Sentences with phrase «patterns of gene activity»

The muscles of the mice receiving both the drug and the training also showed evidence of new patterns of gene activity not seen in mice taking the drug alone or exercise training alone.

The CRG team has been working for a long time to achieve detailed quantitative analyses of Mycoplasma pneumoniae at every level: from genetics to metabolism, including patterns of gene activity and protein composition, and more.

Much of the previous research on epigenetics has focused on the fact that everyday experiences alter patterns of gene activity in DNA during life through a chemical process of gene tagging called methylation, which usually silences genes.

Hochedlinger and his colleagues note that several factors could explain why iPS cells and ES cells show different patterns of gene activity.

By revealing patterns of gene activity, the mouse atlas has allowed neuroscientists to identify functionally important regions that were invisible simply by looking at the brain's anatomy.

However, all regions of the human brain have molecular signatures very similar to those of our primate relatives, yet some regions contain distinctly human patterns of gene activity that mark the brain's evolution and may contribute to our cognitive abilities, a new Yale - led study has found.

Yamanaka's group and two others followed up earlier this year with firmer evidence that these induced pluripotent stem (iPS) cells faithfully mimicked the patterns of gene activity and cellular differentiation observed in embryonic stem cells.

Several years ago, NCI scientists identified the two primary subtypes of DLBCL based on characteristic patterns of gene activity within the lymphoma cells.

Typically, cells of the same type have matching patterns of gene activity — many of the same genes are turned off or on in all cells.

Most research on epigenetics has focused on the way everyday experiences alter patterns of gene activity in DNA during life through a chemical process of gene tagging called methylation, which usually silences genes.

His team is now looking at patterns of gene activity in the four brains to work out whether it is possible to detect early signs associated with conditions like autism.

Two of the mouse's genes had been altered so that the egg had a pattern of gene activity similar to that of a sperm.

The findings may even have implications for studying glioblastoma, a common brain cancer whose ability to grow, migrate and hack into the brain's blood supply appears to rely on a pattern of gene activity similar to that now identified in these neural stem cells.

The studies demonstrate that the daily pattern of gene activity is not lost with age but is rather reprogrammed for new functions and that a low calorie diet delays alterations in the rhythm of stem cells.

Not exact matches

PER and TIM block the ability of CLOCK to turn on these genes at the same time as they are producing the oscillations of the central feedback loop — setting up extended patterns of cycling gene activity.

«While these findings are specific to HD and PD, these two diseases are sufficiently distinct to suggest that the observed pattern of differential gene activity may likely be observed in other neurodegenerative diseases of the central nervous system, including Alzheimer's disease and Chronic Traumatic Encephalophathy (CTE).»

Compared with living people, Neandertals and ancient Siberians known as Denisovans had slightly different patterns of DNA methylation — a chemical modification of DNA that doesn't change the information in genes but helps control gene activity.

«Gene analysis adds layers to understanding how our livers function: Tracking gene expression patterns for 20,000 gene in 1,500 cells revealed a mosaic of activities.&raGene analysis adds layers to understanding how our livers function: Tracking gene expression patterns for 20,000 gene in 1,500 cells revealed a mosaic of activities.&ragene expression patterns for 20,000 gene in 1,500 cells revealed a mosaic of activities.&ragene in 1,500 cells revealed a mosaic of activities.»

The fact that the researchers made their iPS cells from cells that matured in the lab from ES cells, instead of from the cells of a patient or donor, means that they still might carry traces of the ES cells» gene activity patterns.

Other characteristic patterns of variants included genes involved in immune system activity and the fat content of breast milk.

Whereas liver and blood gene activity patterns showed the expected differences among the three groupswith human transcription looking similar to that of the chimp, and different from that of the more evolutionarily distant macaquegene activity in the brain revealed stark differences between humans and chimps.

At the time, Martin Cohn, an evolutionary developmental biologist at the University of Florida in Gainesville, discovered snake embryos had a different pattern of activity of certain genes than other reptiles and that applying a growth factor could make those embryos start to grow limbs.

The researchers found that gene expression patterns in the hippocampus accurately predicted whether the mice were in a state of high or low locomotor activity.

Knockdown of both dec1 and per2 genes resulted in a noticeably disrupted circadian locomotor activity pattern.

The molecules central to this balancing act, H3K4me3 and H3K27me3, are among the so - called epigenetic modifications that influence the activity patterns of genes in both human embryonic stem (ES) cells and mature human adult cells.

The development of an embryo, for example, looks like a well - programmed process, orchestrated by predictable waves of gene activity to produce a specific pattern of tissues.

The current report, which appears in the May 4, 2012 issue of the journal Cell Stem Cell, shows that these cells can also change their epigenomes, the patterns of DNA modifications that regulate the activity of specific genes — sometimes radically.

Gaining access to the inner workings of a neuron in the living brain offers a wealth of useful information: its patterns of electrical activity, its shape, even a profile of which genes are turned on at a given moment.

The gene variant produced a telltale pattern of activity linked to production of a key brain messenger chemical.

They also support the existence of four related subtypes based on the patterns of DNA methylation — a chemical reaction in which a small molecule called a methyl group is added to DNA, changing the activity of individual genes.

Cell activity patterns of two gene enhancers (red and green cells).

LMU researchers have shown that patterns of activity of certain genes in vertebrate embryos correlate with differences in the length of the neck region.