns of gene expression in the resulting neurons with cells taken from autopsied brains.

In a 2015 study of 46 people, Bearden found that people with 22q11.2 deletion syndrome who have autism show different patterns of gene expression than do those with the syndrome who have schizophrenia3.

However, all regions of the human brain have molecular signatures very similar to those of our primate relatives, yet some regions contain distinctly human patterns of gene activity that mark the brain's evolution and may contribute to our cognitive abilities, a new Yale - led study has found.

Yamanaka's group and two others followed up earlier this year with firmer evidence that these induced pluripotent stem (iPS) cells faithfully mimicked the patterns of gene activity and cellular differentiation observed in embryonic stem cells.

Our work shows an exciting new way that eRNAs produce these different patterns of gene expression.

Prof Tony Green, an author from the Wellcome Trust - MRC Stem Cell Institute and Cambridge University, said: «The SC3 tool was able to use patterns of gene expression to distinguish, within an individual cancer, subclones that carried different mutations.

Another analysis focused on the patterns of gene activation during diapause, which the embryos of N. furzeri may undergo during the dry seasons.

When these mice develop, their internal organs and patterns of gene expression fall randomly into left - or right - oriented layouts.

Several years ago, NCI scientists identified the two primary subtypes of DLBCL based on characteristic patterns of gene activity within the lymphoma cells.

Using breast cancer patient data taken from The Cancer Genome Atlas, molecular biologists Curt M. Horvath and Robert W. Tell used powerful computational and bioinformatics techniques to detect patterns of gene expression in two cancer subtypes.

The scientists then studied the patterns of gene expression in these mice.

Typically, cells of the same type have matching patterns of gene activity — many of the same genes are turned off or on in all cells.

Researchers have videotaped cultures in which embryos develop but found no visual pattern that hints at which cells are about to sprout, and staining for certain patterns of gene expression has been inconclusive.

When the scientists compared the workers that started reproducing with those that didn't, they found that the two groups had different patterns of gene methylation.

Most research on epigenetics has focused on the way everyday experiences alter patterns of gene activity in DNA during life through a chemical process of gene tagging called methylation, which usually silences genes.

His team is now looking at patterns of gene activity in the four brains to work out whether it is possible to detect early signs associated with conditions like autism.

These areas in parrots also show some special patterns of gene expression, which the scientists speculate might explain why some parrots are also able to learn to dance to music.

Despite the anatomical complexity of the brain and the complexity of the human genome, most of the patterns of gene usage across all 20,000 genes could be characterized by just 32 expression patterns.