In addition, the LEAP study design excluded 9.1 % of the infants who were screened (76 of 834) because large wheals (greater than 4 mm in diameter) developed after the skin - prick test21 that were probably associated with peanut allergy; the safety and effectiveness of
early peanut consumption in that population remain unknown.
Nine participants who were randomly assigned to
peanut consumption subsequently discontinued consumption (Table S10 and the Results section in the Supplementary Appendix).
«This study demonstrated a strong inverse association
between peanut consumption in infancy and the prevalence of PA [Peanut Allergy] in childhood.
«Because peanuts [which do not grow on trees] are much less expensive than tree nuts, as well as more widely available to people of all races and all socioeconomic backgrounds, our study finding suggests that
increasing peanut consumption may provide a potentially cost - efficient approach to improving cardiovascular health,» Shu said.
The U.S. group in the top 20 percent of
peanut consumption ate more than 18 grams a day, or about 0.63 ounces — roughly 2 tablespoons of shelled peanuts, Shu said.
The results of the Immune Tolerance Network's (ITN) «Persistence of Oral Tolerance to Peanut» (LEAP - ON), discussed on March 4, 2016 at the American Academy of Allergy, Asthma & Immunology Annual Meeting and published in the New England Journal of Medicine, demonstrate that peanut allergy prevention achieved from
early peanut consumption in at - risk infants persists after a one - year period of avoiding peanut.
From some research I found, it appears that the advent of the Hib vaccine (Haemophilus influenza type B) in the early 1990's in the USA and in 2001 in Sweden (and various dates in other countries) has created high rates of peanut allergy regardless
of peanut consumption.
This indicates that
peanut consumption may not be possible in some children who meet the LEAP eligibility criteria.
Children in
the peanut consumption arm of the trial ate a peanut - containing snack - food at least three times each week, while children in the peanut avoidance arm did not ingest peanut - containing foods.
«That said, the totality of evidence from nutrition and health research suggests that nut and
peanut consumption can be considered a healthy lifestyle choice,» she said.
«Peanut avoidance was associated with a greater frequency of clinical peanut allergy than was
peanut consumption, which raises questions about the usefulness of deliberate avoidance of peanuts as a strategy to prevent allergy.»