Provincial governments, strapped for cash and facing ballooning deficits, have been hacking away at the prices
they pay for generic drugs.
Not exact matches
The chairman of Apotex, the largest producer of
generic drugs in Canada, came under fire recently
for helping to organize a $ 500 - per - ticket
pay -
for - access fundraiser
for the party.
After all, patients and doctors who choose Valeant's
drugs when an identical
generic version is available are already volunteering to
pay extra
for the brand name.
Often it turns out that the price increases by Valeant and Turing that have provoked the most criticism have been on
drugs that are off - patent — meaning
generic competitors are free to enter the market, typically bringing the price that most people
pay for the
drugs way down.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues
for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement
for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding
for state AIDS
Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the S
Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of
generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new
drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the S
drug applications
for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all,
for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to
pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
It's the first so - called «
pay for delay» case brought by the commission in which a
drug's original maker agreed not to sell its own «authorized
generic» version until well after a
generic drugmaker began selling its product.
To avoid
paying # 400 a month
for private prescriptions of the brand - name
drug Truvada, growing numbers are buying
generic versions from online pharmacies in India and Swaziland
for # 40 a month, through a UK website called I Want PrEP Now.
Controversial deals that delay
generic versions of
drugs coming onto the market can lead to consumers
paying significantly more
for some treatments, according to new research by an academic from the University of East Anglia.
* Eliminate «
pay -
for - delay» strategies in which a pharmaceutical company with a brand name
drug shares profits on that
drug with a
generic drug manufacturer
for the remainder of a patent period, effectively eliminating a patent challenge and competition.
Novartis unbelievably went as far as
paying specialty pharmacies to recommend Tasigna to Medicare and Medicaid patients who were trying to fill prescriptions
for other
drugs (potentially
generic imatinib) and to downplay the side effects of Tasigna to patients considering switching
drugs.
Pre-65 retirees will not have to
pay for certain specified
generic maintenance
drugs.
Pay -
for - delay («PFD») agreements are agreements that are intended to delay the market entry of
generic manufacturers with
generic drugs in exchange
for payments made by original pharmaceutical producers (i.e., holders of patents
for an original branded
drug).
In a decision released in July, Merck & Co., Inc. v. Apotex Inc., 2013 FC 751, Justice Snider held that Apotex must
pay $ 119 million in damages
for its sale of
generic lovastatin, a cholesterol
drug, which infringed one of Merck's patents.
Tier 1 is
generic drugs, which you
pay the least
for; the tiers get more expensive as you go up the ladder.