Sentences with phrase «pediatric gliomas»
In a second study, described online Oct. 14 in Modern Pathology, the Johns Hopkins investigators sought a genetic source that could accurately identify subsets of low - grade pediatric gliomas, the most frequent tumors of the central nervous system in children.
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In 2015, her lab published a paper in Cell (DOI: 10.1016 / j.cell.2015.04.012) that found that both adult and pediatric glioma cells grew faster when adjacent to highly active neurons.
Not exact matches
Frustrated with the lack of investment in research and drug development devoted to pediatric brain tumor gliomas, the Kamens decided to take action and launch their foundation.
Researchers from Northwestern Medicine and Ann & Robert H. Lurie Children's Hospital of Chicago have revealed new insight into how the most deadly pediatric brain tumor, diffuse intrinsic pontine glioma (DIPG), may develop.
The tumors studied fell into the broad category of high - grade gliomas: diffuse intrinsic pontine glioma, which strikes school - aged children; pediatric cortical glioblastoma, which affects primarily teens and young adults; anaplastic oligodendroglioma, which affects young adults; and glioblastoma multiforme, which affects older adults.
Researchers investigating pediatric low - grade gliomas (PLGG), the most common type of brain tumor in children, have discovered key biological differences in how mutated genes combine with other genes to drive this childhood cancer.
«This is exciting because it's the first animal model of pediatric high - grade gliomas, or malignant brain tumors,» says Maria Castro, Ph.D., senior author of the paper and a professor in the departments of Neurosurgery and Cell and Developmental Biology at U-M.
Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas.
Also this week, members of the St. Jude Children's Research Hospital — Washington University Pediatric Cancer Genome Project (PCGP) described the whole - genome sequencing pediatric diffuse intrinsic pontine glioma (DIPG), 7 cases with tumor and matched germline DNA.
Screening of several other pediatric brain tumors revealed that the histone H3 mutations seem exclusive to pediatric high - grade gliomas.
Research from the Pediatric Cancer Genome Project has identified new mutations in pediatric brain tumors known as high - grade gliomas, including tumors like diffuse intrinsic pontine glioma pictured in this MRI.
The St. Jude Children's Research Hospital - Washington University Pediatric Cancer Genome Project has identified new mutations in pediatric brain tumors known as high - grade gliomas (HGGs), which most often occur in the youngest patients.
U-M's internationally renowned Translational Neuro - Oncology Laboratory generates novel primary cell cultures from pediatric and adult glioma tissue samples to study mechanisms of glioma growth and targeted treatment response.